FABRIC WITH BARBS COATED WITH A WATER-SOLUBLE MATERIAL

• US 20120165937A1
• Filed: 09/06/2010
• Published: 06/28/2012
• Est. Priority Date: 09/04/2009
• Status: Active Grant

• Current Assignee: Sofradim Production
• Original Assignee: Sofradim Production
• Inventors: Montanari, Suzelei, Rey, Pearl
• Granted Patent: US 9,744,019 B2
• Time in Patent Office: Days
• US Class Current: 623/11.11
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61F 2002/30322 differing in surface structures
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2250/0026 differing in surface structures
• CPC Class Codes: A61F 2250/0031 made from both resorbable and non-resorbable prosthetic parts, e.g. adjacent parts
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61L 31/14 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: C08L 71/02 Polyalkylene oxides
• CPC Class Codes: D04B 21/12 characterised by thread material
• CPC Class Codes: D10B 2501/0632 of the touch-and-close type
• CPC Class Codes: D10B 2509/08 Hernia repair mesh

Abstract

The present invention relates to a prosthetic fabric comprising an arrangement of yarns defining at least two faces for said fabric, said fabric comprising, on at least one of its faces, one or more barbs that protrude outwards relative to said face, characterized in that said barbs are covered with a coating made of a water-soluble biocompatible material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.

Claims

1-12. -12. (canceled)

13. Prosthetic fabric comprising an arrangement of yarns defining at least two faces, the fabric comprising on at least one of the faces, one or more barbs that protrude outwards relative to the face, wherein the barbs are covered with a coating made of a water-soluble biocompatible material.

14. The fabric according to claim 13, wherein the water-soluble material is biodegradable.

15. The fabric according to claim 13, wherein the water-soluble material is selected from the group consisting of polyethylene glycols (PEGs), polyvinyl acetates (PVAs), gelatin, polyglucuronic acid, hyaluronic acid, carboxymethyl cellulose, cellulose ethers, chitosans and mixtures thereof.

16. The fabric according to claim 13, wherein the water-soluble material is a polyethylene glycol having a molar mass of less than or equal to 40 000 Da.

17. The fabric according to claim 13, wherein the water-soluble material is a polyethylene glycol having a molar mass of less than or equal to 20 000 Da.

18. The fabric according to claim 16 wherein the molar mass varies from 1000 to 20 000 Da.

19. The fabric according to claim 13, wherein the water-soluble material comprises at least one polyethylene glycol having a molar mass of around 1000 Da.

20. The fabric according to claim 19, wherein the water-soluble material further comprises a polyethylene glycol having a molar mass different from 1000 Da.

25. Prosthesis for the treatment of hernias manufactured from a fabric according to claim 13.

21. Process for covering a prosthetic fabric comprising an arrangement of yarns defining at least two faces, the fabric comprising on at least one of the faces, one or more barbs that protrude outwards relative to the face, comprising the steps of:

preparing a composition including at least one water-soluble biocompatible material in a liquid state; and

applying a layer of the composition to the barbs.

22. The process according to claim 21, wherein the applying step is carried out using a roll.

23. The process according to claim 21, wherein the preparing step includes solubilizing the water-soluble material in water, and optionally heating the composition to the melting point of the water-soluble material.

24. The process according to claim 21, wherein the preparing step includes heating the water-soluble material alone, to a temperature above the melting point of the water-soluble material.

26. Prosthesis for the treatment of hernias manufactured from a fabric obtained by the process according to claim 21.