Integrated Optical Neural Probe
First Claim
1. A neural probe, comprising:
- a substrate comprising one or more elongated shanks for penetrating neural tissue, each elongated shank comprising a proximal end and a distal end;
at least one optical source integral to the neural probe for illuminating the neural tissue; and
one or more microelectrodes located proximate the distal end of one or more of the elongated shanks for monitoring neuronal activity.
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Abstract
In certain embodiments, a neural probe comprises a substrate comprising elongated shanks for penetrating neural tissue, each comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and microelectrodes located proximate the distal end of the elongated shanks for monitoring neuronal activity. In certain embodiments, a method of monitoring neuronal activity comprises implanting the neural probe into a test subject such that the elongated shanks protrude into neural tissue of the test subject; illuminating the neural tissue with the at least one optical source; and measuring neuronal activity in response to illuminating the neural tissue. In certain embodiments, a device comprises a semiconductor chip; at least one optical source integral to the semiconductor chip; and sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source.
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Citations
20 Claims
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1. A neural probe, comprising:
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a substrate comprising one or more elongated shanks for penetrating neural tissue, each elongated shank comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and one or more microelectrodes located proximate the distal end of one or more of the elongated shanks for monitoring neuronal activity. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A device, comprising:
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a semiconductor chip; at least one optical source integral to the semiconductor chip; and one or more sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source. - View Dependent Claims (20)
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Specification