NON-INVASIVE MONITORING OF BLOOD METABOLITE LEVELS
First Claim
1. A method comprising:
- repeatedly measuring a plurality of electromagnetic impedance readings with a sensor array from;
an epidermis layer of a patient and one of a dermis layer or a subcutaneous layer of the patient, until a difference between the readings exceeds a threshold;
calculating an impedance value representing the difference using an equivalent circuit model and individual adjustment factor data representative of a physiological characteristic of the patient; and
determining a blood metabolite level of the patient from the impedance value and a blood metabolite level algorithm, the blood metabolite level algorithm including blood metabolite level data versus electromagnetic impedance data value correspondence of the patient.
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Accused Products
Abstract
Solutions for non-invasively monitoring blood metabolite levels of a patient are disclosed. In one embodiment, the method includes: repeatedly measuring a plurality of electromagnetic impedance readings with a sensor array from: an epidermis layer of a patient and one of a dermis layer or a subcutaneous layer of the patient, until a difference between the readings exceeds a threshold; calculating an impedance value representing the difference using an equivalent circuit model and individual adjustment factor data representative of a physiological characteristic of the patient; and determining a blood metabolite level of the patient from the impedance value and a blood metabolite level algorithm, the blood metabolite level algorithm including blood metabolite level data versus electromagnetic impedance data value correspondence of the patient.
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Citations
82 Claims
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1. A method comprising:
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repeatedly measuring a plurality of electromagnetic impedance readings with a sensor array from;
an epidermis layer of a patient and one of a dermis layer or a subcutaneous layer of the patient, until a difference between the readings exceeds a threshold;calculating an impedance value representing the difference using an equivalent circuit model and individual adjustment factor data representative of a physiological characteristic of the patient; and determining a blood metabolite level of the patient from the impedance value and a blood metabolite level algorithm, the blood metabolite level algorithm including blood metabolite level data versus electromagnetic impedance data value correspondence of the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 10)
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9. (canceled)
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11. A monitoring system for at least one of a glucose level, an electrolyte level or an analyte level, the monitoring system comprising:
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a sensor array for repeatedly measuring a plurality of electromagnetic impedance readings from;
an epidermis layer of a patient and one of a dermis layer or a subcutaneous layer of the patient, until a difference between the readings exceeds a threshold;a calculator for calculating an impedance value representing the difference, the calculating including using an equivalent circuit model and individual adjustment factor data representative of a physiological characteristic of the patient; and a determinator for determining the at least one of the glucose level, the electrolyte level or the analyte level of the patient from the impedance value and at least one of a glucose algorithm, an electrolyte algorithm or an analyte algorithm. - View Dependent Claims (12, 13, 18, 22, 23, 27, 82)
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14-17. -17. (canceled)
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19-21. -21. (canceled)
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24-26. -26. (canceled)
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28-55. -55. (canceled)
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56. A program product stored on a computer readable medium, which when executed, performs the following:
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determines a blood metabolite level of a patient based on a plurality of electromagnetic impedance readings collected from the patient within a single blood metabolite cycle of the patient, wherein the plurality of electromagnetic impedance readings are non-invasively collected from the patient using a sensor array; and provides instructions for calibrating the sensor array based on the blood metabolite level of the patient and a known blood metabolite level of the patient. - View Dependent Claims (59, 60, 61, 62, 65)
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57-58. -58. (canceled)
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63-64. -64. (canceled)
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66-81. -81. (canceled)
Specification