SYSTEMS AND METHODS FOR MAGNETIC SEPARATION OF BIOLOGICAL MATERIALS
First Claim
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1. A magnetic separator, comprising:
- a separation chamber having an inlet and at least one outlet opposite the inlet in a downstream direction; and
a magnetic source operatively coupled to the separation chamber and comprising a plurality of magnets that can be selectively turned off and on to create a dynamic magnetic field in the separation chamber.
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Abstract
A magnetic separator comprising a separation chamber is provided. The separation chamber comprises a having an inlet and at least one outlet opposite the inlet in a downstream direction, and a magnetic source operatively coupled to the separation chamber. The magnetic source comprises a plurality of magnets that can be selectively turned off and on to create a dynamic magnetic field in the separation chamber.
18 Citations
27 Claims
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1. A magnetic separator, comprising:
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a separation chamber having an inlet and at least one outlet opposite the inlet in a downstream direction; and a magnetic source operatively coupled to the separation chamber and comprising a plurality of magnets that can be selectively turned off and on to create a dynamic magnetic field in the separation chamber. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A magnetic separation system, comprising:
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one or more magnetic separators, comprising; a separation chamber having an inlet and at least one outlet opposite the inlet in a downstream direction; a magnetic source operatively coupled to the separation chamber and comprising a plurality of magnets configured to be selectively turned on and off to provide a dynamic magnetic field in the separation chamber; a carrier fluid source operatively coupled to the magnetic separator, and configured to provide a continuous laminar flow of a carrier fluid in the magnetic separator; a tagged biological material source operatively coupled to the magnetic separator for introducing two or more tagged biological materials in the magnetic separator, wherein the tagged biological materials comprise two or more biological materials tagged to corresponding one or more magnetically responsive particles. - View Dependent Claims (15, 16, 17, 18, 19)
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20. A method for magnetic separation of a biological material, comprising:
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providing a sample stream having one or more biological materials, wherein the biological materials are associated with one or more magnetically responsive particles; providing a dynamic magnetic field; and exposing the sample stream to the dynamic magnetic field to separate the one or more biological materials from the sample stream. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27)
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Specification