SYSTEM FOR PERFORMING REMOTE ISCHEMIC CONDITIONING

• US 20120265240A1
• Filed: 04/15/2011
• Published: 10/18/2012
• Est. Priority Date: 04/15/2011
• Status: Active Grant

• Current Assignee: CellAegis Devices, Inc.
• Original Assignee: CellAegis Devices, Inc.
• Inventors: Gil, Lahav, Gadzic, Rade, Caldarone, Christopher, Redington, Andrew, Ganske, Rocky, Shepperdley, Adam, Cracauer, Raymond, Royblat, Igal, Christensen, Kristopher Thomas
• Granted Patent: US 8,764,789 B2
• Time in Patent Office: Days
• US Class Current: 606/202
• CPC Class Codes: A61B 17/1325 with means for applying local pressure pressure pads A61F5/30
• CPC Class Codes: A61B 17/1355 Automated control means therefor
• CPC Class Codes: A61B 2017/00123 and automatic shutdown
• CPC Class Codes: A61B 2017/00477 Coupling A61B2017/0046 takes precedence
• CPC Class Codes: A61B 2017/00858 high friction, non-slip on handles A61B2017/00429
• CPC Class Codes: A61B 2090/065 for measuring contact or contact pressure
• CPC Class Codes: A61B 5/02233 Occluders specially adapted therefor tourniquets A61B17/132
• CPC Class Codes: A61H 2201/0107 modular
• CPC Class Codes: A61H 2201/0176 By stopping operation
• CPC Class Codes: A61H 2201/0184 by raising an alarm
• CPC Class Codes: A61H 2201/165 Wearable interfaces
• CPC Class Codes: A61H 2201/501 connected to external computer devices or networks
• CPC Class Codes: A61H 2201/5035 Several programs selectable
• CPC Class Codes: A61H 2201/5038 freely programmable by the user
• CPC Class Codes: A61H 2201/5041 control is restricted to certain individuals
• CPC Class Codes: A61H 2201/5043 Displays
• CPC Class Codes: A61H 2201/5071 Pressure sensors
• CPC Class Codes: A61H 2201/5097 wireless
• CPC Class Codes: A61H 2230/305 used as a control parameter for the apparatus A61H2230/045 takes precedence
• CPC Class Codes: A61H 9/0078 with intermittent or alternately inflated bladders or cuffs mattresses for preventing bed-sores with alternated pressurized chambers A61G7/05776
• CPC Class Codes: A61H 9/0092 : Cuffs therefor

Abstract

A system for performing remote ischemic conditioning includes an inflatable cuff configured to encircle a limb of a subject and a controller removably attached to the cuff. The controller includes a pump; a manifold in fluid communication with the pump; a connector in fluid communication with the manifold and in removable fluid communication with the inflatable cuff; a pressure sensor; and a control circuit configured to implement a remote ischemic conditioning treatment protocol.

Claims

1. A device for remote ischemic conditioning comprising:

an inflatable cuff configured to encircle a limb of a subject;

a controller removably attached to the cuff, wherein the controller comprises;

a pump;

a manifold in fluid communication with the pump;

an outlet in fluid communication with the manifold and in removable fluid communication with the inflatable cuff;

a pressure sensor; and

a control circuit configured to implement a remote ischemic conditioning treatment protocol.

2. The device of claim 1, wherein the controller further comprises at least one valve configured to open in response to an over pressure event.

3. The device of claim 1, wherein the control circuit maintains a cuff pressure between preselected pressure limits during an ischemic duration of the remote ischemic conditioning treatment protocol.

4. The device of claim 3, wherein the preselected pressure limits are 200 and 210 mmHg.

5. The device of claim 1, wherein the controller is removably attached to the cuff by selective attachment to a controller attachment section disposed on the cuff.

6. A cuff assembly for encircling a limb of a subject comprising:

an inner layer;

an outer layer comprising two flexible foam sections spaced apart in a longitudinal direction of the cuff assembly and an intermediate section disposed between the two flexible foam sections having a greater rigidity than the two flexible foam sections; and

a bladder disposed between the inner cloth layer and the outer layer.

7. The cuff assembly of claim 6, wherein the intermediate section includes a curved inner surface extending in a longitudinal direction of the cuff assembly.

8. The cuff assembly of claim 6, wherein the two flexible foam sections include a plurality of reinforcing structures substantially aligned in an axial direction of the cuff assembly.

9. The cuff assembly of claim 6 further comprising at least one non-slip structure disposed on an exterior face of the inner layer.

10. The cuff assembly of claim 9, wherein the non-slip structure comprises a strip of silicone.

11. The cuff assembly of claim 6 wherein the inner layer comprises a cloth.

12. The cuff assembly of claim 11 wherein the cloth comprises a felt.

13. The cuff assembly of claim 6, wherein a fluid inlet to the bladder extends from the bladder through the intermediate section of the outer layer.

14. The cuff assembly of claim 6 further comprising a fastener.

15. The cuff assembly of claim 14 wherein the fastener comprises a hook and loop fastener.

16. A device comprising;

an inflatable cuff configured to encircle a limb of a subject, wherein an axial direction of the cuff is substantially parallel to an axis of the limb when the cuff is in the fitted state; and

a controller attachment section operatively attached to the cuff by at least one attachment joint oriented substantially parallel to the axial direction of the cuff, wherein the controller attachment section includes a connector adapted for removable attachment of a controller, wherein the controller attachment section provides fluid communication between the controller and cuff in a location removed from the connector when the controller is in an attached state.

17. The device of claim 16, wherein the at least one joint comprises at least two joints oriented substantially parallel to the axial direction of the cuff and spaced apart in a longitudinal direction of the cuff.

18. The device of claim 16, wherein a bottom surface of the controller attachment section substantially conforms to an outer surface of the cuff.

19. The device of claim 16, wherein the at least one joint comprises a sewn seam, an ultrasonic weld, an adhesive, and/or rivets.

20. The device of claim 16, wherein the connector comprises a retaining tab located along a periphery of the controller attachment section.

21. The device of claim 16, wherein fluid communication to the bladder is provided through the controller attachment section.

22. The device of claim 16, wherein the controller attachment section further comprises a conduit that seats in an appropriately configured and sealed receptacle of the inflatable cuff.