ELECTRODE STRUCTURES AND METHODS FOR THEIR USE IN CARDIOVASCULAR REFLEX CONTROL
First Claim
1. A method, comprising:
- implanting a baroreceptor activation device within a patient, the baroreceptor activation device including an electrode, wherein the baroreceptor activation device is implanted such that the electrode is on a blood vessel and proximate a baroreceptor in a wall of the blood vessel; and
activating, deactivating, or otherwise modulating the baroreceptor activation device as part of a baroreflex therapy.
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Accused Products
Abstract
Devices, systems and methods are described by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably a baroreceptor located in the carotid sinus. A control system may be used to modulate the baroreceptor activation device. The control system may utilize an algorithm defining a stimulus regimen which promotes long term efficacy and reduces power requirements/consumption. The baroreceptor activation device may utilize electrodes to activate the baroreceptors. The electrodes may be adapted for connection to the carotid arteries at or near the carotid sinus, and may be designed to minimize extraneous tissue stimulation.
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Citations
28 Claims
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1. A method, comprising:
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implanting a baroreceptor activation device within a patient, the baroreceptor activation device including an electrode, wherein the baroreceptor activation device is implanted such that the electrode is on a blood vessel and proximate a baroreceptor in a wall of the blood vessel; and activating, deactivating, or otherwise modulating the baroreceptor activation device as part of a baroreflex therapy. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A system, comprising:
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an extravascular electrode configured for chronic implantation on a blood vessel proximate a baroreceptor within a vascular wall; a controller coupled to the electrode, the controller programmed to deliver a baroreflex therapy to the baroreceptor via the extravascular patch electrode; and an electrical lead coupled between the electrode and the controller. - View Dependent Claims (11, 12, 13, 14, 15)
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16. A method, comprising:
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providing a baroreceptor activation device having an electrode; causing the baroreceptor activation device to be implanted such that the electrode is in contact with an outer surface of a blood vessel so as to be proximate a baroreceptor in a wall of the blood vessel; causing the baroreceptor activation device to be activated, deactivated, or otherwise modulated as part of a chronic baroreflex therapy. - View Dependent Claims (17)
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18. A baroreceptor activation system, comprising:
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a sensor for generating a signal indicative of a need for baroreflex therapy; an electrode configured to be implanted on a blood vessel and proximate a baroreceptor in a wall of the blood vessel; and a signal generator coupled to the sensor and the electrode, the signal generator configured to generate a therapy signal as a function of the sensor signal and deliver the therapy signal through the electrode to the baroreceptor. - View Dependent Claims (19, 20, 21, 22, 23)
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24. A method, comprising:
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providing a baroreceptor activation device having an electrode; and providing instructions, comprising; implanting the baroreceptor activation device within a patient such that the electrode is implanted on a blood vessel so as to be proximate a baroreceptor in a wall of the blood vessel; and activating, deactivating, or otherwise modulating the baroreceptor activation device as part of a chronic baroreflex therapy. - View Dependent Claims (25, 26, 27, 28)
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Specification