SYSTEMS & METHOD FOR DETERMINING BLOOD COMPONENT CONCENTRATION
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Accused Products
Abstract
A system (1) for determining blood component concentration in vivo, the system (1) comprising: a probe (3) having an optical component and an electrical component, said optical component comprising a light source (9) for illuminating tissue (5) of a subject, said tissue (5) including a light absorbing blood component of interest, and a light detector (11) configured to detect light that has been emitted by said source (9) and has passed through said tissue (5); said electrical component comprising electrodes (13, 15) for applying an electric field across said tissue (5); and a control module (4) configured to receive signals from said light detector (11) that are representative of the intensity of light detected by the detector (11) and to receive signals from said electrodes (13, 15) that are representative of the capacitance of said tissue (5); wherein the amplitude of said signals varies periodically with the subject'"'"'s cardiac cycle, and said control module (4) comprises a processor (35) operable to determine from said signals the concentration of said blood component in said tissue (5).
5 Citations
50 Claims
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1-30. -30. (canceled)
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31. A system for determining blood component concentration in vivo, the system comprising:
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a probe having an optical component and an electrical component, said optical component comprising a light source for illuminating tissue of a subject, said tissue including a light absorbing blood component of interest, and a light detector configured to detect light that has been emitted by said source and has passed through said tissue;
said electrical component comprising electrodes for applying an electric field across said tissue; anda control module configured to receive signals from said light detector that are representative of the intensity of light detected by the detector and to receive signals from said electrodes that are representative of the capacitance of said tissue; wherein; the amplitude of the signals representative of the intensity of light detected by said light detector varies periodically with the subject'"'"'s cardiac cycle and is indicative of variations in the amount of blood component in the tissue during the cardiac cycle, the amplitude of the signals from said electrodes varies with the subject'"'"'s cardiac cycle and the varying capacitance is indicative of variations in the total blood volume in said tissue, and said control module comprises a processor configured to compare variations in intensity amplitude to variations in capacitance amplitude to derive a measure of the concentration of the blood component in the tissue during the cardiac cycle. - View Dependent Claims (32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49)
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50. A method of determining blood component concentration in vivo, the method comprising:
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operating a light source to illuminate tissue of a subject, said tissue including a light absorbing blood component of interest, operating a light detector to detect light that has been emitted by said source and has passed through said tissue; applying an electric field across said tissue via a set of electrodes; receiving signals from said light detector that are representative of the intensity of light detected by the detector and receiving signals from said electrodes that are representative of the capacitance of said tissue;
wherein the amplitude of the signals representative of the intensity of light detected by said light detector varies periodically with the subject'"'"'s cardiac cycle and is indicative of variations in the amount of blood component in the tissue during the cardiac cycle, the amplitude of the signals from said electrodes varies with the subject'"'"'s cardiac cycle and the varying capacitance is indicative of variations in the total blood volume in said tissue, andoperating a processor to compare variations in intensity amplitude to variations in capacitance amplitude to derive a measure of the concentration of the blood component in the tissue during the cardiac cycle.
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Specification