Method and System for Determining Settings for Deep Brain Stimulation
First Claim
1. A method for determining stimulation settings for a brain stimulation probe, the brain stimulation probe comprising a plurality of stimulation electrodes, the method comprising:
- for multiple stimulation electrodes of the plurality of stimulation electrodes;
applying a test current and determining a corresponding patient response, determining a volume of influence based on the test current and a position of the stimulation electrode;
combining the volume of influence and the corresponding patient response with generalized anatomic knowledge of stimulation induced behavior for associating the volume of influence to an anatomic structure;
determining an intersection of the volume of influence and the associated anatomic structure; and
determining an optimal stimulation volume and corresponding stimulation settings for the brain stimulation probe based on the determined intersections.
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Accused Products
Abstract
A method and control system for determining and applying stimulation settings for a brain stimulation probe (10, 12) is provided. The brain stimulation probe (10, 12) comprises a plurality of stimulation electrodes (11). The method comprises for multiple stimulation electrodes (11) of the plurality of stimulation electrodes (11): applying a test current and determining a corresponding patient response, determining a volume of influence based (32, 52, 71, 91) on the test current and a position of the stimulation electrode (11), combining the volume of influence (32, 52, 71, 91) and the corresponding patient response with generalized anatomic knowledge of stimulation induced behavior for associating the volume of influence (32, 52, 71, 91) to an anatomic structure (33, 43, 53), and determining an intersection (41, 51) of the volume of influence (32, 52, 71, 91) and the associated anatomic structure (33, 43, 53). Then, based on the determined intersections (41, 51) an optimal stimulation volume and corresponding stimulation settings for the brain stimulation probe (10, 12) are determined.
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Citations
9 Claims
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1. A method for determining stimulation settings for a brain stimulation probe, the brain stimulation probe comprising a plurality of stimulation electrodes, the method comprising:
for multiple stimulation electrodes of the plurality of stimulation electrodes; applying a test current and determining a corresponding patient response, determining a volume of influence based on the test current and a position of the stimulation electrode; combining the volume of influence and the corresponding patient response with generalized anatomic knowledge of stimulation induced behavior for associating the volume of influence to an anatomic structure; determining an intersection of the volume of influence and the associated anatomic structure; and determining an optimal stimulation volume and corresponding stimulation settings for the brain stimulation probe based on the determined intersections. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A control system for determining stimulation settings for a brain stimulation probe, the brain stimulation probe comprising a plurality of stimulation electrodes, the control system comprising:
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means for applying test currents to the stimulation electrodes, means for obtaining patient responses corresponding to the applied test currents, and a processor being arranged for; determining volumes of influence based on the test currents and positions of the corresponding stimulation electrodes, combining the volumes of influence and the corresponding patient responses with generalized anatomic knowledge of stimulation induced behavior for associating the volumes of influence to anatomic structures, determining intersections of the volumes of influence and the associated anatomic structures, and determining an optimal stimulation volume and corresponding stimulation settings for the brain stimulation probe based on the determined intersections.
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Specification