APPARATUSES, METHODS, AND COMPOSITIONS FOR THE TREATMENT AND PROPHYLAXIS OF CHRONIC WOUNDS
First Claim
1. A topical composition comprising a lipoic acid derivative and a sacrificial proteolytic enzyme substrate, wherein the lipoic acid derivative and sacrificial proteolytic enzyme substrate form a mixture.
8 Assignments
0 Petitions
Accused Products
Abstract
According to an illustrative embodiment a method to promote healing of a wound is provided comprising contacting the wound with a biologically active composition comprising a lipoic acid derivative and gelatin. In another embodiment a topical composition is provided, which can be formulated as a homogenous mixture, such as a spray, mist, aerosol, lotion, cream, solution, oil, gel, ointment, paste, emulsion or suspension or applied on a carrier material, such as a bandage, gauze, foam, sponge, hydrogel, hydrocolloid, hydrofiber, occlusive dressing, adhesive composition or scaffold. Methods for producing such a topical composition and carrier material with the topical composition applied thereto are also disclosed.
24 Citations
92 Claims
- 1. A topical composition comprising a lipoic acid derivative and a sacrificial proteolytic enzyme substrate, wherein the lipoic acid derivative and sacrificial proteolytic enzyme substrate form a mixture.
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15. A wound dressing for applying treatment to a tissue site comprising:
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a carrier material having a portion to contact the tissue site; and a lipoic acid derivative and a sacrificial proteolytic enzyme substrate applied to the carrier material. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22)
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23-80. -80. (canceled)
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81. A system for treating a wound at a tissue site, comprising:
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a pressure source to supply reduced pressure; wound dressing in fluid communication with said pressure source to distribute reduced pressure to the wound, said wound dressing having a first portion contacting the wound and a second portion; a lipoic acid derivative and a sacrificial proteolytic enzyme applied to the second portion of said wound dressing; and a drape adapted to cover said wound dressing and the wound to provide a sealed space for applying the reduced pressure to the wound. - View Dependent Claims (82, 83, 84, 85, 86, 87, 88, 89, 90, 91)
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92-100. -100. (canceled)
Specification