PLASMA OR SERUM PRODUCTION AND REMOVAL OF FLUIDS UNDER REDUCED PRESSURE
First Claim
1. A device for receiving bodily fluid from a subject and processing the bodily fluid to form plasma or serum, the device comprising:
- an opening for introduction of a bodily fluid from the subject into the device;
a separation membrane in fluid communication with the inlet on a first side of the membrane;
a vacuum chamber having a pressure less than ambient pressure; and
a seal that can be manipulated to control a fluid communication pathway between the vacuum chamber and a second side of the separation membrane.
6 Assignments
0 Petitions
Accused Products
Abstract
In some embodiments, the present invention generally relates to the separation of blood within a device to form plasma or serum. In some embodiments, the present invention generally relates to the removal of fluids, such as blood, contained within a device. For example, a device may be applied to the skin of a subject to receive blood from the subject and pass the blood through a separation membrane, which separates the blood into plasma and a portion concentrated in blood cells. As another example, blood or plasma may be allowed to clot within the device and serum (the unclotted portion of the blood) may be withdrawn from the device. The device may contain, in some cases, a vacuum source such as a pre-packaged vacuum to facilitate receiving of blood and/or passage of the blood through the separation membrane to produce plasma or serum.
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Citations
121 Claims
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1. A device for receiving bodily fluid from a subject and processing the bodily fluid to form plasma or serum, the device comprising:
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an opening for introduction of a bodily fluid from the subject into the device; a separation membrane in fluid communication with the inlet on a first side of the membrane; a vacuum chamber having a pressure less than ambient pressure; and a seal that can be manipulated to control a fluid communication pathway between the vacuum chamber and a second side of the separation membrane. - View Dependent Claims (9, 10, 15, 16, 18, 20, 28, 35, 42, 60, 61, 62, 64, 65, 67)
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2-8. -8. (canceled)
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11-14. -14. (canceled)
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17. (canceled)
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19. (canceled)
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21-27. -27. (canceled)
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29-34. -34. (canceled)
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36-41. -41. (canceled)
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43-59. -59. (canceled)
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63. (canceled)
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66. (canceled)
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68-74. -74. (canceled)
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75. A device for receiving bodily fluid from a subject, the device comprising:
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an inlet for introduction of a bodily fluid from the subject into the device; a storage chamber; a first membrane that is substantially impermeable to cells, wherein the first membrane separates the inlet from the storage chamber; a second membrane that is gas permeable but is substantially liquid impermeable; a vacuum chamber having a pressure less than ambient pressure; and a seal that can be manipulated to control a fluid communication pathway between the vacuum chamber and the storage chamber. - View Dependent Claims (76)
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77-116. -116. (canceled)
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117. A device for receiving bodily fluid from a subject, the device comprising:
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an inlet for introduction of a bodily fluid from the subject into the device; a storage chamber; a first membrane that is substantially impermeable to cells, wherein the first membrane separates the inlet from the storage chamber; a vacuum chamber having a pressure less than ambient pressure; and a second membrane that is gas permeable but is substantially liquid impermeable, wherein the second membrane separates the storage chamber from the vacuum chamber.
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118-119. -119. (canceled)
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120. A method of producing plasma or serum from blood, the method comprising:
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applying a device to the skin of a subject; and causing the device to receive no more than about 10 ml of blood from the subject, wherein the blood received from the subject is separated within the device to form plasma or serum.
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121-177. -177. (canceled)
Specification