AEROSOLIZED DAPSONE AS A THERAPY FOR INFLAMMATION OF THE AIRWAY AND ABNORMAL MUCOCILIARY TRANSPORT
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Abstract
Aerosolized dapsone (or alternatively, an aqueous formulation of dapsone) is used to treat airway inflammation, particularly chronic neutrophil-dominated inflammation. Diseases that may be prevented or treated by the methods include chronic obstructive pulmonary diseases (COPDs), asthma, cystic fibrosis, and others.
5 Citations
27 Claims
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1-8. -8. (canceled)
- 9. A method of preventing or treating inflammation in an airway of a patient in need thereof, comprising administering to said airway of said patient a pharmaceutical composition comprising dapsone and a pharmaceutically acceptable carrier suitable for use in inhalation.
- 25. A pharmaceutical composition for administration by inhalation for preventing or treating inflammation in an airway of a patient in need thereof, comprising a therapeutically effective amount of dapsone and a pharmaceutically acceptable carrier suitable for use in inhalation.
Specification