SYSTEM AND METHOD FOR MOTOR AND COGNITIVE ANALYSIS

• US 20120330182A1
• Filed: 11/19/2010
• Published: 12/27/2012
• Est. Priority Date: 11/19/2009
• Status: Active Grant

• Current Assignee: Cleveland Clinic Foundation
• Original Assignee: Cleveland Clinic Foundation
• Inventors: McIntyre, Cameron C., Alberts, Jay L.
• Granted Patent: US 9,653,002 B2
• Time in Patent Office: Days
• US Class Current: 600/558
• CPC Class Codes: A61B 5/162 Testing reaction times
• CPC Class Codes: A61B 5/4082 Diagnosing or monitoring movement diseases, e.g. Parkinson, Huntington or Tourette
• CPC Class Codes: A61B 5/4833 Assessment of subject's compliance to treatment
• CPC Class Codes: A61B 5/4836 Diagnosis combined with treatment in closed-loop systems or methods A61B5/0036 takes precedence
• CPC Class Codes: G09B 23/28 for medicine
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment

Abstract

A cognitive and/or motor skill testing system and method may include a processor that records respective time information for each of multiple positions of a display device that are traced during administration of a test, that determines speed and/or velocity values based on the recorded time information, and that outputs test result information based on the determined values. The test result information may be based on a comparison between a graphed curve of such values to an ideal curve. The positions may correspond to a path between displayed targets whose size and/or distance therebetween depend on past test performance. The system and/or method may output a change expected with a change to therapy parameters for a patient, where the expected change is determined based on changes which occurred in other patients having similar test results and therapy parameters as those of the patient.

Claims

1. A computer-implemented testing method, comprising:

recording, by a processor, respective time information for each of a plurality of positions of a display device that are traced during administration of a test;

determining, by the processor, at least one of a plurality of speed values and a plurality of velocity values based on the recorded time information; and

outputting, by the processor, test result information based on said determined at least one of a plurality of speed values and a plurality of velocity values.

2. The method of claim 1, wherein the output information includes a score computed based on said determined at least one of a plurality of speed values and a plurality of velocity values.

3. The method of claim 2, further comprising:

plotting said determined at least one of a plurality of speed values and a plurality of velocity values as a graph curve; and

comparing at least one slope of the curve to at least one slope of a stored curve;

wherein the score is based on the comparison.

4. The method of claim 1, further comprising:

determining derivatives of the plurality of velocity values, wherein the test result information is based additionally on the derivatives.

5. The method of claim 4, wherein the derivatives include acceleration values.

6. The method of claim 1, further comprising:

generating at least a portion of the test result information by calculating at least one of an average, standard deviation, mean square error, and root mean square error of a difference of (a) said determined at least one of a plurality of speed values and a plurality of velocity values from ideal values, or (b) derivative values of said determined at least one of a plurality of speed values and a plurality of velocity values from ideal derivative values.

7. The method of claim 1, further comprising:

responsive to the trace of the plurality of positions, recording the plurality of traced positions, wherein each of said at least one of a plurality of speed values and a plurality of velocity values are recorded in association with respective ones of the recorded plurality of traced positions.

8. The method of claim 7, wherein the recorded plurality of traced positions are recorded at a rate of approximately 30 Hz.

9. The method of claim 7, wherein the output information includes a graph that plots said at least one of a plurality of speed values and a plurality of velocity values against said recorded plurality of traced positions.

10. The method of claim 7, wherein each of the plurality of traced positions is recorded as a respective pair of an abscissa value and an ordinate value, and, for each pair of abscissa and ordinate values, the abscissa and ordinate values are separately associated with respective ones of said determined at least one of a plurality of speed values and a plurality of velocity values.

11. The method of claim 1, wherein the output information indicates at least one of cognitive ability and motor skill of a user in response to whose movement the plurality of positions are traced.

12. The method of claim 1, wherein:

the display device is part of a patient terminal;

the time information is recorded at a server coupled to the patient terminal via a network; and

the test result information is output at a clinician terminal coupled to the server via the network.

13. The method of claim 12, wherein the network includes the Internet.

14. A computer-implemented testing method, comprising:

displaying in a display device a first target and a second target;

responsive to user input corresponding to a trace of a plurality of positions in the display device, which, in combination, form a path from the first target to the second target, recording, by a processor, respective time information for each of the plurality of positions; and

determining, by the processor, and outputting, information regarding at least one of a cognitive ability and a motor skill of a user based on the recorded time information.

15. The method of claim 14, further comprising:

in accordance with at least a portion of said determined information, modifying at least one of a size of the targets and a distance between the targets.

16. The method of claim 14, further comprising:

in accordance with said determined information, setting at least one of (a) a size of, and (b) a distance between a pair of, additional displayed targets.

17. A computer-implemented testing method, comprising:

displaying in a display device a first target and a second target;

responsive to user input corresponding to a path between the first and second targets, determining, by a processor, at least one of a cognitive ability and a motor skill; and

in accordance with said determined at least one of a cognitive ability and a motor skill, at least one of;

modifying, by the processor, at least one of a size of the targets and a distance between the targets; and

setting, by the processor, at least one of (a) a size of, and (b) a distance between a pair of, additional displayed targets.

18. A computer-implemented testing method, comprising:

in accordance with a test-performance history of a user, selecting, by a processor, at least one of (a) a size of, and (b) a distance between, targets of a testing user interface; and

displaying in a display device the testing user interface including the targets, in accordance with the selected at least one of size and distance.

19. A computer-implemented method for providing testing information, the method comprising:

recording, by a processor, a first at least one therapy parameter applied to a patient;

recording, by the processor, a first test result for the patient in association with the first at least one therapy parameter; and

for a user input proposed change to the at least one therapy parameter to obtain a changed at least one therapy parameter;

searching, by the processor, for a set of at least one patient for each of whom (a) the first test result or a respective second test result that deviates from the first test result by less than a threshold amount is recorded in association with the first at least one therapy parameter or a second at least one therapy parameter that deviates from the first at least one therapy parameter by less than a predetermined threshold amount, and (b) a respective test result is recorded in association with the changed at least one therapy parameter or another respective at least one therapy parameter that deviates from the Changed at least one therapy parameter by less than a predetermined threshold amount; and

outputting, by the processor, information (a) indicative of an expected change to the first test result in response to the proposed change to the at least one therapy parameter, and (b) based on the at least one respective test result recorded for the set of at least one patient in association with said changed at least one therapy parameter or another respective at least one therapy parameter.

20. The method of claim 19, wherein the output information includes the expected changed test result.

21. The method of claim 19, Wherein the output information includes an expected medical condition classification.

22. The method of claim 19, wherein the output information includes an expected change in a medical condition classification.

23. A computer-implemented method for providing testing information, the method comprising:

recording a set of at least one therapy parameter applied to a patient;

recording a result of a test taken by the patient, the recordation being in association with the at least one therapy parameter; and

for a user input proposed change to the at least one therapy parameter, outputting an expected change to the test result for a repeated performance of the test by the patient, based on changes to test results of other patients in response to recorded changes to respective sets of at least one parameter applied to the other patients.

24. A system for analyzing motor and cognitive functions of a patient, comprising:

a display device for providing a graphical user interface (GUI); and

at least one processor configured to;

present an arrangement of graphical targets on the GUI;

generate test data responsive to user-controlled movement relative to the arrangement of graphical interactive targets; and

based on said test data, compute analysis data including at least one of velocity data, acceleration data, speed data, tangential acceleration data, and, for a deviation of one or more lines formed by said movement to one or more respective ideal lines, at least one of an average, a mean square error, and a root mean square error for said deviation.

25. The system of claim 24, wherein the test data includes position data representing a plurality of positions corresponding to said movement and temporal information associated with said plurality of positions.

26. The system of claim 24, wherein the at least one processor is configured to compute a respective dwell time for each of at least one of the graphical targets.

27. The system of claim 24, wherein the processor is configured to:

provide a plurality of different tests during respective test intervals, respective analysis data computed for each; and

output an indication of at least one of motor and cognitive function collectively based on the analysis data computed for the plurality of different tests.

28. The system of claim 27, wherein the plurality of different tests includes at least two of a sevens test, a trail making test, a clock drawing test, a reaction time and subsequent movement task test, a center-out test, an Archimedes spiral test, a judgment of line orientation test, and tests whose complete renderings are dynamically provided as the user takes the tests.

29. The system of claim 24, wherein the at least one processor is configured to generate a patient GUI, a management GUI, and a research GUI depending on an assigned user-authorization level.