APPARATUS, SYSTEM AND METHODS FOR PHOTOACOUSTIC DETECTION OF DEEP VEIN THROMBOSIS
First Claim
1. A system for detection of deep vein thrombosis in a patient, the system comprising:
- a first light source configured to emit light at a first wavelength;
a second light source configured to emit light at a second wavelength, wherein the first and second light sources are configured to be directed on the skin of the patient to produce a photo acoustic signal which is correlated to an amount of absorbance of the first and second wavelengths by a target region of the patient'"'"'s tissue;
an acoustic transducer for detecting the photo acoustic signal;
wherein the acoustic transducer generates an electrical signal resulting from the photo acoustic signal;
a data converter for converting the electrical signal into a digital signal; and
a processor configured to analyze the digital signal to detect the presence of deep vein thrombosis within the target region.
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Accused Products
Abstract
Embodiments of the invention provide apparatus, systems and methods for the detection of deep vein thrombosis (DVT) using photoacoustic measurement of hemoglobin in different states of oxgyenation within tissue. One embodiment of a system for DVT detection comprises at least a first and second light source that emit light at first and second wavelengths, an acoustic transducer, a data converter and a processor. The first and second light sources are directed on the patient'"'"'s skin to produce a photoacoustic signal (PS) correlated to an amount of absorbance of the first and second wavelengths by a target region of tissue beneath the patient'"'"'s skin. The acoustic transducer detects the PS and transduces it into an electrical signal which is correlated to the PS. The data converter converts the electrical signal into a digital signal which is analyzed by the processor to detect the presence of DVT within the target region.
29 Citations
50 Claims
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1. A system for detection of deep vein thrombosis in a patient, the system comprising:
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a first light source configured to emit light at a first wavelength; a second light source configured to emit light at a second wavelength, wherein the first and second light sources are configured to be directed on the skin of the patient to produce a photo acoustic signal which is correlated to an amount of absorbance of the first and second wavelengths by a target region of the patient'"'"'s tissue; an acoustic transducer for detecting the photo acoustic signal;
wherein the acoustic transducer generates an electrical signal resulting from the photo acoustic signal;a data converter for converting the electrical signal into a digital signal; and a processor configured to analyze the digital signal to detect the presence of deep vein thrombosis within the target region. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. A system for detection of deep vein thrombosis in a patient, the system comprising:
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a first light source configured to emit substantially monochromatic light at a first wavelength; a second light source configured to emit substantially monochromatic light at a second wavelength, wherein the first and second light sources are configured to be directed on the skin of the patient to produce a photo acoustic signal which is correlated to an amount of absorbance of the first and second wavelengths by a target region of the patient'"'"'s tissue beneath the skin; an acoustic transducer for detecting the photo acoustic signal;
wherein the acoustic transducer generates an electrical signal resulting from the photo acoustic signal;a data converter for converting the electrical signal into a digital signal; and a processor configured to analyze the digital signal to detect the presence of deep vein thrombosis within the target region.
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25. A system for detection of a tissue condition in a patient, the system comprising:
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a first light source configured to emit light at a first wavelength; a second light source configured to emit light at a second wavelength, wherein the first and second light sources are configured to be directed on the skin of the patient to produce a photo acoustic signal which is correlated to an amount of absorbance of the first and second wavelengths by a target region of the patient'"'"'s tissue; an acoustic transducer for detecting the photo acoustic signal;
wherein the acoustic transducer generates an electrical signal resulting from the photo acoustic signal;a data converter for converting the electrical signal into a digital signal; and a processor configured to analyze the digital signal to detect the presence of the tissue condition within the target region. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33, 34)
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35. A method for detection of deep vein thrombosis in a patient, the method comprising:
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emitting light at a first and second wavelength onto the skin of a patient at a target tissue region, generating a photo acoustic signal in the target region, the photo acoustic signal being correlated to an amount of absorbance of the first and second wavelengths; transducing the photo acoustic signal into an electrical signal; and analyzing the electrical signal to detect the presence of deep vein thrombosis within the target region. - View Dependent Claims (36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50)
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Specification