TISSUE THICKNESS COMPENSATOR COMPRISING AT LEAST ONE MEDICAMENT

• US 20120241492A1
• Filed: 03/28/2012
• Published: 09/27/2012
• Est. Priority Date: 09/30/2010
• Status: Active Grant

• Current Assignee: Cilag Gmbh International (Johnson & Johnson)
• Original Assignee: Ethicon Endo-Surgery, Inc. (Johnson & Johnson)
• Inventors: Shelton, Frederick E. IV, Schmid, Katherine J., Scheib, Charles J., Aronhalt, Taylor W., Lang, Matthew M., Hall, Steven G., Baxter, Chester O. III
• Granted Patent: US 9,839,420 B2
• Time in Patent Office: Days
• US Class Current: 227/175.1
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/0643 with separate closing member, e.g. for interlocking with staple
• CPC Class Codes: A61B 17/0644 penetrating the tissue, deformable to closed position
• CPC Class Codes: A61B 17/068 Surgical staplers , e.g. containing multiple staples or clampsstaplers containing only one staple A61B17/10; magazines or containers for staples A61B17/105; for performing anastomosis A61B17/115; staplers in general B25C5/00
• CPC Class Codes: A61B 17/072 for applying a row of staples in a single action , e.g. the staples being applied simultaneously
• CPC Class Codes: A61B 17/07207 the staples being applied sequentially
• CPC Class Codes: A61B 17/07292 Reinforcements for staple line, e.g. pledgets
• CPC Class Codes: A61B 17/1155 Circular staplers comprising a plurality of staples
• CPC Class Codes: A61B 17/2909 Handles
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable or resorptive
• CPC Class Codes: A61B 2017/00477 Coupling A61B2017/0046 takes precedence
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/0053 Loading magazines or sutures into applying tools
• CPC Class Codes: A61B 2017/00561 creating a vacuum
• CPC Class Codes: A61B 2017/00818 Treatment of the gastro-intestinal system
• CPC Class Codes: A61B 2017/00862 elastic or resilient
• CPC Class Codes: A61B 2017/00884 enhancing wound closure
• CPC Class Codes: A61B 2017/00889 antimicrobial, disinfectant
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2017/00898 expandable upon contact with fluid
• CPC Class Codes: A61B 2017/00942 : hydrophilic
• CPC Class Codes: A61B 2017/00951 : adhesive
• CPC Class Codes: A61B 2017/07228 : Arrangement of the staples
• CPC Class Codes: A61B 2017/07235 : containing different staples, e.g. staples of different shapes, sizes or materials
• CPC Class Codes: A61B 2017/07242 : achieving different staple heights during the same shot, e.g. using an anvil anvil having different heights or staples of different sizes
• CPC Class Codes: A61B 2017/07264 : characterised by its staple forming cavities, e.g. geometry or material
• CPC Class Codes: A61B 2017/07271 : characterised by its cartridge
• CPC Class Codes: A61B 2017/07278 : characterised by its sled or its staple holder
• CPC Class Codes: A61B 2017/07285 : characterised by its cutter
• CPC Class Codes: A61B 2017/2908 : Multiple segments connected by articulations
• CPC Class Codes: A61B 2017/2919 : details of linkages or pivot points
• CPC Class Codes: A61B 2017/2923 : Toothed members, e.g. rack and pinion
• CPC Class Codes: A61B 2017/2927 : the angular position of the head being adjustable with respect to the shaft
• CPC Class Codes: A61B 2017/2933 : camming or guiding means
• CPC Class Codes: A61B 2017/2936 : Pins in guiding slots
• CPC Class Codes: A61B 2017/2946 : Locking means
• CPC Class Codes: A61B 2017/320052 : Guides for cutting instruments
• CPC Class Codes: A61B 2090/0811 : for the position of a particular part of an instrument with respect to the rest of the instrument, e.g. position of the anvil of a stapling instrument
• CPC Class Codes: A61B 2090/3966 : Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61B 90/92 : coded with colour
• CPC Class Codes: A61L 17/005 : containing a biologically active substance, e.g. a medicament or a biocide
• CPC Class Codes: A61L 2300/102 : Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
• CPC Class Codes: A61L 2300/232 : Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
• CPC Class Codes: A61L 2300/45 : Mixtures of two or more drugs, e.g. synergistic mixtures
• CPC Class Codes: F04C 2270/0421 : Controlled or regulated
• CPC Class Codes: Y10T 29/49826 : Assembling or joining

Abstract

In various embodiments, a tissue thickness compensator can comprise one or more capsules and/or pockets comprising at least one medicament therein. In at least one embodiment, staples can be fired through the tissue thickness compensator to rupture the capsules. In certain embodiments, a firing member, or knife, can be advanced through the tissue thickness compensator to rupture the capsules.

Claims

1. A medicament delivery system attachable to an anvil of a fastening instrument, wherein the anvil includes a forming surface, and wherein said medicament delivery system comprises:

a releasing material comprising a cavity, wherein said cavity is configured to be aligned with the forming surface of the anvil;

a medicament positioned within said cavity; and

an attachment portion configured to be attached to the anvil.

2. The medicament delivery system of claim 1, wherein said cavity is defined by a sidewall, wherein said releasing material comprises a first layer and a second layer, and wherein portions of said first layer are connected to said second layer to define said sidewall.

3. The medicament delivery system of claim 1, wherein said forming surface comprises a forming pocket configured to deform a fastener, and wherein said releasing material is positioned within said forming pocket.

4. The medicament delivery system of claim 1, wherein said medicament can comprise non-woven oxidized regenerated cellulose.

5. The medicament delivery system of claim 1, wherein said cavity comprises a first cavity, and wherein said medicament delivery system further comprises a second cavity and a medicament positioned within said second cavity.

6. The medicament delivery system of claim 5, wherein the forming surface of the anvil comprises a first row of forming pockets configured to deform fasteners and a second row of forming pockets configured to deform fasteners, wherein said first cavity is aligned with said first row of forming pockets, and wherein said second cavity is aligned with said second row of forming pockets.

7. A stapling assembly for use with a stapler, said stapling assembly comprising:

an anvil comprising a plurality of forming surfaces;

a compensator attached to said anvil, wherein said compensator comprises a plurality of cavities aligned with said forming surfaces; and

at least one medicament positioned within each said cavity.

8. The stapling assembly of claim 7, wherein said plurality of forming surfaces comprises an array of forming pockets, wherein each said forming pocket is configured to deform a fastener, and wherein said cavities are aligned with said forming pockets.

9. The stapling assembly of claim 7, wherein said plurality of forming surfaces comprises a first row of forming pockets and a second row of forming pockets, wherein each said forming pocket is configured to deform a fastener, and wherein said plurality of cavities comprises a first cavity aligned with said first row of forming pockets and a second cavity aligned with said second row of forming pockets.

10. The stapling assembly of claim 7, wherein said plurality of cavities comprises a plurality of bubbles.

11. The stapling assembly of claim 10, wherein said plurality of forming surfaces comprises an array of forming pockets, wherein each said forming pocket is configured to deform a fastener, and wherein said bubbles extend into said forming pockets.

12. The stapling assembly of claim 10, wherein said compensator comprises a first layer and a second layer, and wherein said bubbles are defined between said first layer and said second layer.

13. The stapling assembly of claim 7, wherein said at least one medicament comprises powdered oxidized regenerated cellulose.

14. The stapling assembly of claim 7, wherein said at least one medicament comprises a first medicament and a second medicament, and wherein one or more of said cavities includes said first medicament positioned therein and the one or more said cavities includes said second medicament positioned therein.

15. The stapling assembly of claim 7, wherein said at least one medicament comprises a first medicament and a second medicament, and wherein each said cavity comprises said first medicament and said second medicament positioned therein.

16. The stapling assembly of claim 7, wherein said at least one medicament is configured to absorb water and expand.

17. The stapling assembly of claim 7, wherein said at least one medicament comprises hydrogel.

18. A stapling assembly for use with a stapler, said stapling assembly comprising:

an anvil comprising;

a plurality of forming surfaces; and

a slot configured to receive a cutting member;

a compensator attached to said anvil, wherein said compensator comprises a plurality of cavities aligned with said slot; and

at least one medicament positioned within each said cavity.