AUTOMATED PROSTATE TISSUE REFERENCING FOR CANCER DETECTION AND DIAGNOSIS
First Claim
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1. A method of identifying one or more prostate tissue samples in a database that are most similar to a test prostate sample, comprising:
- extracting at least 20 morphological features from the test prostate tissue sample;
determining similarities based on the morphological features between the test prostate sample and a plurality of prostate tissue samples in a database; and
retrieving from the database one or more prostate tissue samples in the database that are the most similar to the test prostate tissue sample.
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Abstract
This application provides to a method for identifying one or more prostate tissue samples in a database that are closest to a test prostate sample, which can be used to aid pathologists when examining prostate tissues to attain reliable and consistent diagnoses of prostate cancer. Also provided are databases and computer algorithms that can be used with such methods.
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Citations
20 Claims
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1. A method of identifying one or more prostate tissue samples in a database that are most similar to a test prostate sample, comprising:
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extracting at least 20 morphological features from the test prostate tissue sample; determining similarities based on the morphological features between the test prostate sample and a plurality of prostate tissue samples in a database; and retrieving from the database one or more prostate tissue samples in the database that are the most similar to the test prostate tissue sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A database comprising:
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digital images of a plurality of prostate cancer tissue samples, normal prostate tissue samples, and BPH tissue samples; and data for at least 20 morphological features for each tissue sample in the database.
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19. A computer-readable storage medium having instructions thereon for performing a method of identifying one or more prostate tissue samples in a database that are closest to a test prostate sample, comprising:
- extracting a plurality of morphological features from a test prostate tissue sample;
retrieving a plurality of morphological features from a plurality of prostate tissue samples in a database; comparing the plurality of morphological features from a test prostate tissue sample to the same plurality of morphological features from the plurality of prostate tissue samples in the database; determining similarities based on the plurality of morphological features between the test prostate sample and a plurality of prostate tissue samples in the database; and retrieving from the database one or more prostate tissue samples in the database that are the most similar to the test prostate tissue sample based on the plurality of morphological features. - View Dependent Claims (20)
- extracting a plurality of morphological features from a test prostate tissue sample;
Specification