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VAGUS NERVE STIMULATION METHOD

  • US 20120191158A1
  • Filed: 04/03/2012
  • Published: 07/26/2012
  • Est. Priority Date: 03/29/2006
  • Status: Active Grant
First Claim
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1. A method of treating a medical condition in a patient having a brain, a vagus nerve, and a heart that generates a cardiac signal having a QRS wave portion, the method comprising:

  • identifying a select portion of the QRS wave portion of the patient'"'"'s cardiac signal;

    after identifying the select portion of the QRS wave portion and before identifying a select portion of a next sequential QRS wave portion, generating at least one microburst, the-at least one microburst being patterned and comprising 2 to 20 electrical pulses, adjacent ones of the electrical pulses being separated from one another by an interpulse interval of less than about 40 milliseconds; and

    delivering the at least one microburst directly to a selected location on the vagus nerve of the patient, the at least one microburst delivered to the vagus nerve evoking a response in the brain of the patient, wherein the pulses of the at least one microburst are spaced apart to simulate endogenous afferent activity occurring at a particular time in the cardiac signal and enhance a vagal evoked potential evoked in the brain.

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