Assembly and Indicator for a Drug Delivery Device

• US 20120271243A1
• Filed: 09/21/2010
• Published: 10/25/2012
• Est. Priority Date: 09/23/2009
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Plumptre, David, Veasey, Robert, Jones, Matthew, Terry, Warren, Claughton, Timothy Giles
• Granted Patent: US 9,511,193 B2
• Time in Patent Office: Days
• US Class Current: 604/189
• CPC Class Codes: A61M 2005/3125 specific display means, e.g. to indicate dose setting
• CPC Class Codes: A61M 2205/584 having a color code
• CPC Class Codes: A61M 5/3146 Priming, e.g. purging, reducing backlash or clearance
• CPC Class Codes: A61M 5/31555 by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button
• CPC Class Codes: A61M 5/31593 Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir

Abstract

An assembly for a drug delivery device (1), comprising a housing (2) having a proximal end and a distal end, a piston rod (8) and an indicator (13). The piston rod (8) is adapted to be displaced distally with respect to the housing (2) away from a proximal start position and towards a distal end position for delivering a drug (31). The indicator (13) is adapted for indicating at least two different operation conditions of the assembly, the indicator (13) being moveable with respect to the housing (2) from a first indication position for a first condition of the assembly into a second indication position for a second condition of the assembly. The piston rod (8) and the indicator (13) are configured to mechanically interact for converting movement of the piston rod (8) into movement of the indicator (13). A first detent (21) is provided which is configured to releasably secure the indicator (13) in the first indication position such that movement into the second indication position is allowed. A second detent (22) is provided which is configured to secure the indicator (13) in the second indication position such that movement into the first indication position is prevented.

Claims

1. An assembly for a drug delivery device, comprising:

a housing having a proximal end and a distal end,

a piston rod which is adapted to be displaced distally with respect to the housing away from a proximal start position and towards a distal end position for delivering a drug,

an indicator for indicating at least two different operation conditions of the assembly, the indicator being moveable with respect to the housing from a first indication position for a first condition of the assembly into a second indication position for a second condition of the assembly, wherein

the piston rod and the indicator are configured to mechanically interact for converting movement of the piston rod into movement of the indicator, and wherein

a first detent is provided which is configured to releasably secure the indicator in the first indication position such that movement into the second indication position is allowed, and

a second detent is provided which is configured to secure the indicator in the second indication position such that movement into the first indication position is prevented.

2. The assembly according to claim 1, wherein the second detent irreleasably secures the indicator in the second indication position while the piston rod travels to the distal end position.

3. The assembly according to claim 1, wherein the piston rod is rotatable in a first rotational direction with respect to the housing and, wherein, the indicator is arranged and configured to mechanically interact with the piston rod such that the indicator is at least partly rotated together with the piston rod in the first rotational direction when the assembly switches from the first indication position into the second indication position.

4. The assembly according to claim 3, wherein the first detent comprises a ramp for releasably securing the indicator in the first indication position, and, wherein, the ramp rises in the first rotational direction.

5. The assembly according to claim 1, wherein the indicator comprises the first detent and the second detent.

6. The assembly according to claim 1, comprising a drive member and a dose button, wherein the dose button is moveable with respect to the housing, with movement of the dose button being converted into movement of the drive member by mechanical interaction of dose button and drive member, wherein movement of the dose button in the distal direction with respect to the housing causes transition of the indicator from the first indication position into the second indication position.

7. The assembly according to claim 6, comprising at least one counter element for engaging the respective detent, wherein the at least one counter element is part of the drive member and, wherein, when the counter element engages with one of the detents, the counter element is disengaged from the other one of the detents.

8. The assembly according to claim 1, wherein the indicator comprises an inner member and an outer indication element, the inner member and the outer indication element being resiliently connected with each other such that the outer indication element is moveable with respect to the inner member when switching from the first indication position into the second indication position.

9. The assembly of claim 8, wherein the inner member is configured to cooperate with the piston rod for switching from the first indication position into the second indication position and, wherein, the inner member comprises at least one first interaction surface, wherein movement of the piston rod is converted into movement of the indicator by mechanical cooperation of the first interaction surface and the piston rod.

10. The assembly of claim 8, wherein the inner member comprises at least one second interaction surface, with mechanical cooperation of the second interaction surface and the piston rod keeping the indicator in the first indication position.

11. The assembly of claim 10, wherein the first interaction surface protrudes radially outwardly from the inner member and the second interaction surface is arranged closer to a proximal end of the piston rod than the first interaction surface, and, wherein an angular distance between the second interaction surface and the piston rod is smaller than an angular distance between the first interaction surface and the piston rod.

12. The assembly according to claim 8, wherein the inner member and the outer indication element are connected by means of at least one flexible member and, wherein, when the first detent and the second detent are disengaged from the counter element, the flexible member provides a force which tends to displace the indicator element in the distal direction with respect to the housing.

13. The assembly according to claim 12, wherein the flexible member is secured to an end face of the outer indication element, the flexible member running in the radial direction with respect to the housing and, wherein the flexible member is shaped s-like.

14. The assembly according to claim 12, wherein the dose button comprises a plurality of protrusions arranged on an inner surface of the dose button, the protrusions being configured to mechanically interact with the at least one flexible member such that movement of the indicator away from the second indication position and back towards the first indication position is prevented.

15. The assembly according to claim 1, wherein the indicator is configured to be a prime status indicator and, wherein, the first indication position denotes an unprimed condition of the assembly and, wherein the second indication position denotes a primed condition of the assembly.

16. An indicator for a drug delivery device, the indicator comprising an inner member and an outer indication element, the outer indication element providing an indication surface and being resiliently connected to the inner member by at least one flexible member, wherein the indicator comprises at least one first detent and at least one second detent, the first detent being adapted to enable rotation of the indicator in a first direction and the second detent being adapted to prevent rotation of the indicator in the direction opposite to the first direction.