METHODS AND APPARATUSES FOR DETECTING OCCLUSIONS IN AN AMBULATORY INFUSION PUMP

• US 20120215169A1
• Filed: 04/18/2012
• Published: 08/23/2012
• Est. Priority Date: 10/29/1998
• Status: Active Grant

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Inventors: MOBERG, SHELDON B., Hanson, Ian B., Talbot, Cary D.
• Granted Patent: US 8,617,110 B2
• Time in Patent Office: Days
• US Class Current: 604/151
• CPC Class Codes: A61M 2005/14264 with means for compensating influence from the environment
• CPC Class Codes: A61M 2005/16863 Occlusion detection
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/332 Force measuring means
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/70 with testing or calibration facilities
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066
• CPC Class Codes: A61M 5/16854 by monitoring line pressure
• CPC Class Codes: Y02A 90/10 Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

An improved pump, reservoir and reservoir piston are provided for controlled delivery of fluids. A motor is operably coupled to a drive member, such as a drive screw, which is adapted to advance a plunger slide in response to operation of the motor. The plunger slide is removably coupled to the piston. Methods, systems, and articles of manufacture for automatically detecting an occlusion in a medication infusion pump are provided. The electrical current to an infusion pump may be measured. Based on measurements of one or more variables, such as force, the infusion pump detects whether there is an occlusion in the system. The methods of detecting occlusions may be dynamic.

Claims

1. An infusion pump for infusing fluid from a reservoir into a body of a user, the infusion pump comprising:

a housing;

a motor contained within the housing;

one or more drive train components coupled to the motor within the housing and configured to move in response to the motor to deliver fluid from the reservoir through a fluid path into the body of the user;

a sensor that periodically measures the value of a parameter associated with the motor or one of the drive train components during delivery of a current pulse of infusion fluid to obtain a series of measurements; and

a processor contained within the housing, wherein the processor determines a peak value of the series of measurements, selects a second value later than the peak value within the series of measurements, calculates a difference between the peak value and the second value, and declares an occlusion has occurred if the difference exceeds a threshold value.

2. The infusion pump of claim 1, wherein the sensor measures the value of the parameter continuously during delivery of the pulse of infusion fluid.

3. The infusion pump of claim 1, wherein the processor dynamically updates the threshold value based on measurements of the value of said parameter during delivery of at least one previous pulse of infusion fluid before the delivery of the current pulse of infusion fluid.

4. An infusion pump for infusing fluid from a reservoir into a body of a user, the infusion pump comprising:

a housing;

a motor contained within the housing;

one or more drive train components coupled to the motor within the housing and configured to move in response to the motor to deliver fluid from the reservoir through a fluid path into the body of the user;

a sensor that periodically measures the value of a parameter associated with the motor or one of the drive train components during delivery of a current pulse of infusion fluid to obtain a series of measurements; and

a processor contained within the housing, wherein the processor determines a peak value of the series of measurements, selects a second value later than the peak value within the series of measurements, calculates a difference between the peak value and the second value, increments a counter when the difference exceeds a threshold value, restarts the counter when the difference is below the threshold value, and declares an occlusion has occurred when the counter exceeds an occlusion-detection count.

5. The infusion pump of claim 4, wherein the sensor measures the value of the parameter continuously during delivery of the pulse of infusion fluid.

6. The infusion pump of claim 4, wherein the processor dynamically updates the threshold value based on measurements of the value of said parameter during delivery of at least one previous pulse of infusion fluid before the delivery of the current pulse of infusion fluid.

7. An infusion pump for infusing fluid from a reservoir into a body of a user, the infusion pump comprising:

a housing;

a motor contained within the housing;

one or more drive train components coupled to the motor within the housing and configured to move in response to the motor to deliver fluid from the reservoir through a fluid path into the body of the user;

a sensor that periodically measures the value of a parameter associated with the motor or one of the drive train components during delivery of a current pulse of infusion fluid to obtain a series of measurements; and

a processor contained within the housing, wherein the processor determines a peak value of the series of measurements, selects a second value later than the peak value within the series of measurements, calculates a current difference between the peak value and the second value, retrieves a previous difference between a previous peak value and a previous second value later than the previous peak value calculated based on measurements of the value of the parameter during delivery of a previous pulse of infusion fluid, calculates an average difference using the previous difference and the current difference, and declares an occlusion has occurred if the average difference exceeds a threshold value.

8. The infusion pump of claim 7, wherein, in calculating the average difference, the processor further uses a second previous difference calculated based on measurements of the value of the parameter during delivery of a second previous pulse of infusion fluid.

9. The infusion pump of claim 8, wherein the processor calculates the average difference based on measurements of the value of the parameter during delivery of three consecutive pulses of infusion fluid.

10. The infusion pump of claim 7, wherein the processor dynamically updates the threshold value based on measurements of the value of said parameter during delivery of at least one previous pulse of infusion fluid before the delivery of the current pulse of infusion fluid.

11. An infusion pump for infusing fluid from a reservoir into a body of a user, the infusion pump comprising:

a housing;

a motor contained within the housing;

one or more drive train components coupled to the motor within the housing and configured to move in response to the motor to deliver fluid from the reservoir through a fluid path into the body of the user;

a sensor that periodically measures the value of a parameter associated with the motor or one of the drive train components during delivery of a current pulse of infusion fluid to obtain a series of measurements; and

a processor contained within the housing, wherein the processor determines a peak value of the series of measurements, selects a second value later than the peak value within the series of measurements, selects a third value later than the peak value within the series of measurements, calculates a slope of a line using the second and third values; and

determines whether an occlusion has occurred by comparing the slope to a threshold value.

12. The infusion pump of claim 11, wherein the processor declares an occlusion has occurred if the slope exceeds the threshold value.

13. The infusion pump of claim 11, wherein the processor determines whether an occlusion has occurred based upon a comparison of the slope to a predetermined percentage of the threshold value.

14. The infusion pump of claim 11, wherein the threshold value is predetermined for the infusion pump.

15. The infusion pump of claim 11, wherein the processor dynamically updates the threshold value based on measurements of the value of said parameter during delivery of at least one previous pulse of infusion fluid before the delivery of the current pulse of infusion fluid.

16. An infusion pump for infusing fluid from a reservoir into a body of a user, the infusion pump comprising:

a housing;

a motor contained within the housing;

one or more drive train components coupled to the motor within the housing and configured to move in response to the motor to deliver fluid from the reservoir through a fluid path into the body of the user;

a sensor that periodically measures the value of a parameter associated with the motor or one of the drive train components during delivery of a current pulse of infusion fluid to obtain a series of measurements; and

a processor contained within the housing, wherein the processor determines a peak value of the series of measurements, selects a second value later than the peak value within the series of measurements, calculates a current difference between the peak value and the second value, retrieves a first previous difference between a first previous peak value and a first previous second value later than the first previous peak value calculated based on measurements of the value of said parameter during delivery of a first previous pulse of infusion fluid, retrieves a second previous difference between a second previous peak value and a second previous second value later than the second previous peak value calculated based on measurements of the value of said parameter during delivery of a second previous pulse of infusion fluid, calculates an average difference using the first previous difference and the second previous difference, and declares an occlusion has occurred if the current difference exceeds the average difference.

17. The infusion pump of claim 16, wherein, in calculating the average difference, the processor further uses a third previous difference calculated based on measurements of the value of the parameter during delivery of a third previous pulse of infusion fluid.

18. The infusion pump of claim 17, wherein the processor calculates the average difference based on measurements of the value of said parameter during delivery of three consecutive pulses of infusion fluid.

19. The infusion pump of claim 17, wherein the processor calculates the average difference based on measurements of the values of said parameter during delivery of three consecutive pulses of infusion fluid that are at least three pulses prior to the delivery of the current pulse of infusion fluid.