Flexible and Stretchable Electronic Systems for Epidermal Electronics
First Claim
Patent Images
1. A device for establishing an interface with a skin of a subject, the device comprising:
- a flexible or stretchable substrate having an average modulus less than or equal to 1 MPa;
a flexible or stretchable electronic circuit supported by the flexible or stretchable substrate, wherein the flexible or stretchable electronic circuit comprises a plurality of sensors, actuators or both sensors and actuators provided in an array including one or more inorganic semiconductor circuit elements or electrodes, or a combination of inorganic semiconductor circuit elements and electrodes; and
a barrier layer encapsulating at least a portion of the flexible or stretchable electronic circuit, the flexible or stretchable substrate, or both the flexible or stretchable electronic circuit and the flexible or stretchable substrate;
wherein the flexible or stretchable substrate, barrier layer and the electronic circuit provide a net bending stiffness, thickness, effective elastic modulus, and areal mass density of the device such that the device establishes conformal contact with the skin of the subject.
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Abstract
Provided herein are skin-mounted biomedical devices and methods of making and using biomedical devices for sensing and actuation applications. For example, flexible and/or stretchable biomedical devices are provided, including electronic devices useful for establishing conformal contact with the skin of a subject. Devices disclosed herein can comprise a plurality of sensing and/or actuating devices provided as part of a skin-mounted flexible or stretchable electronic circuit.
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Citations
88 Claims
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1. A device for establishing an interface with a skin of a subject, the device comprising:
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a flexible or stretchable substrate having an average modulus less than or equal to 1 MPa; a flexible or stretchable electronic circuit supported by the flexible or stretchable substrate, wherein the flexible or stretchable electronic circuit comprises a plurality of sensors, actuators or both sensors and actuators provided in an array including one or more inorganic semiconductor circuit elements or electrodes, or a combination of inorganic semiconductor circuit elements and electrodes; and a barrier layer encapsulating at least a portion of the flexible or stretchable electronic circuit, the flexible or stretchable substrate, or both the flexible or stretchable electronic circuit and the flexible or stretchable substrate; wherein the flexible or stretchable substrate, barrier layer and the electronic circuit provide a net bending stiffness, thickness, effective elastic modulus, and areal mass density of the device such that the device establishes conformal contact with the skin of the subject. - View Dependent Claims (2, 3, 4, 5, 9, 10, 14, 16, 18, 19, 20, 22, 23, 24, 25, 26, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 46, 47, 48, 49, 50, 51, 52, 54, 56, 57, 59, 60, 61, 78, 79, 80, 81, 82)
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6-8. -8. (canceled)
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11-13. -13. (canceled)
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15. (canceled)
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17. (canceled)
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21. (canceled)
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27. (canceled)
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44-45. -45. (canceled)
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53. (canceled)
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55. (canceled)
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58. (canceled)
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62-77. -77. (canceled)
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83. A device for establishing an interface with a skin of a subject, the device comprising:
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a flexible or stretchable electronic circuit comprising an array of sensors, actuators, or sensors and actuators, wherein elements of the array are interconnected by serpentine interconnects, said flexible or stretchable electronic circuit configured for conformal contact with the skin of a subject; a contact layer between the flexible or stretchable electronic circuit and the skin to provide conformal contact between the flexible or stretchable electronic circuit and the skin; and a cover layer that covers the flexible or stretchable electronic circuit when the device is in conformal contact with skin. - View Dependent Claims (84, 85, 86)
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87. A method of interfacing an electronic device with a skin of a subject, the method comprising:
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applying a liquid bandage on the skin to form a contact layer on the skin; contacting a conformable electronic device with the contact layer on the skin to establish conformal contact between the conformable electronic device and the underlying skin, wherein the conformable electronic device comprises a plurality of sensors interconnected by serpentine interconnects; and applying a liquid bandage over the conformable electronic device in conformal contact with the skin to form a cover layer.
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88-89. -89. (canceled)
Specification