Therapeutic Treatment of Dermatologic Skin Disorders

• US 20120276189A1
• Filed: 10/23/2007
• Published: 11/01/2012
• Est. Priority Date: 10/23/2007
• Status: Abandoned Application

• Current Assignee: Benjamin Johnson
• Original Assignee: Benjamin Johnson
• Inventors: Johnson, Benjamin
• Application Number:
  US11/877,614
• Publication Number:
  US 20120276189A1
• Time in Patent Office: Days
• US Class Current: 424/450
• CPC Class Codes: A61K 31/716 Glucans
• CPC Class Codes: A61K 8/14 Liposomes; Vesicles
• CPC Class Codes: A61K 8/73 Polysaccharides
• CPC Class Codes: A61K 9/0014 Skin, i.e. galenical aspects of topical compositions non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00
• CPC Class Codes: A61K 9/127 Liposomes
• CPC Class Codes: A61P 17/02 for treating wounds, ulcers, burns, scars, keloids, or the like
• CPC Class Codes: A61P 35/00 Antineoplastic agents
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations

Abstract

β-glucans are incorporated with liposomes in therapeutic compositions for topical application to prevent or alleviate the conditions and symptoms of cosmetic and dermatologic disorders. In particular, β-glucan is combined with liposomes to increase the penetration of the β-glucan into the skin, to provide hydration of the skin during treatment. The deeper penetration of the β-glucan increases macrophage activity to remove scar tissue, dead skin cells and other foreign debris as well as stimulating collagen growth to improve skin health.

Claims

1. A method for increasing the transdermal penetration of β

-glucans compounds from a topical skin care application, said method comprising the steps of;

providing a β

-glucan compound in the skin care application; and

providing said β

-glucan compound within a liposome compound to increase the transdermal penetration of said β

-glucan compound.

2. The method for increasing the transdermal penetration providing β

-glucan from a topical skin care application of claim 1 wherein step of providing said β

-glucan compound includes;

providing β

-glucan having linkages at 1 and 3.

3. The method for increasing the transdermal penetration of β

-glucan from a topical skin care application of claim 1 wherein step of providing said β

-glucan compound includes;

providing β

-glucan having linkages at 1 and 3 and side linkages at 1 and 6.

4. The method for increasing the transdermal penetration of β

-glucan from a topical skin care application of claim 1 wherein step of providing said β

-glucan compound includes;

providing said β

-glucan compound in the range of between 0.1 percent to 20 percent by weight.

5. The method for increasing the transdermal penetration of β

-glucan from a topical skin care application of claim 1 wherein step of providing said β

-glucan compound includes;

providing lipid compounds having enhanced penetration properties.

6. The method for increasing the transdermal penetration of β

-glucan from a topical skin care application of claim 1 wherein step of providing said β

-glucan compound includes;

providing said liposome compound in the range of 0.1 percent to 20 percent by weight.

7. The method for increasing the transdermal penetration of β

-glucan from a topical skin care application of claim 1 wherein step of providing said β

-glucan compound includes;

providing a lipid compound having a high affinity for water.

8. A topical composition for therapeutic treatment of skin, said composition comprising:

a liposomal compound; and

a β

-glucan compound contained within said liposomal compound.

9. The topical composition of claim 8 wherein said β

-glucan compound includes;

β

-glucan having linkages at 1 and 3.

10. The topical composition of claim 8 wherein said β

-glucan compound includes;

β

-glucan having linkages at 1 and 3 and side linkages at 1 and 6.

11. The topical composition of claim 8 wherein said composition includes:

β

-glucan compound in a range of between 0.1 and 20 percent by weight.

12. The topical composition of claim 8 wherein said composition includes:

said liposomal compound has a high affinity for water.

13. A method for removing scar tissue from damaged skin, said method comprising:

providing a liposomal compound;

providing a β

-glucan compound contained within said liposomal compound;

applying said β

-glucan compound contained within said liposomal compound to the damaged skin.

14. The method for removing scar tissue from damaged skin of claim 13 wherein step of providing said β

-glucan compound includes;

providing β

-glucan having linkages at 1 and 3.

15. The method for removing scar tissue from damaged skin of claim 13 wherein step of providing said β

-glucan compound includes;

providing β

-glucan having linkages at 1 and 3 and side linkages at 1 and 6.

16. The method for removing scar tissue from damaged skin of claim 13 wherein step of providing said β

-glucan compound includes;

providing said β

-glucan compound in the range of between 0.1 percent to 20 percent by weight.

17. A method for treating basal cell carcinoma, said method comprising:

providing a liposomal compound;

providing a β

-glucan compound contained within said liposomal compound;

applying said β

-glucan compound contained within said liposomal compound to the basal cell carcinoma in the skin.

18. The method for treating basal cell carcinoma of claim 17 wherein step of providing said β

-glucan compound includes;

providing β

-glucan having linkages at 1 and 3.

19. The method for treating basal cell carcinoma of claim 17 wherein step of providing said β

-glucan compound includes;

providing β

-glucan having linkages at 1 and 3 and side linkages at 1 and 6.

20. The method for treating basal cell carcinoma of claim 17 wherein step of providing said β

-glucan compound includes;

providing said β

-glucan compound in the range of between 0.1 percent to 20 percent by weight.