DAMPING SYSTEMS FOR STABILIZING MEDICATIONS IN DRUG DELIVERY DEVICES
First Claim
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1. A medication infusion pump comprising:
- a housing;
a fluid medication reservoir disposed within the housing and adapted to store a medication to be administered to a user; and
a damping system adapted to inhibit agitation of a medication stored within the fluid medication reservoir, wherein the damping system;
comprises one or more layers of a damping material disposed between the housing and the medication reservoir; and
envelopes the fluid medication reservoir.
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Abstract
The invention relates to systems and methods for stabilizing therapeutic formulations used in medical devices. In particular, the invention relates to systems designed to inhibit the aggregation of therapeutic molecules such as polypeptides stored within a medication delivery device, for example polypeptide aggregation that can result from jostling the medication within a fluid medication reservoir. In embodiments of the invention, a damping system is operably connected to a fluid medication reservoir that is disposed within the housing of a device so as to inhibit the agitation of a fluid medication. Typically the damping system comprises one or more energy absorbing materials.
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Citations
20 Claims
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1. A medication infusion pump comprising:
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a housing; a fluid medication reservoir disposed within the housing and adapted to store a medication to be administered to a user; and a damping system adapted to inhibit agitation of a medication stored within the fluid medication reservoir, wherein the damping system; comprises one or more layers of a damping material disposed between the housing and the medication reservoir; and envelopes the fluid medication reservoir. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A medication infusion system comprising:
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infusion set tubing; a medication infusion pump comprising; a housing; a fluid medication reservoir disposed within the housing and adapted to store a medication to be administered to a patient; a damping system adapted to inhibit agitation of a fluid stored within the fluid medication reservoir wherein the damping system; comprises one or more layers of a damping material disposed between the housing and the medication reservoir; and surrounds the fluid medication reservoir; a program memory; a processor for reading and executing the instructions contained in the program memory; a motor adapted to deliver a fluid medication to a user; and an interface that facilitates attachment of the pump to the user; and
/ora reservoir connector that facilitates fluid medication reservoir insertion into and removal from the housing of the medication infusion pump. - View Dependent Claims (12, 13, 14, 15)
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16. A method of inhibiting aggregation of a polypeptide contained in a fluid medication reservoir within a medication infusion pump, wherein the pump is used to deliver a fluid medication to a user, the method comprising using a medication infusion pump comprising:
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a housing; a fluid medication reservoir disposed within the housing and adapted to store a medication to be administered to a patient; and a damping system adapted to inhibit agitation of a fluid stored within the fluid medication reservoir, wherein the damping system; comprises one or more layers of a damping material disposed between the housing and the medication reservoir; and envelopes the fluid medication reservoir; and wherein the inhibition of agitation inhibits the aggregation of a polypeptide contained in the fluid medication reservoir. - View Dependent Claims (17, 18, 19, 20)
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Specification