SLEEP AID COMPOSITION AND METHOD

• US 20120214793A1
• Filed: 11/29/2010
• Published: 08/23/2012
• Est. Priority Date: 11/09/2010
• Status: Active Grant

• Current Assignee: Carl Anthony Forest
• Original Assignee: Carl Anthony Forest
• Inventors: Forest, Carl A.
• Granted Patent: US 8,741,888 B2
• Time in Patent Office: Days
• US Class Current: 514/211.13
• CPC Class Codes: A61P 25/00 Drugs for disorders of the nervous system
• CPC Class Codes: C23C 14/3407 Cathode assembly for sputtering apparatus, e.g. Target
• CPC Class Codes: C23C 14/352 using more than one target C23C14/56 takes precedence
• CPC Class Codes: C23C 16/50 using electric discharges generation and control of plasma in discharge tubes for surface treatment H01J37/32, H01J37/34
• CPC Class Codes: H01J 37/34 operating with cathodic sputtering H01J37/36 takes precedence ; methods of cathodic sputtering C23C14/34
• CPC Class Codes: H01J 37/3405 Magnetron sputtering
• CPC Class Codes: H01J 37/3417 Arrangements
• CPC Class Codes: H01J 37/3435 Target holders (includes backing plates and endblocks)
• CPC Class Codes: H01J 37/3452 Magnet distribution
• CPC Class Codes: H01J 37/3458 Electromagnets in particular for cathodic sputtering apparatus electromagnets in general H01F7/06

Abstract

A sleep composition including zolpidem and quetiapine in combination provides a healthy sleep pattern allowing the user to get seven or eight hours sleep. The amount of each ingredient in the combination is lower than the amount usually needed to provide this amount of sleep when the ingredients are being used alone.

Claims

1. A pill comprising:

a composition comprising a first compound and a second compound, wherein;

said first compound comprises zolpidem;

said second compound comprises quetiapine; and

wherein said composition comprises from 1 mg to 10 mg of said zolpidem combined with from 5 to 45 mg of said quetiapine.

2. A pill as in claim 1 wherein said composition consists essentially of said zolpidem and said quetiapine.

3. A pill as in claim 2 wherein said composition comprises less than 5 mg of said zolpidem.

4. A pill as in claim 2 wherein said composition comprises from 10 mg to 45 mg of said quetiapine.

5. A pill as in claim 2 wherein said composition comprises less than 25 mg of said quetiapine.

6. A pill comprising:

a composition comprising zolpidem and quetiapine, said zolpidem and said quetiapine included in said composition in amounts wherein said quetiapine essentially eliminates the side affect of said zolpidem which hinders sleep without using said zolpidem.

7. A pill as in claim 6 wherein said zolpidem and said quetiapine are included in said composition in amounts wherein said zolpidem essentially eliminates the side effect of said quetiapine which results in weight gain or the side effect of quetiapine that results in somnolence.

8. A pill comprising:

a composition comprising essentially of zolpidem and quetiapine, said zolpidem included in said composition in an amount less than an amount that leads to tolerance to or addiction to said zolpidem and said quetiapine included in said composition in an amount less than an amount that leads to tolerance to or addiction to said quetiapine, said quetiapine being in immediate release form, said pill and said composition not including a 4-acylaminopyridine derivative, an HMG Coenenzyme A Reductase (HMGCR) modulating agent, a melanocortin receptor, an angiotensin modulator, a peroxisome proliferator-activated receptor (PPAR) agent, lithium or quetiapine in an extended release, delayed extended release or delayed pulsed release form.

9. A method of promoting sleep in a human, said method comprising:

preparing a composition consisting of a first compound comprising zolpidem and a second compound comprising quetiapine, said zolpidem and said quetiapine included in said composition in an amount sufficient to prevent tolerance to and addiction to said zolpidem; and

orally or parenterally administering said composition to a human prior to a sleep period for a period longer than two months.

10. A method as in claim 9 wherein the entire amount of said zolpidem and said quetiapine are provided in said composition only in their immediate release forms.

11. A combination of pills comprising:

a first pill comprising a first composition comprising zolpidem and quetiapine; and

a second pill comprising a second composition comprising zolpidem and quetiapine;

wherein the ratio of the amount of zolpidem in milligrams to the amount of quetiapine in milligrams in said first pill is a first ratio and the ratio of the amount of zolpidem in milligrams to the amount of quetiapine in milligrams in second pill is a second ratio different from said first ratio.

12. A combination of pills as in claim 11 wherein said first ratio differs from said second ratio by 5% or more.

13. A combination of pills as in claims 11 wherein said first ratio is from 1/50 to 1/5.

14. A combination of pills as in claim 11 wherein said second ratio is from 1/4 to 2.

15. A combination of pills as in claim 11 where in said first ratio is from 1/50 and 1/5 and said second ratio is from 1/4 to 2.

16. A combination of pills as in claim 11 and further including a third pill comprising zolpidem and quetiapine where the ratio of said zolpidem in milligrams to said quetiapine in milligrams in said third pill is between said first ratio and said second ratio.

17. A method of marketing a sleeping aid, said method comprising:

providing a first pill comprising a first composition comprising zolpidem and quetiapine; and

providing a second pill comprising a second composition comprising zolpidem and quetiapine;

wherein the ratio of the amount of zolpidem in milligrams to the amount of quetiapine in milligrams in said first pill is a first ratio and the ratio of the amount of zolpidem in milligrams to the amount of quetiapine in milligrams in second pill is a second ratio different from said first ratio.