SKIN SURFACE ELECTRODES

• US 20120271141A1
• Filed: 10/18/2010
• Published: 10/25/2012
• Est. Priority Date: 10/21/2009
• Status: Abandoned Application

• Current Assignee: Epi-Sci, LLC
• Original Assignee: Epi-Sci, LLC
• Inventors: Davies, Richard J., Davies, Mary K.
• Application Number:
  US13/502,439
• Publication Number:
  US 20120271141A1
• Time in Patent Office: Days
• US Class Current: 600/382
• CPC Class Codes: A61B 2562/0215 Silver or silver chloride containing
• CPC Class Codes: A61B 2562/0217 Electrolyte containing
• CPC Class Codes: A61B 2562/043 in a linear array
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/4312 Breast evaluation or disorder diagnosis A61B5/0091 takes precedence
• CPC Class Codes: A61B 5/6834 using vacuum

Abstract

An apparatus (10) adapted to contact epithelial tissue, the apparatus comprising a cup (12) having a concave shape and adapted to be positioned on epithelial tissue, the cup capable of maintaining a reduced air pressure and holding a volume of flowable material; and an electrical support structure (14) comprising a support structure and a plurality of sensors, electrodes, or both (15) configured to interact with epithelial and subepithelial tissue.

Claims

1. An apparatus for determining electrophysiological characteristics of subepithelial tissue, the apparatus comprising a cup adapted to contact epithelial tissue, the cup comprising a surface having a concave shape, having a volume enclosed by the cup and the epithelial tissue, the cup capable of maintaining a reduced air pressure and holding a volume of flowable material;

and an electrical support structure comprising a connection between an instrument for measuring or recording electrical signals and a plurality of sensors, electrodes or both configured to interact with the epithelial and subepithelial tissue.

2. The apparatus of claim 1, wherein the cup further comprises at least one port.

3. The apparatus of claim 2, wherein the cup further comprises a reservoir, comprising a volume of the flowable material, in connection with a first port through which at least a portion of the flowable material may be transferred to the volume of the cup.

4. The apparatus of claim 3, further comprising a pump in connection with the reservoir to transfer the at least a portion of the flowable material to the volume of the cup.

5. The apparatus of claim 3, wherein the cup further comprises an overflow reservoir.

6. The apparatus of claim 5, wherein the cup further comprises a valve positioned on a path between the cup and the overflow reservoir for facilitating, maintaining or both, a reduced air pressure within the volume of the cup.

7. The apparatus of claim 3 further comprising at least a second port, wherein the second port is positioned between the cup and the valve.

8. The apparatus of claim 1, wherein one or more flowable materials having identified chemical, electrical or physiological properties are used to effect electrophysiological changes in the subepithelial tissue.

9. The apparatus of claim 1, wherein the flowable material is a chemical agent, capable of effecting a physiological response in the subepithelial tissue, the chemical agent including a defined ionic concentration, a pharmacological agent, a hormone, or any combination thereof.

10. The apparatus of claim 8, wherein at least two flowable materials are used in series.

11. The apparatus of claim 1, further comprising a puncture seal comprising a portion of the surface of the cup.

12. The apparatus of claim 1, wherein at least one electrical condition or property is impressed on the electrodes or sensors in order to effect electrophysiological changes in the subepithelial tissue including altering the voltage type or level, current type or level, location of sensors, or any combination thereof.

13. The apparatus of claim 1, wherein the cup is deformable upon the generation of the reduced air pressure or upon application of pressure to an outer surface of the concave shape.

14. The apparatus of claim 1, wherein at least one of the plurality of sensors, electrodes or both is positioned within the volume enclosed by the cup and the epithelial tissue.

15. The apparatus of claim 1, wherein the electrical support structure is configured to have a shape of a central hub with multiple radial arms extending therefrom, an annulus or a circular or ellipsoid disk.

16. The apparatus of claim 15, wherein the plurality of sensors, electrodes or both are positioned on the electrical support structure substantially throughout the shape of the electrical support structure.

17. The apparatus of claim 1, wherein at least one of the plurality of sensors, electrodes or both comprises a spiked electrode.

18. An apparatus for detecting electrophysiological characteristics in breast tissue, including nipple ducts and subepithelial tissue, the apparatus comprising a cup having a concave shape and adapted to be positioned over an area immediately surrounding a nipple of the breast, the cup capable of maintaining a reduced air pressure and holding a volume of flowable material within a volume defined by the concave shape of the cup and an area immediately surrounding the nipple;

a reservoir, integral with the cup, comprising a volume of flowable material, the reservoir adapted to connect with the volume of the cup through a port through which at least a portion of the volume of flowable material may be transferred to the volume of the cup;

an instrument for measuring or recording electrical signals; and

a plurality of electrodes, sensors, or both attachably configured in, on, or adjacent to the cup, adapted to interact with the nipple, ductal and epithelial tissue of the breast.

19. The apparatus of claim 18, further comprising a pump in connection with the reservoir to transfer the at least a portion of the flowable material to the volume of the cup.

20. The apparatus of claim 19, wherein the cup further comprises an overflow reservoir.

21-32. -32. (canceled)