STIMULUS REGIMENS FOR CARDIOVASCULAR REFLEX CONTROL
First Claim
1. A method of operating an implantable pulse generator, the pulse generator programmed to include multiple modes of operation for stimulating a baroreceptor of a patient as part of a baroreflex therapy, the method comprising:
- applying electrical power from the implantable pulse generator to the baroreceptor according to a programmed mode of operation to achieve a desired physiological response;
automatically monitoring an energy level of a battery associated with the pulse generator; and
automatically changing the mode of operation of the pulse generator to a different mode of operation to reduce an output of electrical power of the pulse generator while maintaining the desired physiological response in response to the energy level of the battery falling below a threshold level.
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Accused Products
Abstract
Baroreflex activation is achieved by providing suitable control signals to a baroreflex activation device. A method comprises establishing a therapy interval within the therapy interval, establishing a plurality of dose intervals, and generating an electrical output signal. The electrical output signal has a time dependence such that the average electrical power applied to the baroreflex activation device differs between first and second portions of at least some dose intervals. Another method comprises establishing a series of therapy interval portions, during at least some therapy intervals, establishing a plurality of burst intervals, and generating an electrical output signal. The electrical output signal has a time dependence such that the average electrical power applied to the baroreflex activation device differs between first and second portions of the therapy intervals and also differs between first and second portions of at least some burst intervals.
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Citations
20 Claims
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1. A method of operating an implantable pulse generator, the pulse generator programmed to include multiple modes of operation for stimulating a baroreceptor of a patient as part of a baroreflex therapy, the method comprising:
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applying electrical power from the implantable pulse generator to the baroreceptor according to a programmed mode of operation to achieve a desired physiological response; automatically monitoring an energy level of a battery associated with the pulse generator; and automatically changing the mode of operation of the pulse generator to a different mode of operation to reduce an output of electrical power of the pulse generator while maintaining the desired physiological response in response to the energy level of the battery falling below a threshold level. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. An implantable pulse generator, comprising:
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a source of electrical energy for applying electrical power to a baroreceptor to achieve a desired physiological response as part of a baroreflex therapy administered to a patient; an energy monitor that monitors an energy level of the implantable pulse generator; and means for changing operation of the implantable pulse generator to adjust an output of electrical power of the implantable pulse generator while maintaining the desired physiological response. - View Dependent Claims (9, 10, 11, 12, 13)
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14. An implantable pulse generator for stimulating a baroreflex system of a patient, comprising:
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a battery for providing electrical energy for use by the implantable pulse generator; a detector that detects an energy level of the battery; and circuitry that generates and delivers stimulation pulses as part of a baroreflex therapy administered to the patient, the pulse generator programmed to include multiple modes of operation for delivery of the stimulation pulses, wherein the modes are responsive to the energy level of the battery, the implantable pulse generator further programmed to change mode of operation at least once to a mode requiring a lower electrical consumption of the battery when the energy level of the battery falls below a threshold energy level. - View Dependent Claims (15, 16, 17, 18, 19)
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20. A method of controlling an implantable pulse generator for baroreflex activation, comprising:
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causing an implantable pulse generator to be manufactured and made available to a user; and providing instructions to the user, the instructions comprising; applying electrical power from an implantable pulse generator to a baroreceptor to achieve a desired physiological response as part of a baroreflex therapy administered to a patient; monitoring an energy level of the implantable pulse generator; and changing operation of the implantable pulse generator to adjust an output of electrical power of the pulse generator, while maintaining the desired physiological response.
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Specification