PATHOGEN DETECTION BY SIMULTANEOUS SIZE/FLUORESCENCE MEASUREMENT
First Claim
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1. A method of differentiating biological particles from inert particles in a fluid which comprises simultaneously measuring a particle size and detecting intrinsic fluorescence from that particle.
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Abstract
A method and apparatus for detecting pathogens and particles in a fluid in which particle size and intrinsic fluorescence of a simple particle is determined.
12 Citations
36 Claims
- 1. A method of differentiating biological particles from inert particles in a fluid which comprises simultaneously measuring a particle size and detecting intrinsic fluorescence from that particle.
- 12. A method for detecting and classifying a particle in a liquid or gas comprising illuminating the particle with a UV light source, and simultaneously measuring a size of the particle and any intrinsic fluorescence from the particle.
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26. A particle detector system, comprising:
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a sample cell; a light source on one side of a sample cell for sending a focused beam of light through the sample, whereby portions of the beam of light are scattered at various angles by particles of various sizes present in the sample area, and an unscattered portion of the beam of light remains unscattered; a beam blocking device on an opposite side of the sample cell for blocking at least the portion of the unscattered portion of the beam of light and for limiting a range of particles measured; a first detector positioned in the light path after the beam blocking device for detecting a portion of forward scattered light, and producing an output including information on the size of a single particle in the light path within a predetermined size range; a second detector positioned off axis from the beam of light for detecting intrinsic fluorescence from said same single particle. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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Specification