TREATMENT OF POSTPRANDIAL HYPERGLYCEMIA BY GASTRIC ELECTRICAL STIMULATION
First Claim
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1. A method of treating hyperglycemia in a patient comprising:
- measuring a blood glucose level of the patient;
determining whether the blood glucose level exceeds a predetermined threshold and if the blood glucose level exceeds the predetermined threshold,delivering gastric electrical stimulation (GES) to a gastrointestinal tract (GI) of the patient.
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Abstract
In some examples, the disclosure relates to a systems, devices, and techniques for delivering electrical stimulation therapy to a patient. In some example, the disclosure relates to systems and methods of treating hyperglycemia in a patient including delivering gastric electrical stimulation (GES) to the patient. Devices, systems and methods according to the disclosure may comprise an implantable stimulator, a blood glucose monitor and/or a food intake sensor. In some examples, a blood glucose level and/or food intake of a patient is detected and GES is delivered to the patient in response to the detection.
46 Citations
31 Claims
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1. A method of treating hyperglycemia in a patient comprising:
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measuring a blood glucose level of the patient; determining whether the blood glucose level exceeds a predetermined threshold and if the blood glucose level exceeds the predetermined threshold, delivering gastric electrical stimulation (GES) to a gastrointestinal tract (GI) of the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method of treating postprandial hyperglycemia of a patient comprising:
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detecting the onset of consumption of food by the patient; delivering gastric electrical stimulation (GES) to the patient in response to the detection; wherein detecting the onset of consumption of food comprises detecting an event from the group consisting of;
contractile activity of the stomach, a change in the time of day, a change in a volume of the stomach, and a change in an electrical impedance between at least two electrodes located adjacent the stomach. - View Dependent Claims (16, 17, 18, 19)
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20. A method of treating postprandial hyperglycemia of a patient comprising:
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measuring a stomach content of the patient comprising detecting the presence of food in the stomach of the patient; delivering gastric electrical stimulation (GES) to the patient in response to the detection; and turning on a stimulation timer. - View Dependent Claims (21, 22)
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23. A method of managing a blood glucose level of a patient comprising:
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delivering gastric electrical stimulation (GES) to a gastrointestinal tract (GI) of the patient; wherein the GES comprises a signal comprising an alternating monophasic waveform.
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24. A system for managing a blood glucose level of a patient comprising:
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a blood glucose monitor configured to measure the blood glucose level; an implantable stimulator configured to deliver gastric electrical stimulation (GES) to a gastrointestinal tract (GI) of the patient; wherein the implantable stimulator is configured to generate and deliver the GES when the blood glucose level exceeds a predetermined threshold. - View Dependent Claims (25, 26, 27, 28, 29, 30)
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31. A system for managing a blood glucose level of a patient comprising:
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a food intake sensor; an implantable stimulator configured to deliver gastric electrical stimulation (GES) to a gastrointestinal tract (GI) of the patient; wherein the implantable stimulator is configured to generate and deliver the GES when the food intake sensor senses ingestion of food by the patient.
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Specification