Implantable Medical Device for Treating Neurological Conditions Including ECG Sensing

• US 20120150251A1
• Filed: 06/10/2011
• Published: 06/14/2012
• Est. Priority Date: 04/27/2007
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Giftakis, Jonathon E., Graves, Nina M., Werder, Jonathan C., Panken, Eric J.
• Granted Patent: US 9,014,804 B2
• Time in Patent Office: Days
• US Class Current: 607/17
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
• CPC Class Codes: A61N 1/36114 Cardiac control, e.g. by vagal stimulation stimulating the heart A61N1/362
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters
• CPC Class Codes: A61N 1/37 Monitoring; Protecting
• CPC Class Codes: A61N 1/37512 Pacemakers
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators

Abstract

An implantable medical device such as an implantable pulse generator that includes EEG sensing for monitoring and treating neurological conditions, and leadless ECG sensing for monitoring cardiac signals. The device includes a connector block with provisions for cardiac leads which may be used/enabled when needed. If significant co-morbid cardiac events are observed in patients via the leadless ECG monitoring, then cardiac leads may be subsequently connected for therapeutic use.

Claims

1. An apparatus comprising:

a hermetically sealed implantable device including at least three leadless electrodes located on a housing of the medical device and a brain port;

a lead having a proximal end configured to connect with the brain port, the lead having a distal end with an electrode configured to deliver stimulation to a patient'"'"'s brain;

a processor; and

a computer readable medium in communication with the processor, the computer readable medium comprising executable instructions for causing the processor to perform the following;

enable two of the at least three leadless electrodes for cardiac monitoring based on a post-implantation determination indicating which of the at least three leadless electrodes will be used for cardiac monitoring;

enable one of the at least three leadless electrodes not enabled for cardiac monitoring for acting as an indifferent electrode in monopolar stimulation;

deliver neurostimulation to the patient to treat a neurological condition through the electrode on the distal end of the lead while the one of the at least three leadless electrodes not enabled for cardiac monitoring acts as the indifferent electrode for the neurostimulation; and

monitor for the presence of cardiac events using the two of the at least three leadless electrodes enabled for cardiac monitoring.

2. The apparatus of claim 1 further comprising a cardiac therapy port and a cardiac lead configured to connect with the cardiac therapy port.

3. The apparatus of claim 2 wherein the computer readable medium further comprises executable instructions for causing the processor to select either the cardiac port or the two enabled leadless electrodes for cardiac monitoring.

4. The apparatus of claim 3 wherein the computer readable medium further comprises executable instructions for causing the processor to perform direct cardiac monitoring with the cardiac lead if the cardiac port is selected and, if required, deliver cardiac therapy with the cardiac lead.

5. The apparatus of claim 3 wherein the computer readable medium further comprises executable instructions for causing the processor to perform indirect cardiac monitoring with the two leadless electrodes if the two leadless electrodes are selected, and, if required, deliver cardiac therapy with the cardiac lead.

6. The apparatus of claim 1 wherein the computer readable medium further comprises executable instructions for causing the processor to enable one of the at least three leadless electrodes not enabled for cardiac monitoring for monitoring a brain signal.

7. The apparatus of claim 1 further comprising a second electrode located at the distal end of the lead wherein the electrode and the second electrode are configured to deliver bipolar stimulation.

8. The apparatus of claim 1, wherein the computer readable medium further comprises executable instructions for causing the processor to receive a command indicating which of the at least three leadless electrodes will be used for cardiac monitoring and to enable the two of the at least three leadless electrodes based on the command.

9. The apparatus of claim 1, wherein the neurological condition comprises a seizure disorder.

10. The apparatus of claim 1, wherein the apparatus is configured to deliver the neurostimulation to the patient'"'"'s brain.

11. A method comprising:

dividing a plurality of electrodes on the exterior of an implantable housing for use between cardiac monitoring and brain stimulation;

enabling cardiac monitoring from two of the plurality of electrodes based on the division of the plurality of electrodes;

enabling brain stimulation from one of the plurality of electrodes not enabled for cardiac monitoring based on the division of the plurality of electrodes;

monitoring for cardiac events using the two of the plurality of electrodes enabled for cardiac sensing; and

delivering monopolar stimulation to a patient'"'"'s brain through an electrode on the distal end of a lead, the lead connected to a brain port of the implantable housing, the one of the plurality of electrodes enabled for brain stimulation acting as an indifferent electrode for the neurostimulation, wherein enabling cardiac monitoring, enabling brain stimulation, monitoring, and delivering are each performed at least in part by a processor.

12. The method of claim 11, wherein the implantable housing further comprises a cardiac therapy port.

13. The method of claim 12, further comprising delivering a cardiac stimulation therapy using an electrode on the distal end of a cardiac lead connected to the cardiac port.

14. The method of claim 12, further comprising:

disabling the cardiac therapy port either before or after implantation of the device;

if no cardiac events that may require therapy are identified, maintaining cardiac monitoring using the cardiac sensing port; and

if a cardiac event that may require cardiac therapy is identified, enabling the cardiac therapy port.

15. The method of claim 11, wherein:

dividing the plurality of electrodes further comprises dividing the electrodes for use between cardiac monitoring and brain monitoring; and

the method further comprises enabling brain monitoring from one of the plurality of electrodes not enabled for cardiac monitoring based on the division of the plurality of electrodes.

16. The method of claim 11 wherein the method further comprises delivering bipolar stimulation between the electrode on the distal end of the lead and a second electrode on the distal end of the lead.

17. A system comprising:

means for dividing a plurality of electrodes on the exterior of an implantable housing for use between cardiac monitoring and brain stimulation;

means for enabling cardiac monitoring from two of the plurality of electrodes based on the division of the plurality of electrodes;

means for enabling brain stimulation from one of the plurality of electrodes not enabled for cardiac monitoring based on the division of the plurality of electrodes;

means for monitoring for cardiac events using the two of the plurality of electrodes enabled for cardiac sensing; and

means for delivering monopolar stimulation to a patient'"'"'s brain through an electrode on the distal end of a lead, the lead connected to a brain port of the implantable housing, the one of the plurality of electrodes enabled for brain stimulation acting as an indifferent electrode for the monopolar stimulation.