CONTINUOUS BLOOD GLUCOSE MONITOR

• US 20120165641A1
• Filed: 11/29/2011
• Published: 06/28/2012
• Est. Priority Date: 06/01/2009
• Status: Active Grant

• Current Assignee: Theranova, Llc
• Original Assignee: Theranova, Llc
• Inventors: BURNETT, Daniel Rogers, COVALIN, Alejandro
• Granted Patent: US 9,204,828 B2
• Time in Patent Office: Days
• US Class Current: 600/365
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/4839 combined with drug delivery

Abstract

A device may be implanted subcutaneously with an attached catheter inserted within, e.g., the peritoneal cavity of a subject. The catheter and/or device may also be inserted into another space, e.g., subcutaneous, vascular, peritoneal, cerebrospinal, pleural spaces, etc. The peritoneal fluid which normally collects and/or flows through the peritoneal cavity may be detected by the catheter and analyzed via the device to detect the concentration of glucose within the fluid.

Claims

1. A method of determining a physiologic parameter within a body cavity, comprising:

implanting a sensor in proximity to a peritoneal cavity of a subject;

sensing peritoneal fluid within the cavity via the sensor; and

,

determining a concentration of an analyte from the peritoneal fluid.

2. The method of claim 1 wherein implanting comprises placing a sensing assembly subcutaneously within the subject and a catheter housing the sensor in proximity to the peritoneal cavity.

3. The method of claim 1 wherein determining comprises determining a concentration of glucose from the peritoneal fluid.

4. The method of claim 1 further comprising clearing the sensor in vivo via a valve tip.

5. The method of claim 4 wherein clearing comprises actuating the sensor to move relative to the valve tip thereby clearing the sensor.

6. The method of claim 1 further comprising flushing the sensor with fluid from a fluid reservoir in communication with the sensor.

7. The method of claim 1 further comprising infusing a therapeutic fluid into the subject based upon the concentration of the analyte.

14. The method of claim 1 wherein implanting comprises placing a sensing assembly subcutaneously within the subject and a catheter housing the sensor in proximity to the peritoneal cavity.

8. A method of treating a patient with insulin, comprising:

implanting a sensor in proximity to a peritoneal cavity of a subject;

sensing peritoneal fluid within the cavity via the sensor;

determining a concentration of glucose from the peritoneal fluid; and

,

infusing insulin into the peritoneal cavity based upon the concentration of glucose.

9. The method of claim 8 wherein implanting comprises placing a sensing assembly subcutaneously within the subject and a catheter housing the sensor in proximity to the peritoneal cavity.

10. The method of claim 8 further comprising clearing the sensor in vivo via a valve tip.

11. The method of claim 10 wherein clearing comprises actuating the sensor to move relative to the valve tip thereby clearing the sensor.

12. The method of claim 8 further comprising flushing the sensor with fluid from a fluid reservoir in communication with the sensor.

13. A method of determining a physiologic parameter within a body cavity, comprising:

implanting a sensor in proximity to a peritoneal cavity of a subject;

infusing a peritoneal fluid within the cavity through a semipermeable membrane and into contact with the sensor; and

,

determining a concentration of an analyte from the peritoneal fluid.

15. The method of claim 13 wherein determining comprises determining a concentration of glucose from the peritoneal fluid.

16. The method of claim 13 further comprising clearing the sensor in vivo via a valve tip.

17. The method of claim 16 wherein clearing comprises actuating the sensor to move relative to the valve tip thereby clearing the sensor.

18. The method of claim 13 further comprising flushing the sensor with fluid from a fluid reservoir in communication with the sensor.

19. The method of claim 13 further comprising infusing insulin into the subject based upon the concentration of the analyte.