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Sustained Delivery of Therapeutic Agents to an Eye Compartment

  • US 20120321719A1
  • Filed: 02/25/2011
  • Published: 12/20/2012
  • Est. Priority Date: 02/25/2010
  • Status: Active Grant
First Claim
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1. A method for treating an eye disease or disorder in a patient in need thereof, comprising administering into a part of the eye of the patient, a drug delivery system comprising:

  • a particle comprising a biocompatible core;

    a coating of a hydrophilic polymer or hydrophilic-hydrophobic copolymer or block copolymer associated with the particle, wherein the coating is covalently or non-covalently associated with the particle and presents an uncharged or substantially neutrally charged surface to the environment around the particle; and

    a therapeutically effective amount of a therapeutic agent to treat an eye disease or.disorder.

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