METHOD FOR TREATING AN AORTIC VALVE
First Claim
1. A method for treating a damaged or diseased native aortic valve, the method comprising:
- percutaneously inserting a delivery catheter into a vasculature of a patient;
loading a prosthetic heart valve in a contracted configuration into the delivery catheter, the prosthetic heart valve comprising a one-way valve structure and a one-piece, nitinol, tubular stent body comprising, from an inflow end to an outflow end thereof, an anchoring section, a sinus section, and an outflow section, the one-way valve structure disposed within the sinus section;
advancing the prosthetic heart valve through the delivery catheter;
positioning a distal end of the delivery catheter proximal to a native aortic valve;
retracting the delivery catheter relative to a prosthetic heart valve, thereby delivering the prosthetic heart valve from the distal end of the delivery catheter into an annulus of the native aortic valve;
allowing the annulus anchoring section of the tubular stent body to self-expand into an expanded configuration in the annulus of the native aortic valve, thereby anchoring the annulus anchoring section in the annulus and compressing native leaflets of the aortic valve; and
allowing the outflow section of the tubular stent body to self-expand in an ascending aorta to an expanded configuration, the outflow section flaring outwardly from the sinus section, the outflow section conforming to and contacting the ascending aorta, the outflow section being flexible to accommodate movement of the ascending aorta, thereby stabilizing the prosthetic valve,whereinthe sinus section of the tubular stent body comprises a plurality of sinus apertures and the outflow section comprises a plurality of diamond-shaped apertures,the annulus anchoring section is more rigid than the flared outflow section, andthe valve structure comprises three pericardium membranes disposed within the sinus section of the tubular stent body, each membrane comprising a free edge and an outer edge portion, the free edges of the membranes coapting with each other to define a one-way valve, the outer edge portions of the membranes sutured to the sinus section, the free edges meeting at the sinus section at axially extending commissures.
1 Assignment
0 Petitions
Accused Products
Abstract
Expandable, percutaneously deployable, prosthetic heart valves and systems for minimally invasive replacement of damaged or diseased native aortic valves comprise an expandable, tubular stent body and a unidirectional valve assembly. Embodiments of the stent body comprise an annulus anchoring section, a sinus section, and an outflow section, with the outflow section flared outwardly from the sinus section in an expanded configuration. Embodiments of the stent body are self-expanding, comprising, for example nitinol. The valve assembly disposed within the sinus section of the stent body and sutured thereto. Embodiments of the valve assembly comprise three leaflets, each leaflet comprising a curved outer edge sutured to the sinus section of the stent body, and a coapting free edge. Embodiments of the valve leaflets comprise pericardium, for example, porcine pericardium. Embodiments of the prosthetic heart valve have a contracted configuration dimensioned for percutaneous delivery thereof.
12 Citations
17 Claims
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1. A method for treating a damaged or diseased native aortic valve, the method comprising:
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percutaneously inserting a delivery catheter into a vasculature of a patient; loading a prosthetic heart valve in a contracted configuration into the delivery catheter, the prosthetic heart valve comprising a one-way valve structure and a one-piece, nitinol, tubular stent body comprising, from an inflow end to an outflow end thereof, an anchoring section, a sinus section, and an outflow section, the one-way valve structure disposed within the sinus section; advancing the prosthetic heart valve through the delivery catheter; positioning a distal end of the delivery catheter proximal to a native aortic valve; retracting the delivery catheter relative to a prosthetic heart valve, thereby delivering the prosthetic heart valve from the distal end of the delivery catheter into an annulus of the native aortic valve; allowing the annulus anchoring section of the tubular stent body to self-expand into an expanded configuration in the annulus of the native aortic valve, thereby anchoring the annulus anchoring section in the annulus and compressing native leaflets of the aortic valve; and allowing the outflow section of the tubular stent body to self-expand in an ascending aorta to an expanded configuration, the outflow section flaring outwardly from the sinus section, the outflow section conforming to and contacting the ascending aorta, the outflow section being flexible to accommodate movement of the ascending aorta, thereby stabilizing the prosthetic valve, wherein the sinus section of the tubular stent body comprises a plurality of sinus apertures and the outflow section comprises a plurality of diamond-shaped apertures, the annulus anchoring section is more rigid than the flared outflow section, and the valve structure comprises three pericardium membranes disposed within the sinus section of the tubular stent body, each membrane comprising a free edge and an outer edge portion, the free edges of the membranes coapting with each other to define a one-way valve, the outer edge portions of the membranes sutured to the sinus section, the free edges meeting at the sinus section at axially extending commissures.
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2. A method for treating a damaged or diseased native aortic valve, the method comprising:
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inserting a delivery catheter into a patient; loading a prosthetic heart valve in a contracted configuration into the delivery catheter, the prosthetic heart valve comprising a one-way valve structure and a one-piece, tubular stent body comprising, from an inflow end to an outflow end thereof, an anchoring section, a sinus section, and an outflow section, the one-way valve structure disposed within the sinus section; positioning a distal end of the delivery catheter proximal to a native aortic valve; retracting the delivery catheter relative to a prosthetic heart valve, thereby delivering the prosthetic heart valve from the distal end of the delivery catheter into an annulus of the native aortic valve; expanding the annulus anchoring section of the tubular stent body into an expanded configuration in the annulus of the native aortic valve, thereby anchoring the annulus anchoring section in the annulus and compressing native leaflets of the aortic valve; and expanding an outflow section of the tubular stent body into an expanded configuration in an ascending aorta, the outflow section flaring outwardly from the sinus section, the outflow section conforming to and contacting the ascending aorta, thereby stabilizing the prosthetic valve. - View Dependent Claims (3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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Specification