METHOD, DEVICE, AND SYSTEM FOR DELIVERY OF THERAPEUTIC AGENTS TO THE EYE

• US 20120253300A1
• Filed: 06/12/2012
• Published: 10/04/2012
• Est. Priority Date: 05/04/2006
• Status: Active Grant

• Current Assignee: ForSight VISION5, Inc. (Abbvie Incorporated)
• Original Assignee: Hek Development, LLC
• Inventors: Kaufman, Herbert Edward
• Granted Patent: US 8,668,920 B2
• Time in Patent Office: Days
• US Class Current: 604/301
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61K 9/0051 Ocular inserts, ocular implants
• CPC Class Codes: A61P 27/02 Ophthalmic agents

Abstract

A method, device, and system for easier, consistent, and comfortable delivery of therapeutic agents to the front of the eye.

Claims

1. A device for delivery of therapeutic agents to the eye, comprising a polymeric structure containing one or more therapeutic agents that conforms to the curvature of a patient'"'"'s outer eye and extends around the circumference of a patient'"'"'s cornea.

5. The device of claim 1, wherein the polymeric structure contains one or more therapeutic agents that are precipitated in the polymer and that will dissolve to allow delivery of the agents into the eye.

7. A system of delivering therapeutic agents to the front of the eye comprising the device of claim 1.

11. A system of delivering therapeutic agents to the front of the eye comprising the device of claim 5.

2. A device for delivery of therapeutic agents to the eye comprising:

a. a polymeric structure that conforms to the curvature of a patient'"'"'s outer eye and extends around the circumference of a patient'"'"'s cornea; and

b. a barrier membrane containing one or more therapeutic agents.

3. The device of claim 2, wherein the barrier membrane runs along the entire bottom surface of the polymeric structure.

4. The device of claim 2, wherein the barrier membrane runs along a portion of the bottom surface of the polymeric structure.

6. The device of claim 2, wherein the polymeric structure contains one or more therapeutic agents that are precipitated in the polymer and that will dissolve to allow delivery of the agents into the eye.

8. A system of delivering therapeutic agents to the front of the eye comprising the device of claim 2.

9. A system of delivering therapeutic agents to the front of the eye comprising the device of claim 3.

10. A system of delivering therapeutic agents to the front of the eye comprising the device of claim 4.

12. A system of delivering therapeutic agents to the front of the eye comprising the device of claim 6.