Injection Arrangement for a Flowable Drug

• US 20120209249A1
• Filed: 06/18/2010
• Published: 08/16/2012
• Est. Priority Date: 06/19/2009
• Status: Abandoned Application

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Basso, Nils, Nagel, Thomas, Richter, Rene, Witt, Robert
• Application Number:
  US13/377,155
• Publication Number:
  US 20120209249A1
• Time in Patent Office: Days
• US Class Current: 604/506
• CPC Class Codes: A61M 2005/14513 with secondary fluid driving or regulating the infusion
• CPC Class Codes: A61M 5/1486 the bags being substantially completely surrounded by fluid
• CPC Class Codes: A61M 5/282 by compression of deformable ampoule or carpule wall
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules

Abstract

The invention refers to an injection arrangement (1) comprising a replaceable container cartridge (2) for a flowable drug (5), the container cartridge (2) comprising a deformable bag (4) arranged inside and sealed against a rigid outer casing (3), the deformable bag (4) being arranged for holding the flowable drug (5) and in fluid communication with an outlet (6), the rigid outer casing (3) fillable by a displacement fluid (7) for displacing the deformable bag (4), the injection arrangement (1) further comprising a reservoir (8) for the displacement fluid (7) and a pump (9) for pumping the displacement fluid (7) from the reservoir (8) into the rigid outer casing (3) and/or from the rigid outer casing (3) into the reservoir (8) via a fluid channel (10).

Claims

1. Injection arrangement comprising a replaceable container cartridge for a flowable drug, the container cartridge comprising a deformable bag arranged inside and sealed against a rigid outer casing, the deformable bag being arranged for holding the flowable drug and in fluid communication with an outlet, the rigid outer casing fillable by a displacement fluid for displacing the deformable bag the injection arrangement further comprising a reservoir holding the displacement fluid and a pump for pumping the displacement fluid from the reservoir into the rigid outer casing and/or from the rigid outer casing into the reservoir via a fluid channel, wherein the displacement fluid is a liquid.

2. Injection arrangement according to claim 1, characterized in that the outlet comprises a hollow needle.

3. Injection arrangement according to claim 1, characterized in that the outlet comprises a jet nozzle.

4. Injection arrangement according to claim 1, characterized in that the displacement fluid comprises oil and/or water.

5. Injection arrangement according to claim 1, characterized in that the deformable bag is attached at an end of the rigid outer casing opposite the outlet.

6. Injection arrangement according to claim 1, characterized in that the deformable bag is inserted into the rigid outer casing through an open outlet end of the rigid outer casing, wherein the deformable bag is attached to a closure member for sealing the open outlet end, the closure member having a fluid passage for allowing fluid communication between the deformable bag and the outlet.

7. Injection arrangement according to claim 6, characterized in that the closure member is glued or welded or crimped onto the open outlet end.

8. Injection arrangement according to claim 1, characterized in that the deformable bag comprises silicone.

9. Injection arrangement according to claim 1, characterized in that the pump is a piston pump comprising an electric motor wherein an amount of the displacement fluid pumped from the reservoir into the rigid outer casing may be determined based at least in part on the number of motor rotations.

10. Injection arrangement according to claim 1, characterized in that a flux sensor is arranged between the pump and the rigid outer casing.

11. Injection arrangement according to claim 1, characterized in that the reservoir is integrated with the pump in a pump module.

12. Injection arrangement according to claim 1, characterized in that the reservoir is refillable.

13. Use of an injection arrangement according to claim 1 for delivering a flowable drug of the group Insulin, Heparin, Lovenox, human growth hormones, peptide hormones, analgetics and vaccines.

14. Method for operating an injection arrangement, the injection arrangement comprising a replaceable container cartridge for a flowable drug, the container cartridge comprising a deformable bag arranged inside and sealed against a rigid outer casing, the deformable bag being arranged for holding the flowable drug and in fluid communication with an outlet, the rigid outer casing fillable by a displacement fluid for displacing the deformable bag, the injection arrangement further comprising a reservoir for the displacement fluid and a pump, the method comprising the step of pumping the displacement fluid from the reservoir into the rigid outer casing and/or from the rigid outer casing into the reservoir via a fluid channel, characterized in that the displacement fluid used is a liquid.

15. Method according to claim 14, characterized in that the displacement fluid comprises oil and/or water.

16. Method according to claim 14, characterized in that a flux sensor arranged between the pump (9) and the rigid outer casing is used for setting and controlling a dose of the flowable drug to be injected by measuring the flux of the displacement fluid.