INHIBITOR OF INFLAMMATORY CONDITIONS
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Abstract
The invention relates to Boswellia frereana and particularly an extract of same for treating a range of inflammatory disorder or conditions selected from the group comprising: articular cartilage degradation or arthritides, osteoarthritis, rheumatoid arthritis, inflammatory bowel disease (IBD), all forms of muscular dystrophy especially Duchenne muscular dystrophy, sepsis, sepsis syndrome, osteoporosis, ischemic injury, graft vs. host disease, reperfusion injury, asthma, diabetes, cancer, myelogenous and other leukemias, psoriasis and cachexia, Alzheimer'"'"'s Disease, demyelinating neurological disorders including multiple sclerosis, Acetylcholinesterase mediated disorders, retinal disorders, neurological, retinal, and muscular disorders.
4 Citations
40 Claims
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1-22. -22. (canceled)
- 23. An extract of Boswellia frereana for use in treating or preventing an inflammatory disease or condition, wherein said extract comprises epi-lupeol or a derivative thereof, other than lupeol, or a salt thereof, and is soluble in organic solution.
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33. A method for obtaining an extract of Boswellia frereana comprising:
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a) obtaining oleo-resin from Boswellia frereana;
b) exposing said resin to an organic solvent in a light-impermeable environment to provide an organic extraction mixture; c) removing any insoluble resin; and d) removing the organic solvent to produce Boswellia frereana extract. - View Dependent Claims (34, 35, 36, 37, 38)
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39. An extract obtained by the steps of:
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a) obtaining oleo-resin from Boswellia frereana;
b) exposing said oleo-resin to an organic solvent in a light impermeable environment to provide an organic extraction mixture; c) removing any insoluble resin; d) adding water to the organic extraction mixture to precipitate a solid triterpene fraction; and e) removing the organic solvent by evaporation to produce a Boswellia frereana extract.
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Specification