DEVICE FOR APPLYING AN OPHTHALMIC MEDICAMENT MIST

• US 20120179122A1
• Filed: 07/21/2010
• Published: 07/12/2012
• Est. Priority Date: 07/22/2009
• Status: Abandoned Application

• Current Assignee: Advanced Ophthalmic Pharma Ltd.
• Original Assignee: Advanced Ophthalmic Pharma Ltd.
• Inventors: Eilat, Eran, David, Robert, Altman, Joshua, Tshuva, Moshe
• Application Number:
  US13/384,842
• Publication Number:
  US 20120179122A1
• Time in Patent Office: Days
• US Class Current: 604/290
• CPC Class Codes: A61F 9/0026 Ophthalmic product dispenser attachments to facilitate positioning near the eye
• CPC Class Codes: A61M 11/00 Sprayers or atomisers specially adapted for therapeutic purposes in general B05B; aerosol containers B65D83/14
• CPC Class Codes: A61M 11/007 Syringe-type or piston-type sprayers or atomisers
• CPC Class Codes: A61M 15/0045 using multiple prepacked dosages on a same carrier, e.g. blisters
• CPC Class Codes: A61M 15/0048 the dosages being arranged in a plane, e.g. on diskettes
• CPC Class Codes: A61M 15/0061 using pre-packed dosages having an insert inside
• CPC Class Codes: A61M 2210/0612 Eyes
• CPC Class Codes: G02C 11/00 Non-optical adjuncts; Attachment thereof G02C7/16 takes precedence

Abstract

A device for applying an ophthalmologic medicament to a patient'"'"'s eye is disclosed. The device comprises spectacles defined by a frame and at least one lens; at least one container adapted for accommodating the ophthalmologic medicament; the container is incorporated into the frame; dosing mechanism adapted to control doses of the medicament; and at least one nozzle in a fluid interconnection with the medicament container; the nozzle is secured mechanically to the frame; the nozzle is adapted for providing a medicament mist flow. The nozzle is placed in front of a peripheral portion of a patient'"'"'s eye slot and adapted to provide the mist flow in front of the patient'"'"'s eye.

Claims

1-32. -32. (canceled)

33. A goggle-like dispenser of ophthalmologic medicaments comprising:

a single goggle held over the eye comprising;

a seal to prevent escape of the medicament mist within a confined volume surrounding the patient'"'"'s eye;

a mechanism for storing and mechanically delivering preservative-free medicaments; and

a dispenser to dispense a steady mist having droplet sizes on the range of approximately less than 50 microns that gently blanket and settle on the surface of the eye and that do not interfere with vision or irritate the eye.

34. The goggle-like dispenser of claim 33, further comprising:

at least one container adapted for accommodating ophthalmologic medicaments;

at least one nozzle placed in front of a peripheral portion of a patient'"'"'s eye slot, provided in a fluid interconnection with said container;

said nozzle mechanically secured to said dispenser body and adapted to provide said medicament mist flow;

wherein said nozzle is adapted to laterally provide said mist flow within said confined volume in a direct and-non-eye-impinging manner.

35. The goggle-like dispenser of claim 34, wherein said at least one container is incorporated within said frame or within said lens.

36. The goggle-like dispenser of claim 34, wherein said nozzle is mechanically secured to said frame or to said lens.

37. The goggle-like dispenser of claim 34, wherein said medicament is accommodated in said container in either a highly pressurized nitrogen-free state or-non-pressurized manner.

38. The goggle-like dispenser of claim 33, wherein said medicament mist is preservative-free.

39. The goggle-like dispenser of claim 38, wherein at least one of the following is being held true (a) said control mechanism is provided with a one-way dosing valve;

(b) said control mechanism regulates or meters one or more fluid'"'"'s parameters selected from a group consisting of dispensing-time protocol, droplet volume, fluid flux, droplet weight, batch unit, an any combination thereof; and

any combination thereof.

40. The goggle-like dispenser of claim 33, wherein said medicament mist is dispensed in such a manner that it remains in a dispersed state for a preset time scale, said time scale is between about 0.5 sec to about 5 sec, between about 5 sec to about 40 sec, between about 10 to about 50 sec, or between about 15 to about 60 sec.

41. The goggle-like dispenser of claim 33, further comprising a medicament heater and/or cooler.

42. The goggle-like dispenser of claim 33, wherein the at least one container is a plurality of microcontainers, in particular disposable microcontainers;

and said microcontainers are individually connectible in fluid-connection with said nozzle;

further wherein said microcontainers are fed by a feeding mechanism selected from the group consisting of a revolving nosepiece, a cartridge, a magazine, a clip, and any combination thereof.

43. The goggle-like dispenser of claim 42, comprising a connector adapted to consecutively or concurrently open said microcontainers and feed corresponding doses of said ophthalmic medicament into said nozzles.

44. The goggle-like dispenser of claim 33, further comprising at least one protective cover;

adapted to be folded over the eyecup in between uses to protect the eyecup from contamination from the outside environment;

further wherein said protective cover is a form-fitting wing.

45. A goggle-like Venturi nozzle dispenser of ophthalmologic medicaments comprising:

a single goggle held over the eye, comprising;

a seal to prevent escape of the medicament mist within a confined volume surrounding the patient'"'"'s eye;

a mechanism for storing and mechanically delivering preservative-free medicaments; and

a dispenser to dispense a steady mist flow having an outlet, in a fluid connection with at least one Bernoulli-type junction of multiple W conduits, W is an integer equal to or bigger than two;

said mist having droplet sizes on the range of approximately less than 50 microns that gently blanket and settle on the surface of the eye and that do not interfere with vision or irritate the eye.

46. The goggle-like Venturi nozzle dispenser of claim 45, wherein at least one of the following is being held true:

(a) said multiple W conduits provides a multiple conduits junction, said junction is selected from a group consisting of L-type, Y-type, T-type and X-type;

(b) the angle between the main longitudinal axis of two conduits is angle theta q, and wherein q is more than 0°

;

(c) angle q is about 90°

, and especially wherein q ranges between about 75°

to about 85°

; and

any combination thereof.

47. The goggle-like Venturi nozzle dispenser of claim 46, wherein at least one of the following is being held true (a) said at least one container is incorporated within said frame or within said lens;

(b) said fluid outlet is mechanically secured to said frame or to said lens;

(c) wherein said medicament is accommodated in said container in either a highly pressurized nitrogen-free state or non-pressurized manner;

(d) said medicament mist is preservative-free;

(e) said goggle-like Venturi nozzle dispenser further comprising a control mechanism adapted to control doses of said medicament; and

any combination thereof.

48. The goggle-like Venturi nozzle dispenser of claim 47, wherein said control mechanism is provided with a one-way dosing valve.

49. The goggle-like Venturi nozzle dispenser of claim 48, wherein said dosing is provided by one or more of a group consisting of predetermined time protocol, volume, flux, weight, batch unit, number of bursts, and any combination thereof.

50. The goggle-like Venturi nozzle dispenser of claim 47, wherein said medicament mist is dispensed in such a manner that it remains non-condensable matter for a preset time scale, said time scale is between about 1 to about 5 sec, between 5 sec to about 40 sec, between about 10 to about 50 sec, or between about 15 to about 60 sec.

51. The goggle-like Venturi nozzle dispenser of claim 47, further comprising at least one selected from a group consisting of (a) medicament heater and/or cooler;

(b) protective cover, especially a form-fitting wing;

said protective cover permanently or temporarily attached to said lens or dispenser body by mechanical attachment such as a hinge or equivalent, and effectively forming a seal when closed; and

any combination thereof.

52. The goggle-like Venturi nozzle dispenser of claim 47, wherein the mechanism for storing of the medicaments is a plurality of microcontainers;

said microcontainers are individually connectible in fluid-connection with said nozzle.

53. A method of dispensing ophthalmic medicaments comprising:

providing a goggle-like dispenser of ophthalmologic medicaments, comprising a single goggle held over the eye comprising;

a seal to prevent escape of the medicament mist within a confined volume surrounding the patient'"'"'s eye;

a mechanism for storing and mechanically delivering preservative-free medicaments; and

a dispenser to dispense a steady mist flow consisting of droplet sizes on the range of approximately less than 50 microns, said dispenser having an outlet, in a fluid connection with at least one Bernoulli-type junction of multiple W conduits, W is an integer equal to or bigger than two;

filling said container with said ophthalmic medicament;

placing said device on the patient; and

,

facilitating a flow of a mist or vapor medicament into the confined volume defined between the patient'"'"'s eye and the lens;

wherein said facilitating is performed in a manner that gently blanket and settle on the surface of the eye and that do not interfere with vision or irritate the eye.

54. A method of dispensing ophthalmic medicaments comprising:

providing a goggle-like dispenser of ophthalmologic medicaments, comprising a single goggle held over the eye comprising;

a seal to prevent escape of the medicament mist within a confined volume surrounding the patient'"'"'s eye;

a mechanism for storing and mechanically delivering preservative-free medicaments; and

a dispenser to dispense a steady mist consisting of droplet sizes on the range of approximately less than 50 microns;

filling said container with said ophthalmic medicament;

placing said device on the patient; and

,

facilitating a flow of a mist or vapor medicament into the confined volume defined between the patient'"'"'s eye and the lens;

wherein said facilitating is performed in a manner that gently blanket and settle on the surface of the eye and that do not interfere with vision or irritate the eye.