INTRAVASCULAR THROMBOEMBOLECTOMY DEVICE AND METHOD USING THE SAME

• US 20130030460A1
• Filed: 07/26/2011
• Published: 01/31/2013
• Est. Priority Date: 07/26/2011
• Status: Abandoned Application

• Current Assignee: Scientia Vascular, LLC
• Original Assignee: Scientia Vascular, LLC
• Inventors: Marks, Michael P., Que, Like
• Application Number:
  US13/191,306
• Publication Number:
  US 20130030460A1
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2090/08021 of the patient or his organs

Abstract

A device and a method for increasing or restoring a flow in a body lumen are provided. The device and the method may treat conditions related to a stroke, such as an ischemic stroke, by removing an occlusion from a blood vessel and/or reopen a blood vessel. The device may comprise a pusher tube and an expandable compartment. The expandable compartment may comprise a control element, a reconfigurable element, and supportive element. The supportive element is configured to adjust a radial force and a configuration of the reconfigurable element, thereby allowing highly efficient removal of an occlusion from a blood vessel and/or reopen a blood vessel with least or no damage to the body lumen.

Claims

1. A device for use in a body lumen comprising:

a pusher tube and an expandable compartment;

wherein the expandable compartment comprises;

a control element comprising a proximal end and a distal end;

a reconfigurable element, said reconfigurable element being associated with a supportive element and the control element; and

a supportive element, said supportive element being associated with the control element and the reconfigurable element, wherein the supportive element is configured to adjust a radial force and a configuration of the reconfigurable element.

2. The device according to claim 1, wherein the control element comprises a wire, cable, or braid.

3. The device according to claim 1, wherein the reconfigurable element and/or the supportive element comprise(s) a plurality of wires.

4. The device according to claim 3, wherein the reconfigurable element can self expand into a relaxed expandable state to form a compartment or basket.

5. The device according to claim 4, wherein the reconfigurable element comprises a plurality of cells, and a size of a cell and a thickness of wires surrounding the cell vary within the reconfigurable element.

6. The device according to claim 1, wherein the supportive element is in a form of strut that is manufactured from a same piece of material as the reconfigurable element and automatically connected to the reconfigurable element.

7. The device according to claim 1, wherein the supportive element is in a form of wire mesh or a braid.

8. The device according to claim 1, wherein the pusher tube is connected to the expandable compartment.

9. The device according to claim 1, wherein the control element is surrounded by the pusher tube and can move freely inside the pusher tube.

10. The device according to claim 1, wherein the supportive element comprises a first configuration and a second configuration, said first configuration having a smaller angle between the supporting element and the control element than the angle in the second configuration.

11. The device according to claim 1, wherein the supportive element comprises a first configuration and a second configuration, said first configuration having an outer diameter which is smaller than an outer diameter of the second configuration.

12. The device according to claim 10 and 11, wherein projection of the control element to a distal direction causes transition of the supportive element to the first configuration such that the radial force of the reconfigurable element is reduced.

13. The device according to claim 10 and 11, wherein projection of the control element to a proximal direction causes transition of the supportive element to the second configuration such that the radial force of the reconfigurable element is increased.

14. The device according to claim 1, wherein the device is configured to remove an occlusion blocking a blood vessel, to open a blocked section of a blood vessel and/or to increase a flow in a blood vessel.

15. The device according to claim 1, wherein a distal end of the reconfigurable element is joined forming a closed-end reconfigurable element, or not jointed forming an open-end reconfigurable element.

16. The device according to claim 1, wherein the sides of the reconfigurable element are joined forming a closed-sided reconfigurable element, or not joined forming an open-sided reconfigurable element.

17. The device according to claim 1, wherein the supportive element comprises a plurality of wires, and said wires are extendible between the proximal and distal ends, and substantially surrounded by the reconfigurable element.

18. The device according to claim 1, wherein the reconfigurable element and the supportive element are in a form of wire mesh, which can be extendible between the proximal and distal ends, and the supportive element is substantially surrounded by the reconfigurable element, thereby forming a double-layered reconfigurable element.

19. The device according to claim 1, wherein the reconfigurable element comprises a plurality of linear wires aligned substantially in parallel and a plurality of wires in a substantially circular form, and the supportive element comprises at least two wires that is associated with the reconfigurable element and the control element, thereby forming an umbrella-shaped expandable compartment.

20. The device according to claim 1, wherein a distal end of the reconfigurable element and a distal end of the supportive element are not connected and move independently.

21. The device according to claim 1, wherein an atraumatic flexible coil is attached to the distal tip of the reconfigurable element.

22. The device according to claim 1, wherein the device comprises a distal expandable structure and a proximal expandable structure.

23. The device according to claim 22, wherein the first expandable structure comprises a reconfigurable element, a control element, and optionally a supportive element.

24. The device according to claim 22, wherein said the second expandable structure comprises a reconfigurable element and optionally an enclosing element.

25. The device according to claim 22, wherein a distance between the distal and proximal expandable structures is adjustable.

26. A method of removing an occlusion present in a first position of a blood vessel comprising:

introducing the device according to claim 1 into the blood vessel;

locating the device at the first position of the blood vessel;

adjusting the radial force and/or configuration of the reconfigurable element of the device; and

removing the occlusion from the first location.

27. The method according to claim 26 wherein removing the occlusion further comprises one or more selected from the group consisting of:

engaging the occlusion at least partially with the device;

disassembling the occlusion into small-sized debris and collecting at least part of the debris; and

expanding the area of the blood vessel.

28. The method according to claim 26 wherein the method is configured to be applied for treatment of stroke.

29. A method of increasing a flow in a blood vessel comprising:

introducing the device according to claim 1 into the blood vessel;

locating the device at about the first position of the blood vessel that is in need of increasing the flow; and

adjusting the radial force and/or configuration of the reconfigurable element of the device so as to expand an area of the first position.

30. A method of removing an occlusion present in a first position of a blood vessel comprising:

introducing a device according to claim 1 into the blood vessel;

locating the device at about the first position of the blood vessel;

supporting the expanded status of the reconfigurable element by extending a support element associated with the reconfigurable element by proximal movement of the control element;

further supporting a more expanded status of the reconfigurable element by extending a support element associated with the reconfigurable element by proximal movement of the control element;

grabbing the occlusion with the reconfigurable element in its expanded status;

shifting the configuration of the reconfigurable element toward a more relaxed status by distally moving the control element; and

removing the occlusion from the first location.

31. A method of removing an occlusion present in a first position of a blood vessel comprising:

introducing a device according to claim 22 into the blood vessel;

locating the device distal to the position of the blood vessel;

pulling the pusher tube proximally to grab the occlusion between the two expandable structures in its expanded status;

supporting the expanded status of the reconfigurable element by extending a support element associated with the reconfigurable element by proximal movement of the control element;

grabbing the clot with the proximal expandable structure;

catching the clot debris with the distal expendable structure;

optionally retrieving the device while pulling the control element to increase the radial force of the expendable structure and further support an expanded status of the expandable structure; and

removing the occlusion from the first location.