Glucose Monitoring System

• US 20120245445A1
• Filed: 04/14/2011
• Published: 09/27/2012
• Est. Priority Date: 03/21/2011
• Status: Abandoned Application

• Current Assignee: Anita Margarette Chambers, Michael Darryl Black, Trent Huang
• Original Assignee: Anita Margarette Chambers, Michael Darryl Black, Trent Huang
• Inventors: Black, Michael Darryl, Chambers, Anita Margarette, Huang, Trent
• Application Number:
  US13/087,171
• Publication Number:
  US 20120245445A1
• Time in Patent Office: Days
• US Class Current: 600/365
• CPC Class Codes: A61B 10/0045 Devices for taking samples of body liquids devices for taking blood samples A61B5/15
• CPC Class Codes: A61B 17/205 Vaccinating by means of needles or other puncturing devices
• CPC Class Codes: A61B 2010/008 Interstitial fluid
• CPC Class Codes: A61B 5/14514 using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
• CPC Class Codes: A61B 5/1468 using chemical or electrochemical methods, e.g. by polarographic means A61B5/1486 takes precedence
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/15003 for venous or arterial blood
• CPC Class Codes: A61B 5/150167 Adjustable piercing speed of skin piercing element, e.g. blade, needle, lancet or canula, for example with varying spring force or pneumatic drive
• CPC Class Codes: A61B 5/150175 Adjustment of penetration depth
• CPC Class Codes: A61B 5/150282 for piercing elements, e.g. blade, lancet, canula, needle
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150984 Microneedles or microblades
• CPC Class Codes: A61B 5/151 Devices specially adapted for taking samples of capillary blood, e.g. by lancets , needles or blades
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: A61M 2037/0023 Drug applicators using microneedles
• CPC Class Codes: A61M 2037/003 having a lumen
• CPC Class Codes: A61M 2037/0046 Solid microneedles
• CPC Class Codes: A61M 2037/0061 Methods for using microneedles
• CPC Class Codes: A61M 37/0015 by using microneedles
• CPC Class Codes: A61M 5/204 connected to external reservoirs for multiple refilling
• CPC Class Codes: A61M 5/30 : Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
• CPC Class Codes: G16H 40/63 : for local operation

Abstract

A body fluid sampling system for use on a tissue site includes a drive force generator and one or more microneedles operatively coupled to the drive force generator. Each of a microneedle has a height of 500 to 2000 μm and a variable tapering angle of 60 to 90°. A sample chamber is coupled to the one or more microneedles. A body fluid is created when the one or more microneedles pierces a tissue site flows to the sample chamber for glucose detection and analysis.

Claims

1. A body fluid sampling system for use on a tissue site, the system comprising:

a drive force generator;

one or more microneedles operatively coupled to the drive force generator, each of a microneedle having a height of 500 μ

m 50 mm, and a variable tapering angle of 60 to 90°

;

a sample chamber coupled to the one or more microneedles, wherein a body fluid is created when the one or more microneedles pierces a tissue site flows to the sample chamber for glucose detection and analysis.

2. The system of claim 1, wherein each of a microneedle has a height of 3 mm-50 mm.

3. The system of claim 1, wherein each of a microneedle has a height of 5 mm-15 mm.

4. The system of claim 1, wherein each of a microneedle has a height of 500 to 2000 μ

m.

5. The system of claim 1, further comprising:

a position sensor.

6. The system of claim 1, further comprising:

a user interface coupled to a processor.

7. The system of claim 1, further comprising:

a sterility enclosure covering at least a tip of the one or more microneedles.

8. A method of sampling a body fluid at a tissue site, comprising:

providing one or more microneedles, each of a microneedle having a height of 500 μ

m 50 mm, and a variable tapering angle of 60 to 90°

.

introducing the one or more microneedles through a skin surface to a tissue site in a manner to reduce or eliminate pain while creating a flow of body fluid from the tissue site; and

measuring a component in the body fluid.

9. The method of claim 8, wherein the body fluid is blood and the component is glucose.

10. The method of claim 8, wherein the body fluid is introduced to a test strip for measurement of an amount of the component.