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ANTI-TOXIN VACCINE COMPOSITIONS AND METHODS OF USE THEREOF

  • US 20120251542A1
  • Filed: 03/05/2012
  • Published: 10/04/2012
  • Est. Priority Date: 03/04/2011
  • Status: Active Grant
First Claim
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1. A ricin ribosome binding mutant that is altered relative to a wild type ricin A chain toxin of SEQ ID NO:

  • 1 at at least two amino acid residues, selected from the group consisting of i) R189A and R234A;

    ii) R193A and R235A;

    iii) R193A and R235A and R189A;

    iv) R193A and R235A and R234A;

    v) R193A and R235A and R189A and R234A; and

    vi) R213A and R258A.

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