HEART VALVE REMODELING

• US 20120179184A1
• Filed: 09/15/2010
• Published: 07/12/2012
• Est. Priority Date: 09/15/2009
• Status: Abandoned Application

• Current Assignee: Transcardia Ltd.
• Original Assignee: Transcardia Ltd.
• Inventors: Orlov, Boris
• Application Number:
  US13/496,226
• Publication Number:
  US 20120179184A1
• Time in Patent Office: Days
• US Class Current: 606/170
• CPC Class Codes: A61B 17/0643 with separate closing member, e.g. for interlocking with staple
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable or resorptive
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/00783 Valvuloplasty
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/0641 having at least three legs as part of one single body
• CPC Class Codes: A61B 90/02 Devices for expanding tissue, e.g. skin tissue implements for holding wounds open, surgical tractors A61B17/02; implantable mammary prosthesis A61F2/12; dilators A61M29/00
• CPC Class Codes: A61F 2/2463 Implants forming part of the valve leaflets

Abstract

A device for remodeling atrioventricular valve leaflets including one or more stretching members and one or more leaflet engaging elements, wherein each stretching member includes at least one leaflet engaging element, the leaflet engaging elements are configured to penetrate a valve leaflet, and the stretching members are configured to be positioned externally to a plane of the leaflet when the leaflet engaging elements have penetrated a valve leaflet. A method for remodeling atrioventricular valve leaflets including inserting one or more leaflet engaging elements into an atrioventricular valve leaflet, and using stretching members positioned externally to a plane of the leaflet to apply a stretching force on the atrioventricular valve leaflet. Related apparatus and methods are also described.

Claims

1. A device for remodeling atrioventricular valve leaflets comprising one or more stretching members and one or more leaflet engaging elements, wherein:

each stretching member comprises at least one leaflet engaging element;

the leaflet engaging elements are configured to penetrate a valve leaflet; and

the stretching members are configured to be positioned externally to a plane of the leaflet when the leaflet engaging elements have penetrated a valve leaflet.

2. The device of claim 1 in which the stretching members are configured to exert a stretching force on the valve leaflet by pushing on the leaflet engaging elements.

3. The device of claim 1 in which the stretching members are configured to exert a stretching force on the valve leaflet by pulling on the leaflet engaging elements.

6. The device of claim 1 in which the leaflet engaging element comprises a blade.

7. The device of claim 1 in which the leaflet engaging elements are configured to engage the valve leaflet substantially in a shape which is one of a group including:

a circle;

an oval;

a closed curve;

two parallel lines; and

a plurality of concentric circles.

10. The device of claim 1 in which the leaflet engaging elements are configured to penetrate the leaflet over an area comprising about 20% to 80% of an area of the leaflet.

18. The device of claim 1 and further comprising a mesh comprising a shape configured for covering at least holes made by the leaflet engaging elements.

19. The device of claim 1 and further comprising a counter plate, the counter plate comprising blades for cutting into the valve leaflet, the blades configured to cut into the valve leaflet within an area encompassed by the stretching members.

21. The device of claim 19, in which at least one of the one or more stretching members is connected to a stem, and the counter plate further comprises a hole for sliding over the stem.

4-5. -5. (canceled)

8-9. -9. (canceled)

11-17. -17. (canceled)

20. (canceled)

22. (canceled)

23. A method for remodeling atrioventricular valve leaflets comprising:

inserting one or more leaflet engaging elements into an atrioventricular valve leaflet; and

using stretching members positioned externally to a plane of the leaflet to apply a stretching force on the atrioventricular valve leaflet.

24. The method of claim 23 in which the stretching force is applied by forcing apart the leaflet engaging elements.

26. The method of claim 23 in which the stretching force is applied by pulling on the leaflet engaging elements.

27. The method of claim 23 in which the stretching force is enough to cause elastic stretching of the leaflet, and less than enough to cause plastic deformation of the leaflet.

28. The method of claim 23 in which the stretching force is enough to cause plastic deformation of the leaflet.

29. The method of claim 23 in which the leaflet engaging elements are left in the atrioventricular valve leaflet and the forcing continues over a period of time.

32. The method of claim 23 and further comprising using stretching fingers attached to the leaflet engaging elements for forcing apart the leaflet engaging elements.

34. The method of claim 23 and further comprising cutting holes into the atrioventricular valve leaflet.

35. The method of claim 34 and further comprising covering holes made by the cutting with a mesh.

36. The method of claim 23 and further comprising bringing the one or more leaflet engaging elements up to an in-vivo atrioventricular valve leaflet via a catheter.

25. (canceled)

30-31. -31. (canceled)

33. (canceled)

37. (canceled)

38. A device for remodeling atrioventricular valve leaflets comprising:

one or more means for grasping one or more locations on an atrioventricular valve leaflet; and

means, positioned externally to a plane of the leaflet, for applying a stretching force between the locations.

39. The apparatus of claim 38 and further including means for cutting holes into the atrioventricular valve leaflet.

40. The apparatus of claim 39 and further including means for covering up the holes in the atrioventricular valve leaflet.