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MICROSPHERES OF HYDROLYSED STARCH WITH ENDOGENOUS, CHARGED LIGANDS

  • US 20120244198A1
  • Filed: 11/17/2010
  • Published: 09/27/2012
  • Est. Priority Date: 12/04/2009
  • Status: Active Grant
First Claim
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1. A biodegradable microsphere having a diameter of 10-2000 μ

  • m comprising cross-linked hydrolysed starch onto which at least one type of ligand has been coupled via a carboxylic ester bond, wherein said ligand is an endogenous, charged molecule with a molecular mass of less than 1000 Da comprising at least one additional carboxylic acid function and/or at least one amine function, and wherein on average 0.05-1.5 ligands have been coupled to each glucose moiety in the hydrolysed starch.

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