NONINVASIVE TREATMENT OF BLOOD VESSELS

• US 20120330197A1
• Filed: 08/31/2012
• Published: 12/27/2012
• Est. Priority Date: 10/07/2004
• Status: Abandoned Application

• Current Assignee: Guided Therapy Systems Llc
• Original Assignee: Guided Therapy Systems Llc
• Inventors: Makin, Inder Raj S., Slayton, Michael H., Barthe, Peter G.
• Application Number:
  US13/601,742
• Publication Number:
  US 20120330197A1
• Time in Patent Office: Days
• US Class Current: 601/3
• CPC Class Codes: A61B 2017/00756 Port wine stains
• CPC Class Codes: A61B 8/4281 characterised by sound-transmitting media or devices for coupling the transducer to the tissue
• CPC Class Codes: A61B 8/429 characterised by determining or monitoring the contact between the transducer and the tissue
• CPC Class Codes: A61N 2007/0008 Destruction of fat cells
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

A non-invasive method and system for using ultrasound energy for the treatment of conditions resulting from vascular disorders is provided. In one embodiment, an image-treatment approach can be used to locate the blood vessel to be treated and then to ablate it non-invasively, while also monitoring the progress of the treatment. In another embodiment, a transducer is configured to deliver ultrasound energy to the regions of the superficial tissue (e.g., skin) such that the energy is deposited at the particular depth at which the vascular malformations are located below the skin surface. The ultrasound transducer can be driven at a number of different frequency regimes such that the depth and shape of energy concentration can match the region of treatment.

Claims

1. A non-invasive method for treating a spider vein, the method comprising:

positioning an ultrasound probe on a skin surface, the ultrasound probe comprising at least one ultrasound therapy element;

imaging a region of interest under the skin surface, wherein the region of interest comprises a spider vein;

using the at least one ultrasound therapy element to create a plurality of thermal lesions in at least a portion of the spider vein in the region of interest,

wherein the at least one ultrasound therapy element is configured to deliver ultrasound energy at a depth of up to about 7 mm below the skin surface.

2. The method of claim 1,

wherein the at least one ultrasound therapy element delivers energy at a frequency in a range of about 2 MHz to about 20 MHz,

wherein the step of imaging the region of interest comprises ultrasound imaging, and

further comprising moving the at least one ultrasound therapy element along a linear path using an automated motion mechanism.

3. The method of claim 1, wherein the using the at least one ultrasound therapy element comprises adjustable control of spatial parameters and temporal parameters of the ultrasound probe to generate thermal lesions of specifically targeted shapes, sizes or orientations in at least a portion of the region of interest.

4. The method of claim 1, wherein the using the at least one ultrasound therapy element comprises using a motion mechanism coupled to the at least one ultrasound therapy element within the ultrasound probe.

5. The method of claim 1, wherein the using the at least one ultrasound therapy element comprises using electronic phase focusing of the at least one ultrasound therapy element to position a focus for delivery of the energy to create a thermal lesion in the spider vein.

6. The method of claim 1, wherein the step of creating the plurality of thermal lesions comprises producing a discrete locus of spaced conformal lesions based on adjustable control of spatial parameters and temporal parameters.

7. The method of claim 1, wherein the step of creating the plurality of thermal lesions comprises producing a one-, two- or three-dimensional matrix of spaced lesions in the spider vein.

8. The method of claim 1, further comprising monitoring the spider vein for further planning, assessing of results, or providing feedback.

9. The method of claim 1, wherein the ultrasound energy is delivered at a frequency in a range of about 2 MHz to about 20 MHz.

10. A method for providing treatment of a vascular disorder, the method comprising:

targeting therapeutic acoustic waves, via at least one ultrasound treatment element housed within an ultrasound probe, through a skin surface to treat a blood vessel under the skin surface; and

activating phase focusing of the at least one ultrasound treatment element for controllably creating a plurality of thermal lesions along a line at a depth up to about 7 mm below the skin surface,

wherein the activating phase focusing comprises varying at least one electronic time delay controlled by a control system in communication with the ultrasound probe,

wherein the plurality of thermal lesions treats a vascular disorder in the blood vessel, and

wherein the vascular disorder is selected from the group consisting of a spider vein, a hemangioma and a port wine stain.

11. The method of claim 10, wherein the ultrasound energy is delivered at a frequency in a range of about 2 MHz to about 20 MHz.

12. The method of claim 10, further comprising imaging a region below the skin surface.

13. The method of claim 10, further comprising moving the treatment element along the line using an automated motion mechanism.

14. The method of claim 10, wherein the plurality of thermal lesions comprise a matrix of spaced treatment spots that are spaced using an automated motion mechanism.

15. A method for treating a vascular disorder, the method comprising:

positioning an ultrasound probe on a skin surface proximate to at least one aberrant blood vessel;

wherein the ultrasound probe comprises an ultrasound therapy element configured to deliver ultrasound energy at a frequency in a range of about 2 MHz to about 20 MHz;

selecting an ultrasound probe configuration based on at least one of a spatial parameter and a temporal parameter;

verifying the at least one of a spatial parameter and a temporal parameter of the probe; and

using a motion mechanism to move the ultrasound therapy element to create a plurality of thermal lesions in at least a portion of the aberrant blood vessel; and

using an ultrasound imaging element to image a region of interest under the skin surface comprising the aberrant blood vessel.

16. The method of claim 15, wherein the imaging element is configured for at least one of Doppler flow monitoring and color flow monitoring.

17. The method of claim 15, wherein the using the motion mechanism to move the ultrasound therapy element comprises controlling spatial parameters and temporal parameters of the probe to generate conformal lesions of specifically targeted shapes, sizes and orientations.

18. The method of claim 15, wherein the using the motion mechanism comprises producing a matrix of spaced treatment spots comprising at least one of a two-dimensional and three-dimensional matrix of lesions in the region of interest along a scanned pattern created by scanning of the probe, wherein the producing the matrix of spaced treatment spots comprises producing a discrete locus of spaced lesions based on adjustable control of spatial parameters and temporal parameters.

19. The method of claim 15, further comprising treating the blood vessel with any one in the group consisting of cavitational, hydrodynamic, and resonance induced tissue effects.

20. The method of claim 15, wherein the plurality of thermal lesions comprise a matrix of spaced treatment spots that are spaced using the motion mechanism.