THERAPEUTIC AGENT DELIVERY APPARATUS AND PROCESS

• US 20120283186A1
• Filed: 12/03/2010
• Published: 11/08/2012
• Est. Priority Date: 12/30/2009
• Status: Active Grant

• Current Assignee: Dr. Kenneth Adams Medicine Professional Corporation
• Original Assignee: Adams Patent Corporation
• Inventors: Adams, Kenneth W.
• Granted Patent: US 10,709,882 B2
• Time in Patent Office: Days
• US Class Current: 514/8.6
• CPC Class Codes: A61M 37/00 Other apparatus for introducing media into the body for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30; Percutany, i.e. introducing medicines into the body by diffusion through the skin salt baths A61H33/04
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/178 Syringes
• CPC Class Codes: A61M 5/31 Details

Abstract

A method and device to deliver medication in a liquid, gel or suspension formulation to a plurality of adjacent tissue sites of a mammal, the device comprising a plurality of tissue-engaging members for receiving the medication and operably engageable with the plurality of tissue sites; means for supplying the tissue-engaging members with the formulation, and to temporarily sustain and control the rate of therapeutic agent/unit of time and preferably to sustain these controlled delivery rates over extended periods of time to enhance the local therapeutic effect of these therapeutic agents and to reduce the systemic toxicity and reduce unwanted side effects.

Claims

1. A device to deliver medication in a liquid formulation to a plurality of adjacent tissue sites of a mammal, said device comprising:

a plurality of tissue-engaging members for receiving said medication and operably engageable with said plurality of tissue sites; and

means for supplying said tissue-engaging members with said formulation.

2. A device as claimed in claim 1 wherein each of said tissue-engageable members comprises a syringe needle for injecting.

3. A device as claimed in claim 1 wherein each of said tissue-engageable members comprise a formulation absorbent material for topical application of said medication.

4. A device as claimed in claim 1 comprising a plurality of medication reservoirs in communication with said tissue-engaging members.

5. A device as claimed in claim 1 comprising a common medication reservoir in communication with at least two of said tissue engaging members.

6. A device as claimed in claim 1 wherein said means for supplying said tissue-engaging members with said formulation comprises activatable plunger means to one or multiple syringes.

7. A device as claimed in claim 1 wherein said means for supplying said tissue-engaging members with said formulation comprises a single pump/plunger with a controllable mechanical device to sequentially open gates to the plurality of tissue engaging member to individually control the medication dose per unit time to each individual or grouping of sites.

8. A device as claimed in claim 1 wherein said means for supplying said tissue-engaging members with said formulation comprises a multitude of individual pumps each supplying an individually controlled or globally controlled rate of therapeutic agent delivered to a plurality of tissues sites.

9. A method of administering a medicament to a plurality of distinct sites of tissue, lesion or organ comprising:

selecting said sites; and

administering said medicament to each of said sites.

10. A method as claimed in claim 9 comprising administering said medicament in a manner selected from simultaneously, synchronously, individually in a routine or selected sequence at selected volumes and rates.

11. A method as claimed in claim 9 comprising injecting said medicament at said plurality of sites.

12. A method as claimed in claim 9 comprising effecting a scan of said tissue, lesion or organ selected from MRI, CAT, CT and ultrasound;

reviewing selected desired sites from said scan; and

administering said medicament to selected distinct depths at said selected sites.

13. A method as claimed in claim 9 comprising feeding said medicament to a plurality of suitably located adjacent syringes or catheters.

14. A method as claimed in claim 13 comprising dispensing said medicaments to said sites simultaneously, synchronously, individually in a routine or selected sequence at selected volumes and rates.

15. A method as claimed in claim 9 comprising topically administering said medicament to said sites.