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ACETAMINOPHEN-PROTEIN ADDUCT ASSAY DEVICE AND METHOD

  • US 20120301897A1
  • Filed: 08/03/2012
  • Published: 11/29/2012
  • Est. Priority Date: 04/21/2008
  • Status: Abandoned Application
First Claim
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1. A method of determining an amount of APAP-protein adduct in a sample, comprising:

  • a. contacting an amount of the sample with a substrate comprising an anti-APAP antibody coupled to an indicator and further comprising a synthetic APAP-protein adduct; and

    ,b. determining the amount of APAP-protein adduct in the sample by measuring an indicator change caused by inhibition of binding of the synthetic APAP-protein adduct to the anti-APAP antibody coupled to the indicator.

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