TWO-STAGE RECONSTITUTING INJECTOR

• US 20120302989A1
• Filed: 08/13/2012
• Published: 11/29/2012
• Est. Priority Date: 05/03/2006
• Status: Active Grant

• Current Assignee: Antares Pharma Incorporated
• Original Assignee: Antares Pharma Incorporated
• Inventors: KRAMER, Tom, SADOWSKI, Peter L.
• Granted Patent: US 8,696,618 B2
• Time in Patent Office: Days
• US Class Current: 604/500
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/2474 with movable piercing means, e.g. ampoule remains fixed or steady
• CPC Class Codes: A61M 2005/3125 specific display means, e.g. to indicate dose setting
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/2066 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/2466 by piercing without internal pressure increase A61M5/2429 takes precedence
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/3204 Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user

Abstract

An injector (10) for injecting a medicament into a patient. The injector includes a container (18) defining a first chamber (22), which contains a fluid therein, and a second chamber (23). The injector also includes an injection conduit (126) configured for directing the fluid fired from the container into the patient. A transfer mechanism is operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation, and a firing mechanism is operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation. An energy source (62) is in powering association with the firing mechanism to drive firing mechanism in the first and second stages.

Claims

1. An injector for injecting a medicament into a patient, comprising:

a container, the container defining a first chamber containing a fluid, and a second chamber;

an injection conduit in association with the container and configured for directing a fluid fired from the container into the patient;

a transfer mechanism operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation;

a firing mechanism operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation; and

an energy source in powering association with the transfer and firing mechanisms to drive transfer and firing mechanisms in both the first and second stages.

2. The injector of claim 1, further comprising an injection trigger mechanism operably associated with the firing mechanism to operate the firing mechanism in the second stage.

7. The injector of claim 1, further comprising a transfer control that is manually operable to operate the injector in the first stage of operation, which further comprises venting the second chamber.

8. The injector of claim 1, wherein the injection conduit has a position that is fluidly incommunicated with the second chamber, the injector further comprising a transfer control that is manually operable to operate the transfer mechanism in the first stage of operation and to fluidly communicate the injection conduit with the second chamber in the first stage of operation.

9. The injector of claim 8, wherein the transfer control comprises a cap associated with the container and disposed to cover the injection conduit prior to the first stage of operation, which cap is separable from the injection conduit and container after the first stage of operation.

10. The injector of claim 8, wherein the injection conduit comprises a communicating needle portion, the transfer control operable to relatively move the communicating needle portion with respect to the second chamber to pierce the container to fluidly communicate the second chamber with the communicating needle portion in the first stage of operation.

13. The injector of claim 10, wherein the injection conduit comprises a jet nozzle disposed and configured to deliver the fluid by jet injection into the patient during the second stage of operation to pierce the skin of the patient for assisting the injection of the fluid in the second stage.

20. The injector of claim 8, wherein the firing mechanism includes a needle guard that has a protective position disposed for covering a needle of the injection conduit, and an injecting position exposing the needle;

and the cap covering the injection conduit covers the needle and needle guard.

21. The injector of claim 20, wherein the needle guard is configured for causing the firing mechanism to fire the fluid when moved to the retracted position.

3-6. -6. (canceled)

11-12. -12. (canceled)

14-16. -16. (canceled)

17. An injector for injecting a medicament into a patient, comprising:

a container, the container defining a first chamber containing a fluid, and a second chamber;

a firing mechanism configured for transferring the fluid from the first chamber to the second chamber in a first stage of operation, and for firing the fluid from the second chamber in a second stage of operation;

an injection conduit configured for directing the fluid fired from the container into the patient;

an energy source in powering association with the firing mechanism to drive firing mechanism in the first and second stages;

a trigger device associated with the energy source and the firing mechanism and being operable in a first triggering stage which causes the firing mechanism to operate in the first stage of operation, wherein the triggering device is configured such that after the firing mechanism has operated in the first stage of operation, the triggering device is operable in a second triggering stage which causes the firing mechanism to operate in the second stage of operation.

23. The injector of claim 17, wherein the firing mechanism includes a needle guard that has a protective position disposed for covering a needle of the injection conduit, and an injecting position exposing the needle;

and the cap covering the injection conduit covers the needle and needle guard.

18. (canceled)

19. (canceled)

22. An injector for injecting a medicament into a patient, comprising:

a transfer mechanism associable with a container that defines a first and second chambers, the transfer mechanism operable by a user to transfer a fluid from the first chamber to the second chamber in a first stage of operation;

a cap disposed for covering an injection conduit that is associated with the container, the cap being associated with the transfer mechanism such that the cap is retained covering the injection conduit until operation of the transfer mechanism in the first stage of operation; and

a firing mechanism operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation.

24. A method for operating an injector, comprising:

providing an injector that comprises;

an injection conduit configured for injecting fluid into a patient, a cover that covers the injection conduit, a container with first and second chambers, and a firing mechanism configured for expelling fluid from the second chamber through the injection conduit to make an injection;

moving the cover, which activates a transfer mechanism of the injector to transfer a fluid from the first chamber into the second chamber in a first stage of operation; and

blocking operation of the transfer mechanism past the first stage of operation to place the injector in a condition to be manually operated in a second stage of operation in which the firing mechanism expels the fluid to make the injection.