APPARATUS AND METHOD FOR ELECTROCARDIOGRAM-ASSISTED BLOOD PRESSURE MEASUREMENT
First Claim
1. A sensing unit, comprisinga. a cuff for measuring blood pressure, comprising a first dry flexible sensing electrode positioned between a human body part and an inside surface of the cuff, for connection to a human body;
- b. one or more dry flexible ground electrodes positioned between a human body part and an inside surface of the cuff for connection to the human body; and
c. a second sensing dry electrode for connection to the human body such that a heart of the human body is intermediate the first sensing and second sensing electrodes.
0 Assignments
0 Petitions
Accused Products
Abstract
Apparatus, method, and software for electrocardiogram-assisted non-invasive arterial blood pressure d stiffness measurement is disclosed including brachial cuff with flexible electrodes, control box with rigid electrodes, and associated hardware/software. Cuff is wrapped around upper arm while electrodes on device are touched with fingers of other hand. Device acquires simultaneous ECG/oscillometric data during cuff deflation. Processing unit determines ECG R-peak positions to isolate arterial pulses and calculate pulse transit time. Change in pulse amplitude as function of cuff pressure is used for constructing oscillometric envelope and calculating blood pressure using empirical coefficients. Change in pulse transit time as function of cuff pressure is used independently for constructing pulse transit time envelopes and finding blood pressure with/without empirical coefficients. Fusion algorithm combines results for robust blood pressure and vessel stiffness evaluation. Device sends physiological information to personal computer/smartphone wirelessly, for further analysis. Computer/smartphone transmits information to third party for patient management.
26 Citations
19 Claims
-
1. A sensing unit, comprising
a. a cuff for measuring blood pressure, comprising a first dry flexible sensing electrode positioned between a human body part and an inside surface of the cuff, for connection to a human body; -
b. one or more dry flexible ground electrodes positioned between a human body part and an inside surface of the cuff for connection to the human body; and c. a second sensing dry electrode for connection to the human body such that a heart of the human body is intermediate the first sensing and second sensing electrodes. - View Dependent Claims (2, 3, 4, 5)
-
-
6. A system for non-invasive blood pressure estimation comprising:
-
a. an electrocardiogram (ECG) measuring unit; b. an arterial pulse wave measuring unit in communication with the ECG measuring unit; c. a cuff for measuring blood pressure in communication with the arterial pulse wave measuring unit; d. two or more electrodes connected to the ECG measuring unit; e. an analysis unit connected to the ECG and arterial puke wave measuring unit, the analysis unit comprising, i. an ECG measuring subunit; ii. a cuff pressure and arterial puke wave measuring subunit; iii. a subunit that uses ECG R-peak information for de-trending cuff pressure signal; iv. a subunit that uses ECG R-peak information for isolating arterial pulse waves; v. a subunit for measuring pulse transit time between ECG R-peak and specific points on the arterial pulse wave and mapping the measured pulse transit time with corresponding cuff pressure, obtaining pulse transit time envelopes; vi. a subunit for de-trending cuff pressure signal and finding arterial pulse wave amplitude using ECG R-peak information, and mapping the measured amplitude with corresponding cuff pressure, obtaining an oscillometric envelope; vii. a subunit for analyzing morphology of pulse transit time envelopes, to obtain pulse transit time-based blood pressure estimation; and viii. a subunit for analyzing morphology of the oscillometric envelope, to obtain oscillometric blood pressure estimation. - View Dependent Claims (7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
-
-
17. A method of evaluating diastolic and systolic blood pressure from pulse transit time analysis, comprising the steps of:
-
a. calculating pulse transit time between ECG R-peaks and specific points on arterial pulse waves to obtain pulse transit time envelopes; b. using the maximum of the pulse transit time envelope that is obtained by measuring pulse transit time between ECG R-peaks and bottom of arterial pulse waves, for evaluating diastolic blood pressure; and c. using the maximum of the pulse transit time envelope that is obtained by measuring pulse transit time between ECG R-peaks and top of arterial pulse waves, for evaluating systolic blood pressure. - View Dependent Claims (18, 19)
-
Specification