OPTICAL BLOOD GLUCOSE DETECTING APPARATUS AND OPERATING METHOD THEREOF

• US 20120238843A1
• Filed: 03/15/2012
• Published: 09/20/2012
• Est. Priority Date: 03/15/2011
• Status: Active Grant

• Current Assignee: Crystalvue Medical Corporation
• Original Assignee: Crystalvue Medical Corporation
• Inventors: YEN, Meng-Shin, Wang, William, Chou, Chung-Cheng, Chuang, Chung-Ping
• Granted Patent: US 9,211,089 B2
• Time in Patent Office: Days
• US Class Current: 600/316
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters

Abstract

An optical blood glucose detecting apparatus and an operating method thereof are disclosed. The optical blood glucose detecting apparatus includes a detecting module, an assisting and strengthening module, and a data processing module. The detecting module provides an incident optical signal passing through a detected portion of skin surface into a skin interstitial fluid, captures a blood glucose optical reflection message of the skin interstitial fluid, and it interferes the blood glucose optical reflection message and the incident optical signal to generate a detected data. The assisting and strengthening module provides a physical or chemical effect on a tissue region under the detected portion to strengthen the blood glucose optical reflection message. The data processing module processes the detected data to determine a blood glucose concentration.

Claims

1. An optical blood glucose detecting apparatus, comprising:

a detecting module, for providing an incident optical signal to pass through a detected portion of a skin surface into a skin interstitial fluid, and capturing a blood glucose optical reflection message of the skin interstitial fluid, and interfering the blood glucose optical reflection message and the incident optical signal to generate a detected data;

an assisting and strengthening module, for providing a physical effect or a chemical effect on a tissue region under the detected portion to strengthen the blood glucose optical reflection message; and

a data processing module, coupled to the detecting module and the assisting and strengthening module, for processing the detected data to determine a blood glucose concentration.

2. The optical blood glucose detecting apparatus of claim 1, wherein the physical effect provided by the assisting and strengthening module is generated by a mechanical mechanism, an electronic mechanism, an optical mechanism, a magnetic mechanism, or a sound mechanism.

3. The optical blood glucose detecting apparatus of claim 1, wherein the chemical effect provided by the assisting and strengthening module is generated by a chemical reaction mechanism, a spreading mechanism, or a spraying mechanism.

4. The optical blood glucose detecting apparatus of claim 1, wherein after the assisting and strengthening module provides the physical effect or the chemical effect on the tissue region to adjust the physical and chemical properties of the tissue region, the data processing module will compare different blood glucose optical reflection messages before and after being assisted and strengthened, or times of assisting and strengthening processes needed to achieve a specific blood glucose concentration to determine a blood glucose concentration.

5. The optical blood glucose detecting apparatus of claim 1, wherein the data processing module comprises:

a blood glucose concentration database, for storing a plurality of default blood glucose concentrations which are assisted and strengthened, the data processing module compares the blood glucose concentration after being assisted and strengthened with the plurality of default blood glucose concentrations in the blood glucose concentration database to determine whether the detected portion is properly selected.

6. A method of operating an optical blood glucose detecting apparatus, the optical blood glucose detecting apparatus comprising a detecting module, an assisting and strengthening module, and a data processing module, the method comprising steps of:

(a) the detecting module providing an incident optical signal to pass through a detected portion of a skin surface into a skin interstitial fluid, and capturing a blood glucose optical reflection message of the skin interstitial fluid, and interfering the blood glucose optical reflection message and the incident optical signal to generate a detected data;

(b) the assisting and strengthening module providing a physical effect or a chemical effect on a tissue region under the detected portion to strengthen the blood glucose optical reflection message; and

(c) the data processing module processing the detected data to determine a blood glucose concentration.

7. The method of claim 6, wherein the physical effect provided by the assisting and strengthening module is generated by a mechanical mechanism, an electronic mechanism, an optical mechanism, a magnetic mechanism, or a sound mechanism.

8. The method of claim 6, wherein the chemical effect provided by the assisting and strengthening module is generated by a chemical reaction mechanism, a spreading mechanism, or a spraying mechanism.

9. The method of claim 6, wherein after the assisting and strengthening module provides the physical effect or the chemical effect on the tissue region to adjust the physical and chemical properties of the tissue region, the data processing module will compare different blood glucose optical reflection messages before and after the being assisted and strengthened, or times of assisting and strengthening processes needed to achieve a specific blood glucose concentration to determine a blood glucose concentration.

10. The method of claim 6, wherein the data processing module comprises a blood glucose concentration database to store a plurality of default blood glucose concentrations which are assisted and strengthened, the data processing module compares the blood glucose concentration after being assisted and strengthened with the plurality of default blood glucose concentrations in the blood glucose concentration database to determine whether the detected portion is properly selected.