METHODS OF DETERMINING THE PRESENCE AND/OR CONCENTRATION OF AN ANALYTE IN A SAMPLE
First Claim
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1. A method comprising:
- providing an analyte;
providing an analyte receptor and an indicator, wherein at least a portion of the analyte receptor and the indicator form a receptor/indicator complex;
contacting the receptor/indicator complex with the analyte; and
allowing the analyte to interact with the receptor/indicator complex so as to generate a detectable signal.
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Abstract
Compositions, methods, and systems for monitoring analyte levels are provided herein. The disclosure provides methods and systems for the real-time monitoring of analytes, such as citrate, calcium, phosphate and magnesium, in a biological fluid in a clinical setting.
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Citations
21 Claims
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1. A method comprising:
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providing an analyte; providing an analyte receptor and an indicator, wherein at least a portion of the analyte receptor and the indicator form a receptor/indicator complex; contacting the receptor/indicator complex with the analyte; and allowing the analyte to interact with the receptor/indicator complex so as to generate a detectable signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A system comprising:
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a receptor/indicator complex comprising an analyte receptor and an indicator; and an analyte, wherein the analyte will displace the indicator in the receptor/indicator complex; and
wherein the displaced indicator will generate a detectable signal. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21)
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Specification