INTRAVASCULAR THROMBOEMBOLECTOMY DEVICE AND METHOD USING THE SAME

• US 20130030461A1
• Filed: 07/06/2012
• Published: 01/31/2013
• Est. Priority Date: 07/26/2011
• Status: Active Grant

• Current Assignee: Scientia Vascular, LLC
• Original Assignee: Thrombx Medical, Inc.
• Inventors: Marks, Michael P., Que, Like
• Granted Patent: US 11,026,708 B2
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61B 17/22032 having inflatable gripping elements balloon catheters A61M25/10
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/00778 Operations on blood vessels A61B2017/22097, A61B2017/320741 take precedence
• CPC Class Codes: A61B 2017/22038 with a guide wire
• CPC Class Codes: A61B 2017/22051 with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation A61B2017/22048, A61B2017/3486 take precedence
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2230/0076 ellipsoidal or ovoid
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2230/0093 Umbrella-shaped, e.g. mushroom-shaped

Abstract

A device and a method for increasing or restoring a flow in a body lumen are provided. The device and the method may treat conditions related to a stroke, such as an ischemic stroke, by removing an occlusion from a blood vessel and/or reopen a blood vessel. The device may comprise a tubing compartment, a central wire, and an engaging compartment. The engaging compartment may comprise a distal engaging element and a proximal engaging element. A clot or occlusion present in the body lumen such as an artery may be engaged in and/or between the distal and proximal engaging elements. Further, the positions of one or both of the engaging elements and the distance therebetween can be adjusted to ensure the engagement of the clot or occlusion.

Claims

1. A device for use in a body lumen comprising:

a microcatheter comprising a distal end and a proximal end;

a tubing compartment;

a central wire; and

an engaging compartment,

wherein the engaging compartment comprises;

a proximal engaging element; and

a distal engaging element,

wherein the distal engaging element is an expandable element that is associated with the central wire, and a distance between the proximal engaging element and the distal engaging element is adjustable.

2. The device according to claim 1, wherein the distal engaging element comprises a plurality of wires or struts forming a stent.

3. The device according to claim 1, wherein the distal engaging element is fixed with the central wire extending to a proximal end of the device, thereby a location of the distal engaging element in the body lumen is controlled by movement of the central wire.

4. The device according to claim 1, wherein the proximal engaging element is an expandable element comprising a plurality of wires or struts and can expand into a funnel or cone shaped structure.

5. The device according to claim 1, wherein the proximal engaging element is associated with the central wire and moves along the central wire.

6. The device according to claim 5, wherein the proximal engaging element is fixed with the tubing compartment extending to a proximal end of the device, thereby a location of the proximal engaging element in the body lumen is controlled by movement of the tubing compartment.

7. The device according to claim 5, wherein the proximal engaging element is not fixed with the tubing compartment and configured to freely move along the central wire.

8. The device according to claim 1, wherein the proximal engaging element is located at the distal end of the microcatheter.

9. The device according to claim 8, wherein the proximal engaging element is not an integral part of the microcatheter and fixed at the distal end of the microcatheter.

10. The device according to claim 8, wherein the proximal engaging element is an inflatable or engaging element.

11. The device according to claim 8, wherein the proximal engaging element is an integral part of the microcatheter.

12. The device according to claim 11, wherein the proximal engaging element comprises a portion of the distal end of the microcatheter, said portion being configured to change a shape depending on a pressure applied to the distal end of the microcatheter.

13. The device according to claim 11, wherein the proximal engaging element comprises a portion of the distal end of the microcatheter comprising a microcather tip and a layer of thin tubing that covers the microcatheter tip, wherein at least part of said proximal engaging element is configured to change a shape when the layer of thin tubing is removed.

14. The device according to claim 1, wherein the tubing compartment comprises a pusher tubing and a connecting tubing.

15. The device according to claim 1, wherein the tubing compartment is made from one piece of tubing with variable stiffness such that a distal end of the tubing compartment is soft and flexible so the device can pass tortuous anatomy while a proximal end of the tubing compartment is stiff to enhance pushability of the device.

16. The device according to claim 1, wherein the central wire comprises a wire, a cable, or a braid.

17. The device according to claim 1, wherein the distance between the proximal engaging element and the distal engaging element is adjustable approximately in range of 0 to 50 mm.

18. The device according to claim 1, wherein the proximal engaging element comprises a distal end facing the distal engaging element, said distal end of the proximal engaging element being bended, rounded, or smoothed.

19. The device according to claim 1, wherein the proximal engaging element comprises a distal end facing the distal engaging element, said distal end of the proximal engaging element being configured not to be in direct contact with a surface of the body lumen.

20. A method of removing at least part of an occlusion from a first location in a body lumen comprising:

introducing the device according to claim 1 into the body lumen;

locating the device at about the first location;

engaging the at least part of the occlusion with the engaging element; and

removing the engaged occlusion from the first location.

21. The method according to claim 20, wherein said engaging comprises:

adjusting the position of one or both of the proximal engaging element and the distal engaging element so as to engage at least part of the occlusion with the proximal engaging element and/or the distal engaging element.

22. The method of according to claim 20, wherein said engaging comprises:

adjusting the distance between the proximal engaging element and the distal engaging element so as to engage the at least part of the occlusion between the proximal engaging element and the distal engaging element.

23. The method of according to claim 20, wherein the method further comprises:

after engaging, locking the position of one or both of the proximal engaging element and the distal engaging element.

24. The method according to claim 20, wherein, in said engaging, at least part of the occlusion is engaged with any component selected from the group consisting of the surface of the body lumen, the microcatheter, the tubing compartment, the proximal engaging element, the distal engaging element, and any combinations thereof.