METHODS, SOFTWARE ARRANGEMENTS, STORAGE MEDIA, AND SYSTEMS FOR PROVIDING A SHRINKAGE-BASED SIMILARITY METRIC
First Claim
1. A method for determining an association between a first dataset and a second dataset comprising:
- a) obtaining at least one first data corresponding to one or more prior assumptions regarding said first and second datasets;
b) obtaining at least one second data corresponding to one or more portions of actual information regarding said first and second datasets; and
c) using a hardware processing arrangement, combining the at least one first data and the at least one second data to determine the association between the first and second datasets.
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention relates to systems, methods, and software arrangements for determining associations between two or more datasets. The systems, methods, and software arrangements used to determine such associations include a determination of a correlation coefficient that incorporates both prior assumptions regarding such datasets and actual information regarding the datasets. The systems, methods, and software arrangements of the present invention can be useful in an analysis of microarray data, including gene expression arrays, to determine correlations between genotypes and phenotypes. Accordingly, the systems, methods, and software arrangements of the present invention may be utilized to determine a genetic basis of complex genetic disorder (e.g. those characterized by the involvement of more than one gene).
5 Citations
74 Claims
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1. A method for determining an association between a first dataset and a second dataset comprising:
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a) obtaining at least one first data corresponding to one or more prior assumptions regarding said first and second datasets; b) obtaining at least one second data corresponding to one or more portions of actual information regarding said first and second datasets; and c) using a hardware processing arrangement, combining the at least one first data and the at least one second data to determine the association between the first and second datasets.
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2-24. -24. (canceled)
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25. A non-transitory computer-readable medium for determining an association between a first dataset and a second dataset, including instructions thereon that are accessible by a hardware processing arrangement, wherein, when the processing, arrangement executes the instructions, the processing arrangement is configured to perform procedures comprising:
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a) obtaining at least one first data corresponding to one or more prior assumptions regarding said first and second datasets; b) obtaining at least one second data corresponding to one or more portions of actual information regarding said first and second datasets; and c) combining the at least one first data and the at least one second data to determine the association between the first and second datasets. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48)
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49-72. -72. (canceled)
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73. A system for determining an association between a first dataset and a second dataset comprising a hardware processing arrangement configured to perform procedures comprising:
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a) obtaining at least one first data corresponding to one or more prior assumptions regarding said first and second datasets; b) obtaining at least one second data corresponding to one or more portions of actual information regarding said first and second datasets; and c) with, the processing arrangement, combining the at least one first data and the at least one second data to determine the association between the first and second datasets.
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74-96. -96. (canceled)
Specification