NANO PARTICLE TRACKING DEVICE, CHANNEL STRUCTURE OF THE NANO PARTICLE TRACKING DEVICE, AND METHOD OF FABRICATING THE CHANNEL STRUCTURE OF THE NANO PARTICLE TRACKING DEVICE

• US 20120194811A1
• Filed: 06/15/2011
• Published: 08/02/2012
• Est. Priority Date: 01/27/2011
• Status: Active Grant

• Current Assignee: Samsung Electronics Co. Ltd.
• Original Assignee: Samsung Electronics Co. Ltd.
• Inventors: LEE, June-young, CHO, Seong-ho, KIM, Su-hyeon, JEONG, Hee-jeong
• Granted Patent: US 8,724,105 B2
• Time in Patent Office: Days
• US Class Current: 356/244
• CPC Class Codes: B01L 3/502707 characterised by the manufacture of the container or its components by shaping or joining plastic parts B29C59/00, B29C65/00; by laminating B32B37/00; manufacture of microstructural devices in general B81C
• CPC Class Codes: B32B 2535/00 Medical equipment, e.g. bandage, prostheses or catheter
• CPC Class Codes: B32B 37/065 resulting in the laminate being partially bonded B32B37/0076 takes precedence
• CPC Class Codes: B32B 37/12 characterised by using adhesives
• CPC Class Codes: B32B 38/06 Embossing
• CPC Class Codes: B82Y 15/00 Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
• CPC Class Codes: G01N 1/10 in the liquid or fluent state burettes, pipettes B01L3/02; sampling of ground water E02D1/06; metering by volume of fluids or fluent solid material G01F11/00, G01F13/00
• CPC Class Codes: G01N 21/554 detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance
• CPC Class Codes: G01N 21/645 Specially adapted constructive features of fluorimeters
• CPC Class Codes: Y10S 977/953 Detector using nanostructure
• CPC Class Codes: Y10S 977/957 Of chemical property or presence
• CPC Class Codes: Y10S 977/958 Of biomolecule property

Abstract

A nano particle tracking device includes a channel structure. The channel structure of the nano particle tracking device includes a pair of microchannels in which a specimen including nano particles is accommodated and which face each other, at least one nano channel which is between the pair of microchannels, which connects the pair of microchannels to each other and through which the nano particles in the specimen are moved, and a nano grating below the nano channel and crossing the nano channel perpendicularly.

Claims

1. A channel structure of a nano particle tracking device, comprising:

a pair of microchannels in which a specimen including nano particles is accommodated, and which face each other;

at least one nano channel which is between the pair of microchannels, which connects the pair of microchannels to each other, and through which the nano particles in the specimen are moved between the pair of microchannels; and

a nano grating below the nano channel and crossing the nano channel perpendicularly.

2. The channel structure of claim 1, wherein the nano grating comprises a pattern of a plurality of parallel opaque bars which are arranged at regular intervals.

3. The channel structure of claim 2, wherein a thickness of the nano grating is greater than a skin depth of a material of the nano grating.

4. The channel structure of claim 2, wherein a distance between adjacent parallel opaque bars is less than a wavelength of visible light.

5. The channel structure of claim 1, further comprising:

a first transparent substrate;

a channel forming layer on the first transparent substrate; and

a second transparent substrate on the channel forming layer, the channel forming layer between the first and second transparent substrates.

6. The channel structure of claim 5, wherein

the pair of microchannels extends through the channel forming layer and into the first transparent substrate,

the nano channel is on an upper surface of the channel forming layer between the pair of microchannels, and

the nano grating is on a top surface of the first transparent substrate between the pair of microchannels, and is covered by the channel forming layer.

7. The channel structure of claim 5, further comprising via holes through which the specimen is provided to the pair of microchannels, and connected to at least one of two end portions of each of the pair of microchannels.

8. The channel structure of claim 7, wherein the via holes extend completely through at least the first transparent substrate or completely through at least the second transparent substrate.

9. The channel structure of claim 1, further comprising:

a first transparent substrate;

a channel forming layer on the first transparent substrate;

a junction layer on the channel forming layer, the channel forming layer between the first transparent substrate and the junction layer; and

a second transparent substrate on the junction layer.

10. The channel structure of claim 9, wherein

the pair of microchannels extends through the junction layer, the channel forming layer, and into the first transparent substrate,

the nano channel is on an upper surface of the channel forming layer between the pair of microchannels, and

the nano grating is on a top surface of the first transparent substrate between the pair of microchannels, and is covered by the channel forming layer.

11. The channel structure of claim 9, further comprising via holes through which the specimen is provided to the pair of microchannels, and connected to at least one of two end portions of each of the pair of microchannels.

12. The channel structure of claim 11, wherein the via holes extend completely through the second transparent substrate and the junction layer, or completely through at least the first transparent substrate.

13. The channel structure of claim 9, wherein the junction layer comprises polysilicon.

14. The channel structure of claim 13, wherein the junction layer includes an oxide layer which is an oxidized surface of the polysilicon.

15. A nano particle tracking device comprising:

the channel structure of claim 1; and

further comprising a photodetector opposite the nano channel with respect to the nano grating in a region overlapping the nano channel.

16. The nano particle tracking device of claim 15, further comprising a band pass filter between the channel structure and the photodetector.

17. The nano particle tracking device of claim 15, wherein

the channel structure further comprises a plurality of nano channels, and

further comprising one photodetector for each of the nano channels.

18. A method of fabricating a channel structure, the method comprising:

forming a nano grating having a pattern of a plurality of parallel opaque bars arranged at regular intervals, on a top surface of a first transparent substrate;

forming a channel forming layer on the first transparent substrate and covering the nano grating;

forming a junction layer on the channel forming layer;

forming nano channels in a direction perpendicular the nano grating by patterning portions of the junction layer corresponding to the nano grating;

forming a pair of microchannels which is connected to end portions of each of the nano channels by partially etching the junction layer, the channel forming layer, and the first transparent substrate; and

bonding a second transparent substrate directly onto the junction layer.

19. The method of claim 18, further comprising, after the channel forming layer is formed, planarizing a top surface of the channel forming layer.

20. The method of claim 18, wherein the junction layer comprises polysilicon.

21. The method of claim 20, further comprising, before the second transparent substrate is bonded onto the junction layer, forming an oxide layer covering the junction layer by oxidizing a surface of the junction layer

22. The method of claim 18, wherein a thickness of the nano grating is greater than a skin depth of a material of the nano grating.

23. The method of claim 18, wherein a distance between adjacent parallel opaque bars is less than a wavelength of visible light.

24. The method of claim 18, further comprising forming via holes through the second transparent substrate and the junction layer, which are connected to an end portion of each of the microchannels.

25. The method of claim 18, further comprising forming via holes through the first transparent substrate, which are connected to an end portion of each of the microchannels.

26. A method of fabricating a channel structure, the method comprising:

forming a nano grating having a pattern of a plurality of parallel opaque bars arranged at regular intervals on a top surface of a first transparent substrate;

forming a channel forming layer on the first transparent substrate and covering the nano grating;

forming nano channel in a direction perpendicular to the nano grating by patterning portion of a top surface of the channel forming layer corresponding to the nano grating, such that a thickness of the channel forming layer corresponding to the nano channel is smaller than remaining portions of the channel forming layer;

forming a pair of microchannels which is connected to end portions the nano channel by partially etching the channel forming layer and the first transparent substrate; and

bonding a second transparent substrate directly onto the channel forming layer.

27. The method of claim 26, further comprising, forming via holes through at least the first transparent substrate or through at least the second transparent substrate, the via holes connected to an end portion of each of the microchannels.