PECVD COATING METHODS FOR CAPPED SYRINGES, CARTRIDGES AND OTHER ARTICLES

• US 20130041241A1
• Filed: 10/12/2012
• Published: 02/14/2013
• Est. Priority Date: 07/02/2009
• Status: Active Grant

• Current Assignee: SiO2 Medical products Inc.
• Original Assignee: SiO2 Medical products Inc.
• Inventors: Felts, John T., Fisk, Thomas E., Kinney, Shawn, Sagona, Peter J., Weikart, Christopher, Hunt, Benjamin, Raiche, Adrian, Fitzpatrick, Brian, Stevenson, Adam
• Granted Patent: US 9,458,536 B2
• Time in Patent Office: Days
• US Class Current: 600/364
• CPC Class Codes: A61B 5/1405 Devices for taking blood samples devices for taking samples of other body liquids A61B10/0045
• CPC Class Codes: A61B 5/15003 for venous or arterial blood
• CPC Class Codes: A61B 5/150236 Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
• CPC Class Codes: A61B 5/150244 Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
• CPC Class Codes: A61B 5/150274 Manufacture or production processes or steps for blood sampling devices
• CPC Class Codes: A61B 5/150389 Hollow piercing elements, e.g. canulas, needles, for piercing the skin
• CPC Class Codes: A61B 5/150519 Details of construction of hub, i.e. element used to attach the single-ended needle to a piercing device or sampling device
• CPC Class Codes: A61B 5/150595 by snap-lock (i.e. based on axial displacement)
• CPC Class Codes: A61B 5/150717 manually removed
• CPC Class Codes: A61B 5/150755 Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
• CPC Class Codes: A61B 5/153 Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
• CPC Class Codes: A61B 5/154 Devices using pre-evacuated means
• CPC Class Codes: A61L 31/08 Materials for coatings
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: B05D 7/22 to internal surfaces, e.g. of tubes
• CPC Class Codes: C23C 16/045 Coating cavities or hollow spaces, e.g. interior of tubes; Infiltration of porous substrates
• CPC Class Codes: C23C 16/401 containing silicon
• CPC Class Codes: C23C 16/505 using radio frequency discharges
• CPC Class Codes: C23C 16/52 Controlling or regulating the coating process C23C16/45557, C23C16/279 take precedence
• CPC Class Codes: C23C 16/54 Apparatus specially adapted for continuous coating
• CPC Class Codes: G01M 3/329 : for verifying the internal pressure of closed containers
• CPC Class Codes: G01N 2033/0096 : testing material properties on thin layers or coatings

Abstract

A method is disclosed in which a vapor-deposited coating or layer is directly or indirectly applied to at least a portion of the internal wall of the barrel of a capped pre-assembly comprising a barrel, optionally a dispensing portion, and a cap. The cap is secured to the barrel and at least substantially isolates the distal opening of the dispensing portion from pressure conditions outside the cap. A vapor-deposited coating or layer is applied directly or indirectly to at least a portion of the internal wall of the barrel while the pre-assembly is capped. The coating or layer is applied under conditions effective to maintain communication from the barrel lumen to the exterior via the front opening, optionally further via the dispensing portion lumen if present, at the end of the applying step. The capped pre-assembly can be pressure tested easily and rapidly, for example with a test duration between 1 and 60 seconds, to determine whether it has container closure integrity.

Claims

1. A method comprising:

providing a capped pre-assembly comprising;

a barrel comprising an internal wall defining a barrel lumen and a front opening through the internal wall; and

a cap secured to the barrel and at least substantially isolating the front opening from pressure conditions outside the cap; and

applying a vapor-deposited coating or layer directly or indirectly to at least a portion of the internal wall of the barrel, while the pre-assembly is capped, under conditions effective to maintain communication between the barrel lumen and the exterior via the front opening at the end of the applying step.

2. The invention of claim 1, in which the capped pre-assembly further comprises a dispensing portion secured to the barrel, the dispensing portion comprising a distal opening located outside the barrel, and a dispensing portion lumen communicating between the front opening and the distal opening of the dispensing portion.

3. The invention of claim 1, further comprising, before the providing step, assembling the capped pre-assembly.

4. The invention of claim 3, further comprising, before the assembling step, forming the barrel.

7. The invention of claim 4, in which the barrel is formed by placing a dispensing portion in an injection mold and injection molding the thermoplastic material about the dispensing portion, thus forming the barrel and securing the dispensing portion to the barrel.

11. The invention of claim 2, in which the cap is made of a thermoplastic elastomer.

12. The invention of claim 2, in which the cap of the pre-assembly isolates the distal opening at least partially due to:

contact between the cap and the distal opening,

contact between the cap and the barrel,

or both.

13. The invention of claim 2, in which the cap is sufficiently permeable to a sterilizing gas to sterilize the portions of the assembly isolated by the cap.

17. The invention of claim 2, in which there is substantially no deposition of the vapor-deposited coating or layer in the dispensing portion lumen.

18. The invention of claim 2, in which the barrel further comprises an opening spaced from the dispensing portion and communicating through the internal wall.

19. The invention of claim 18, in which the vapor-deposited coating or layer is applied through the opening.

20. The invention of claim 19, in which the vapor-deposited coating or layer is applied by flowing a reactant vapor material through the opening and employing chemical vapor deposition to deposit a reaction product of the reactant vapor material on the internal wall of the barrel.

40. The invention of claim 2 further comprising, while drawing at least a partial vacuum through the barrel opening, measuring the pressure decay of gas drawn from the barrel opening and any leakage paths.

41. The invention of claim 40, further comprising comparing the pressure decay of gas to a predetermined standard to determine the container closure integrity of the capped pre-assembly.

42. The invention of claim 41, in which the pressure decay is measured with sufficient precision to detect a pressure decay due to an intact container versus a container having a single perforation in the cap having a diameter of 5 microns.

43. The invention of claim 42, in which the pressure decay is measured within a time between 1 second and 60 seconds.

46. The invention of claim 40, in which the pressure decay of gas drawn from the barrel opening and any leakage paths is measured after applying a vapor-deposited coating or layer.

47. The invention of claim 2, in which the vapor-deposited coating or layer is a barrier coating or layer.

63. The invention of claim 2, in which the dispensing portion is a hypodermic needle or a needle-free dispenser.

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64. A prefilled medical syringe or cartridge comprising

a capped pre-assembly comprising:

a barrel comprising an internal wall defining a barrel lumen and a front opening through the internal wall;

a cap secured to the barrel and at least substantially isolating the front opening from pressure conditions outside the cap; and

a dispensing portion secured to the barrel, the dispensing portion comprising a distal opening located outside the barrel, and a dispensing portion lumen communicating between the front opening of the barrel and the distal opening of the dispensing portion;

a piston or plunger tip closing the pre-assembly, and

a material in the barrel lumen selected from the group consisting of any one or more of the following;

Injectable Drugs

Ablavar (Gadofosveset Trisodium Injection)

Abarelix Depot

Abobotulinumtoxin A Injection (Dysport)

ABT-263

ABT-869

ABX-EFG

Accretropin (Somatropin Injection)

Acetadote (Acetylcysteine Injection)

Acetazolamide Injection (Acetazolamide Injection)

Acetylcysteine Injection (Acetadote)

Actemra (Tocilizumab Injection)

Acthrel (Corticorelin Ovine Triflutate for Injection)

Actummune

Activase

Acyclovir for Injection (Zovirax Injection)

Adacel

Adalimumab

Adenoscan (Adenosine Injection)

Adenosine Injection (Adenoscan)

Adrenaclick

AdreView (Iobenguane I 123 Injection for Intravenous Use)

Afluria

Ak-Fluor (Fluorescein Injection)

Aldurazyme (Laronidase)

Alglucerase Injection (Ceredase)

Alkeran Injection (Melphalan Hcl Injection)

Allopurinol Sodium for Injection (Aloprim)

Aloprim (Allopurinol Sodium for Injection)

Alprostadil

Alsuma (Sumatriptan Injection)

ALTU-238

Amino Acid Injections

Aminosyn

Apidra

Apremilast

Alprostadil Dual Chamber System for Injection (Caverject Impulse)

AMG 009

AMG 076

AMG 102

AMG 108

AMG 114

AMG 162

AMG 220

AMG 221

AMG 222

AMG 223

AMG 317

AMG 379

AMG 386

AMG 403

AMG 477

AMG 479

AMG 517

AMG 531

AMG 557

AMG 623

AMG 655

AMG 706

AMG 714

AMG 745

AMG 785

AMG 811

AMG 827

AMG 837

AMG 853

AMG 951

Amiodarone HCl Injection (Amiodarone HCl Injection)

Amobarbital Sodium Injection (Amytal Sodium)

Amytal Sodium (Amobarbital Sodium Injection)

Anakinra

Anti-Abeta

Anti-Beta7

Anti-Beta20

Anti-CD4

Anti-CD20

Anti-CD40

Anti-IFNalpha

Anti-IL13

Anti-OX40L

Anti-oxLDS

Anti-NGF

Anti-NRP1

Arixtra

Amphadase (Hyaluronidase Inj)

Ammonul (Sodium Phenylacetate and Sodium Benzoate Injection)

Anaprox

Anzemet Injection (Dolasetron Mesylate Injection)

Apidra (Insulin Glulisine [rDNA origin] Inj)

Apomab

Aranesp (darbepoetin alfa)

Argatroban (Argatroban Injection)

Arginine Hydrochloride Injection (R-Gene 10

Aristocort

Aristospan

Arsenic Trioxide Injection (Trisenox)

Articane HCl and Epinephrine Injection (Septocaine)

Arzerra (Ofatumumab Injection)

Asclera (Polidocanol Injection)

Ataluren

Ataluren-DMD

Atenolol Inj (Tenormin I.V. Injection)

Atracurium Besylate Injection (Atracurium Besylate Injection)

Avastin

Azactam Injection (Aztreonam Injection)

Azithromycin (Zithromax Injection)

Aztreonam Injection (Azactam Injection)

Baclofen Injection (Lioresal Intrathecal)

Bacteriostatic Water (Bacteriostatic Water for Injection)

Baclofen Injection (Lioresal Intrathecal)

Bal in Oil Ampules (Dimercarprol Injection)

BayHepB

BayTet

Benadryl

Bendamustine Hydrochloride Injection (Treanda)

Benztropine Mesylate Injection (Cogentin)

Betamethasone Injectable Suspension (Celestone Soluspan)

Bexxar

Bicillin C—

R 900/300 (Penicillin G Benzathine and Penicillin G Procaine Injection)

Blenoxane (Bleomycin Sulfate Injection)

Bleomycin Sulfate Injection (Blenoxane)

Boniva Injection (Ibandronate Sodium Injection)

Botox Cosmetic (OnabotulinumtoxinA for Injection)

BR3-FC

Bravelle (Urofollitropin Injection)

Bretylium (Bretylium Tosylate Injection)

Brevital Sodium (Methohexital Sodium for Injection)

Brethine

Briobacept

BTT-1023

Bupivacaine HCl

Byetta

Ca-DTPA (Pentetate Calcium Trisodium Inj)

Cabazitaxel Injection (Jevtana)

Caffeine Alkaloid (Caffeine and Sodium Benzoate Injection)

Calcijex Injection (Calcitrol)

Calcitrol (Calcijex Injection)

Calcium Chloride (Calcium Chloride Injection 10%)

Calcium Disodium Versenate (Edetate Calcium Disodium Injection)

Campath (Altemtuzumab)

Camptosar Injection (Irinotecan Hydrochloride)

Canakinumab Injection (IIaris)

Capastat Sulfate (Capreomycin for Injection)

Capreomycin for Injection (Capastat Sulfate)

Cardiolite (Prep kit for Technetium Tc99 Sestamibi for Injection)

Carticel

Cathflo

Cefazolin and Dextrose for Injection (Cefazolin Injection)

Cefepime Hydrochloride

Cefotaxime

Ceftriaxone

Cerezyme

Carnitor Injection

Caverject

Celestone Soluspan

Celsior

Cerebyx (Fosphenyloin Sodium Injection)

Ceredase (Alglucerase Injection)

Ceretec (Technetium Tc99m Exametazime Injection)

Certolizumab

CF-101

Chloramphenicol Sodium Succinate (Chloramphenicol Sodium Succinate Injection)

Chloramphenicol Sodium Succinate Injection (Chloramphenicol Sodium Succinate)

Cholestagel (Colesevelam HCL)

Choriogonadotropin Alfa Injection (Ovidrel)

Cimzia

Cisplatin (Cisplatin Injection)

Clolar (Clofarabine Injection)

Clomiphine Citrate

Clonidine Injection (Duraclon)

Cogentin (Benztropine Mesylate Injection)

Colistimethate Injection (Coly-Mycin M)

Coly-Mycin M (Colistimethate Injection)

Cornpath

Conivaptan Hcl Injection (Vaprisol)

Conjugated Estrogens for Injection (Premarin Injection)

Copaxone

Corticorelin Ovine Triflutate for Injection (Acthrel)

Corvert (Ibutilide Fumarate Injection)

Cubicin (Daptomycin Injection)

CF-101

Cyanokit (Hydroxocobalamin for Injection)

Cytarabine Liposome Injection (DepoCyt)

Cyanocobalamin

Cytovene (ganciclovir)

D.H.E. 45

Dacetuzumab

Dacogen (Decitabine Injection)

Dalteparin

Dantrium IV (Dantrolene Sodium for Injection)

Dantrolene Sodium for Injection (Dantrium IV)

Daptomycin Injection (Cubicin)

Darbepoietin Alfa

DDAVP Injection (Desmopressin Acetate Injection)

Decavax

Decitabine Injection (Dacogen)

Dehydrated Alcohol (Dehydrated Alcohol Injection)

Denosumab Injection (Prolia)

Delatestryl

Delestrogen

Delteparin Sodium

Depacon (Valproate Sodium Injection)

Depo Medrol (Methylprednisolone Acetate Injectable Suspension)

DepoCyt (Cytarabine Liposome Injection)

DepoDur (Morphine Sulfate XR Liposome Injection)

Desmopressin Acetate Injection (DDAVP Injection)

Depo-Estradiol

Depo-Provera 104 mg/ml

Depo-Provera 150 mg/ml

Depo-Testosterone

Dexrazoxane for Injection, Intravenous Infusion Only (Totect)

Dextrose/Electrolytes

Dextrose and Sodium Chloride lnj (Dextrose 5% in 0.9% Sodium Chloride)

Dextrose

Diazepam Injection (Diazepam Injection)

Digoxin Injection (Lanoxin Injection)

Dilaudid-HP (Hydromorphone Hydrochloride Injection)

Dimercarprol Injection (Bal in Oil Ampules)

Diphenhydramine Injection (Benadryl Injection)

Dipyridamole Injection (Dipyridamole Injection)

DMOAD

Docetaxel for Injection (Taxotere)

Dolasetron Mesylate Injection (Anzemet Injection)

Doribax (Doripenem for Injection)

Doripenem for Injection (Doribax)

Doxercalciferol Injection (Hectorol Injection)

Doxil (Doxorubicin Hcl Liposome Injection)

Doxorubicin Hcl Liposome Injection (Doxil)

Duraclon (Clonidine Injection)

Duramorph (Morphine Injection)

Dysport (Abobotulinumtoxin A Injection)

Ecallantide Injection (Kalbitor)

EC-Naprosyn (naproxen)

Edetate Calcium Disodium Injection (Calcium Disodium Versenate)

Edex (Alprostadil for Injection)

Engerix

Edrophonium Injection (Enlon)

Eliglustat Tartate

Eloxatin (Oxaliplatin Injection)

Emend Injection (Fosaprepitant Dimeglumine Injection)

Enalaprilat Injection (Enalaprilat Injection)

EnIon (Edrophonium Injection)

Enoxaparin Sodium Injection (Lovenox)

Eovist (Gadoxetate Disodium Injection)

Enbrel (etanercept)

Enoxaparin

Epicel

Epinepherine

Epipen

Epipen Jr.

Epratuzumab

Erbitux

Ertapenem Injection (Invanz)

Erythropoieten

Essential Amino Acid Injection (Nephramine)

Estradiol Cypionate

Estradiol Valerate

Etanercept

Exenatide Injection (Byetta)

Evlotra

Fabrazyme (Adalsidase beta)

Famotidine Injection

FDG (Fludeoxyglucose F 18 Injection)

Feraheme (Ferumoxytol Injection)

Feridex I.V. (Ferumoxides Injectable Solution)

Fertinex

Ferumoxides Injectable Solution (Feridex I.V.)

Ferumoxytol Injection (Feraheme)

Flagyl Injection (Metronidazole Injection)

Fluarix

Fludara (Fludarabine Phosphate)

Fludeoxyglucose F 18 Injection (FDG)

Fluorescein Injection (Ak-Fluor)

Follistim AQ Cartridge (Follitropin Beta Injection)

Follitropin Alfa Injection (Gonal-f RFF)

Follitropin Beta Injection (Follistim AQ Cartridge)

Folotyn (Pralatrexate Solution for Intravenous Injection)

Fondaparinux

Forteo (Teriparatide (rDNA origin) Injection)

Fostamatinib

Fosaprepitant Dimeglumine Injection (Emend Injection)

Foscarnet Sodium Injection (Foscavir)

Foscavir (Foscarnet Sodium Injection)

Fosphenyloin Sodium Injection (Cerebyx)

Fospropofol Disodium Injection (Lusedra)

Fragmin

Fuzeon (enfuvirtide)

GA101

Gadobenate Dimeglumine Injection (Multihance)

Gadofosveset Trisodium Injection (Ablavar)

Gadoteridol Injection Solution (ProHance)

Gadoversetamide Injection (OptiMARK)

Gadoxetate Disodium Injection (Eovist)

Ganirelix (Ganirelix Acetate Injection)

Gardasil

GC1008

GDFD

Gemtuzumab Ozogamicin for Injection (Mylotarg)

Genotropin

Gentamicin Injection

GENZ-112638

Golimumab Injection (Simponi Injection)

Gonal-f RFF (Follitropin Alfa Injection)

Granisetron Hydrochloride (Kytril Injection)

Gentamicin Sulfate

Glatiramer Acetate

Glucagen

Glucagon

HAE1

Haldol (Haloperidol Injection)

Havrix

Hectorol Injection (Doxercalciferol Injection)

Hedgehog Pathway Inhibitor

Heparin

Herceptin

hG-CSF

Humalog

Human Growth Hormone

Humatrope

HuMax

Humegon

Hurnira

Humulin

Ibandronate Sodium Injection (Boniva Injection)

Ibuprofen Lysine Injection (NeoProfen)

Ibutilide Fumarate Injection (Corvert)

Idamycin PFS (Idarubicin Hydrochloride Injection)

Idarubicin Hydrochloride Injection (Idamycin PFS)

Ilaris (Canakinumab Injection)

Imipenem and Cilastatin for Injection (Primaxin I.V.)

Imitrex

Incobotulinumtoxin A for Injection (Xeomin)

Increlex (Mecasermin [rDNA origin] Injection)

Indocin IV (Indomethacin Inj)

Indomethacin Inj (Indocin IV)

Infanrix

Innohep

Insulin

Insulin Aspart [rDNA origin] lnj (NovoLog)

Insulin Glargine [rDNA origin] Injection (Lantus)

Insulin Glulisine [rDNA origin] Inj (Apidra)

Interferon alfa-2b, Recombinant for Injection (Intron A)

Intron A (Interferon alfa-2b, Recombinant for Injection)

Invanz (Ertapenem Injection)

Invega Sustenna (Paliperidone Palmitate Extended-Release Injectable Suspension)

Invirase (saquinavir mesylate)

Iobenguane I 123 Injection for Intravenous Use (AdreView)

Iopromide Injection (Ultravist)

Ioversol Injection (Optiray Injection)

Iplex (Mecasermin Rinfabate [rDNA origin] Injection)

Iprivask

Irinotecan Hydrochloride (Camptosar Injection)

Iron Sucrose Injection (Venofer)

Istodax (Romidepsin for Injection)

Itraconazole Injection (Sporanox Injection)

Jevtana (Cabazitaxel Injection)

Jonexa

Kalbitor (Ecallantide Injection)

KCL in D5NS (Potassium Chloride in 5% Dextrose and Sodium Chloride Injection)

KCL in D5W

KCL in NS

Kenalog 10 Injection (Triamcinolone Acetonide Injectable Suspension)

Kepivance (Palifermin)

Keppra Injection (Levetiracetam)

Keratinocyte

KFG

Kinase Inhibitor

Kineret (Anakinra)

Kinlytic (Urokinase Injection)

Kin rix

Klonopin (clonazepam)

Kytril Injection (Granisetron Hydrochloride)

lacosamide Tablet and Injection (Vimpat)

Lactated Ringer'"'"'s

Lanoxin Injection (Digoxin Injection)

Lansoprazole for Injection (Prevacid I.V.)

Lantus

Leucovorin Calcium (Leucovorin Calcium Injection)

Lente (L)

Leptin

Levemir

Leukine Sargramostim

Leuprolide Acetate

Levothyroxine

Levetiracetam (Keppra Injection)

Lovenox

Levocarnitine Injection (Carnitor Injection)

Lexiscan (Regadenoson Injection)

Lioresal Intrathecal (Baclofen Injection)

Liraglutide [rDNA] Injection (Victoza)

Lovenox (Enoxaparin Sodium Injection)

Lucentis (Ranibizumab Injection)

Lumizyme

Lupron (Leuprolide Acetate Injection)

Lusedra (Fospropofol Disodium Injection)

Maci

Magnesium Sulfate (Magnesium Sulfate Injection)

Mannitol Injection (Mannitol IV)

Marcaine (Bupivacaine Hydrochloride and Epinephrine Injection)

Maxipime (Cefepime Hydrochloride for Injection)

MDP Multidose Kit of Technetium Injection (Technetium Tc99m Medronate Injection)

Mecasermin [rDNA origin] Injection (Increlex)

Mecasermin Rinfabate [rDNA origin] Injection (lplex)

Melphalan Hcl Injection (Alkeran Injection)

Methotrexate

Menactra

Menopur (Menotropins Injection)

Menotropins for Injection (Repronex)

Methohexital Sodium for Injection (Brevital Sodium)

Methyldopate Hydrochloride Injection, Solution (Methyldopate Hcl)

Methylene Blue (Methylene Blue Injection)

Methylprednisolone Acetate Injectable Suspension (Depo Medrol)

MetMab

Metoclopramide Injection (Reglan Injection)

Metrodin (Urofollitropin for Injection)

Metronidazole Injection (Flagyl Injection)

Miacalcin

Midazolam (Midazolam Injection)

Mimpara (Cinacalet)

Minocin Injection (Minocycline Inj)

Minocycline Inj (Minocin Injection)

Mipomersen

Mitoxantrone for Injection Concentrate (Novantrone)

Morphine Injection (Duramorph)

Morphine Sulfate XR Liposome Injection (DepoDur)

Morrhuate Sodium (Morrhuate Sodium Injection)

Motesanib

Mozobil (Plerixafor Injection)

Multihance (Gadobenate Dimeglumine Injection)

Multiple Electrolytes and Dextrose Injection

Multiple Electrolytes Injection

Mylotarg (Gemtuzumab Ozogamicin for Injection)

Myozyme (Alglucosidase alfa)

Nafcillin Injection (Nafcillin Sodium)

Nafcillin Sodium (Nafcillin Injection)

Naltrexone XR Inj (Vivitrol)

Naprosyn (naproxen)

NeoProfen (Ibuprofen Lysine Injection)

Nandrol Decanoate

Neostigmine Methylsulfate (Neostigmine Methylsulfate Injection)

NEO-GAA

NeoTect (Technetium Tc 99m Depreotide Injection)

Nephramine (Essential Amino Acid Injection)

Neulasta (pegfilgrastim)

Neupogen (Filgrastim)

Novolin

Novolog

NeoRecormon

Neutrexin (Trimetrexate Glucuronate Inj)

NPH(N)

Nexterone (Amiodarone HCl Injection)

Norditropin (Somatropin Injection)

Normal Saline (Sodium Chloride Injection)

Novantrone (Mitoxantrone for Injection Concentrate)

Novolin 70/30 Innolet (70% NPH, Human Insulin Isophane Suspension and 30%

Regular, Human Insulin Injection)

NovoLog (Insulin Aspart [rDNA origin] Inj)

Nplate (romiplostim)

Nutropin (Somatropin (rDNA origin) for Inj)

Nutropin AQ

Nutropin Depot (Somatropin (rDNA origin) for Inj)

Octreotide Acetate Injection (Sandostatin LAR)

Ocrelizumab

Ofatumumab Injection (Arzerra)

Olanzapine Extended Release Injectable Suspension (Zyprexa Relprevv)

Omnitarg

Omnitrope (Somatropin [rDNA origin] Injection)

Ondansetron Hydrochloride Injection (Zofran Injection)

OptiMARK (Gadoversetamide Injection)

Optiray Injection (loversol Injection)

Orencia

Osmitrol Injection in Aviva (Mannitol Injection in Aviva Plastic Vessel

     250)

Osmitrol Injection in Viaflex (Mannitol Injection in Viaflex Plastic Vessel

     250)

Osteoprotegrin

Ovidrel (Choriogonadotropin Alfa Injection)

Oxacillin (Oxacillin for Injection)

Oxaliplatin Injection (Eloxatin)

Oxytocin Injection (Pitocin)

Paliperidone Palmitate Extended-Release Injectable Suspension (Invega Sustenna)

Pamidronate Disodium Injection (Pamidronate Disodium Injection)

Panitumumab Injection for Intravenous Use (Vectibix)

Papaverine Hydrochloride Injection (Papaverine Injection)

Papaverine Injection (Papaverine Hydrochloride Injection)

Parathyroid Hormone

Paricalcitol Injection Fliptop Vial (Zemplar Injection)

PARP Inhibitor

Pediarix

PEGIntron

Peginterferon

Pegfilgrastim

Penicillin G Benzathine and Penicillin G Procaine

Pentetate Calcium Trisodium Inj (Ca-DTPA)

Pentetate Zinc Trisodium Injection (Zn-DTPA)

Pepcid Injection (Famotidine Injection)

Pergonal

Pertuzumab

Phentolamine Mesylate (Phentolamine Mesylate for Injection)

Physostigmine Salicylate (Physostigmine Salicylate (injection))

Physostigmine Salicylate (injection) (Physostigmine Salicylate)

Piperacillin and Tazobactam Injection (Zosyn)

Pitocin (Oxytocin Injection)

Plasma-Lyte 148 (Multiple Electrolytes Inj)

Plasma-Lyte 56 and Dextrose (Multiple Electrolytes and Dextrose Injection in Viaflex

Plastic Vessel

     250)

PlasmaLyte

Plerixafor Injection (Mozobil)

Polidocanol Injection (Asclera)

Potassium Chloride

Pralatrexate Solution for Intravenous Injection (Folotyn)

Pramlintide Acetate Injection (Symlin)

Premarin Injection (Conjugated Estrogens for Injection)

Prep kit for Technetium Tc99 Sestamibi for Injection (Cardiolite)

Prevacid I.V. (Lansoprazole for Injection)

Primaxin I.V. (Imipenem and Cilastatin for Injection)

Prochymal

Procrit

Progesterone

ProHance (Gadoteridol Injection Solution)

Prolia (Denosumab Injection)

Promethazine HCl Injection (Promethazine Hydrochloride Injection)

Propranolol Hydrochloride Injection (Propranolol Hydrochloride Injection)

Quinidine Gluconate Injection (Quinidine Injection)

Quinidine Injection (Quinidine Gluconate Injection)

R-Gene 10 (Arginine Hydrochloride Injection)

Ranibizumab Injection (Lucentis)

Ranitidine Hydrochloride Injection (Zantac Injection)

Raptiva

Reclast (Zoledronic Acid Injection)

Recombivarix HB

Regadenoson Injection (Lexiscan)

Reglan Injection (Metoclopramide Injection)

Remicade

Renagel

Renvela (Sevelamer Carbonate)

Repronex (Menotropins for Injection)

Retrovir IV (Zidovudine Injection)

rhApo2L/TRAIL

Ringer'"'"'s and 5% Dextrose Injection (Ringers in Dextrose)

Ringer'"'"'s Injection (Ringers Injection)

Rituxan

Rituximab

Rocephin (ceftriaxone)

Rocuronium Bromide Injection (Zemuron)

Roferon-A (interferon alfa-3)

Romazicon (flumazenil)

Romidepsin for Injection (Istodax)

Saizen (Somatropin Injection)

Sandostatin LAR (Octreotide Acetate Injection)

Sclerostin Ab

Sensipar (cinacalcet)

Sensorcaine (Bupivacaine HCl Injections)

Septocaine (Articane HCl and Epinephrine Injection)

Serostim LQ (Somatropin (rDNA origin) Injection)

Simponi Injection (Golimumab Injection)

Sodium Acetate (Sodium Acetate Injection)

Sodium Bicarbonate (Sodium Bicarbonate 5% Injection)

Sodium Lactate (Sodium Lactate Injection in AVIVA)

Sodium Phenylacetate and Sodium Benzoate Injection (Ammonul)

Somatropin (rDNA origin) for Inj (Nutropin)

Sporanox Injection (Itraconazole Injection)

Stelara Injection (Ustekinumab)

Stemgen

Sufenta (Sufentanil Citrate Injection)

Sufentanil Citrate Injection (Sufenta)

Sumavel

Sumatriptan Injection (Alsuma)

Symlin

Symlin Pen

Systemic Hedgehog Antagonist

Synvisc-One (Hylan G-F 20 Single Intra-articular Injection)

Tarceva

Taxotere (Docetaxel for Injection)

Technetium Tc 99m

Telavancin for Injection (Vibativ)

Temsirolimus Injection (Torisel)

Tenormin I.V. Injection (Atenolol Inj)

Teriparatide (rDNA origin) Injection (Forteo)

Testosterone Cypionate

Testosterone Enanthate

Testosterone Propionate

Tev-Tropin (Somatropin, rDNA Origin, for Injection)

tgAAC94

Thallous Chloride

Theophylline

Thiotepa (Thiotepa Injection)

Thymoglobulin (Anti-Thymocyte Globulin (Rabbit)

Thyrogen (Thyrotropin Alfa for Injection)

Ticarcillin Disodium and Clavulanate Potassium Galaxy (Timentin Injection)

Tigan Injection (Trimethobenzamide Hydrochloride Injectable)

Timentin Injection (Ticarcillin Disodium and Clavulanate Potassium Galaxy)

TNKase

Tobramycin Injection (Tobramycin Injection)

Tocilizumab Injection (Actemra)

Torisel (Temsirolimus Injection)

Totect (Dexrazoxane for Injection, Intravenous Infusion Only)

Trastuzumab-DM1

Travasol (Amino Acids (Injection))

Treanda (Bendamustine Hydrochloride Injection)

Trelstar (Triptorelin Pamoate for Injectable Suspension)

Triamcinolone Acetonide

Triamcinolone Diacetate

Triamcinolone Hexacetonide Injectable Suspension (Aristospan Injection 20 mg)

Triesence (Triamcinolone Acetonide Injectable Suspension)

Trimethobenzamide Hydrochloride Injectable (Tigan Injection)

Trimetrexate Glucuronate Inj (Neutrexin)

Triptorelin Pamoate for Injectable Suspension (Trelstar)

Twinject

Trivaris (Triamcinolone Acetonide Injectable Suspension)

Trisenox (Arsenic Trioxide Injection)

Twinrix

Typhoid Vi

Ultravist (lopromide Injection)

Urofollitropin for Injection (Metrodin)

Urokinase Injection (Kinlytic)

Ustekinumab (Stelara Injection)

Ultralente (U)

Valium (diazepam)

Valproate Sodium Injection (Depacon)

Valtropin (Somatropin Injection)

Vancomycin Hydrochloride (Vancomycin Hydrochloride Injection)

Vancomycin Hydrochloride Injection (Vancomycin Hydrochloride)

Vaprisol (Conivaptan Hcl Injection)

VAQTA

Vasovist (Gadofosveset Trisodium Injection for Intravenous Use)

Vectibix (Panitumumab Injection for Intravenous Use)

Venofer (Iron Sucrose Injection)

Verteporfin Inj (Visudyne)

Vibativ (Telavancin for Injection)

Victoza (Liraglutide [rDNA] Injection)

Vimpat (lacosamide Tablet and Injection)

Vinblastine Sulfate (Vinblastine Sulfate Injection)

Vincasar PFS (Vincristine Sulfate Injection)

Victoza

Vincristine Sulfate (Vincristine Sulfate Injection)

Visudyne (Verteporfin Inj)

Vitamin B-12

Vivitrol (Naltrexone XR Inj)

Voluven (Hydroxyethyl Starch in Sodium Chloride Injection)

Xeloda

Xenical (orlistat)

Xeomin (Incobotulinumtoxin A for Injection)

Xolair

Zantac Injection (Ranitidine Hydrochloride Injection)

Zemplar Injection (Paricalcitol Injection Fliptop Vial)

Zemuron (Rocuronium Bromide Injection)

Zenapax (daclizumab)

Zevalin

Zidovudine Injection (Retrovir IV)

Zithromax Injection (Azithromycin)

Zn-DTPA (Pentetate Zinc Trisodium Injection)

Zofran Injection (Ondansetron Hydrochloride Injection)

Zingo

Zoledronic Acid for Inj (Zometa)

Zoledronic Acid Injection (Reclast)

Zometa (Zoledronic Acid for Inj)

Zosyn (Piperacillin and Tazobactam Injection)

Zyprexa Relprevv (Olanzapine Extended Release Injectable Suspension)

Liquid Drugs (Non-Injectable)

Abilify

AccuNeb (Albuterol Sulfate Inhalation Solution)

Actidose Aqua (Activated Charcoal Suspension)

Activated Charcoal Suspension (Actidose Aqua)

Advair

Agenerase Oral Solution (Amprenavir Oral Solution)

Akten (Lidocaine Hydrochloride Ophthalmic Gel)

Alamast (Pemirolast Potassium Ophthalmic Solution)

Albumin (Human) 5% Solution (Buminate 5%)

Albuterol Sulfate Inhalation Solution

Alinia

Alocril

Alphagan

Alrex

Alvesco

Amprenavir Oral Solution

Analpram-HC

Arformoterol Tartrate Inhalation Solution (Brovana)

Aristospan Injection 20 mg (Triamcinolone Hexacetonide Injectable Suspension)

Asacol

Asmanex

Astepro

Astepro (Azelastine Hydrochloride Nasal Spray)

Atrovent Nasal Spray (Ipratropium Bromide Nasal Spray)

Atrovent Nasal Spray 0.06

Augmentin ES-600

Azasite (Azithromycin Ophthalmic Solution)

Azelaic Acid (Finacea Gel)

Azelastine Hydrochloride Nasal Spray (Astepro)

Azelex (Azelaic Acid Cream)

Azopt (Brinzolamide Ophthalmic Suspension)

Bacteriostatic Saline

Balanced Salt

Bepotastine

Bactroban Nasal

Bactroban

Beclovent

Benzac W

Betimol

Betoptic S

Bepreve

Bimatoprost Ophthalmic Solution

Bleph 10 (Sulfacetamide Sodium Ophthalmic Solution 10%)

Brinzolamide Ophthalmic Suspension (Azopt)

Bromfenac Ophthalmic Solution (Xibrom)

Bromhist

Brovana (Arformoterol Tartrate Inhalation Solution)

Budesonide Inhalation Suspension (Pulmicort Respules)

Cambia (Diclofenac Potassium for Oral Solution)

Capex

Carac

Carboxine-PSE

Carnitor

Cayston (Aztreonam for Inhalation Solution)

Cellcept

Centany

Cerumenex

Ciloxan Ophthalmic Solution (Ciprofloxacin HCL Ophthalmic Solution)

Ciprodex

Ciprofloxacin HCL Ophthalmic Solution (Ciloxan Ophthalmic Solution)

Clemastine Fumarate Syrup (Clemastine Fumarate Syrup)

CoLyte (PEG Electrolytes Solution)

Combiven

Comtan

Condylox

Cordran

Cortisporin Ophthalmic Suspension

Cortisporin Otic Suspension

Cromolyn Sodium Inhalation Solution (Intal Nebulizer Solution)

Cromolyn Sodium Ophthalmic Solution (Opticrom)

Crystalline Amino Acid Solution with Electrolytes (Aminosyn Electrolytes)

Cutivate

Cuvposa (Glycopyrrolate Oral Solution)

Cyanocobalamin (CaloMist Nasal Spray)

Cyclosporine Oral Solution (Gengraf Oral Solution)

Cyclogyl

Cysview (Hexamino)evulinate Hydrochloride Intravesical Solution)

DermOtic Oil (Fluocinolone Acetonide Oil Ear Drops)

Desmopressin Acetate Nasal Spray

DDAVP

Derma-Smoothe/FS

Dexamethasone Intensol

Dianeal Low Calcium

Dianeal PD

Diclofenac Potassium for Oral Solution (Cambia)

Didanosine Pediatric Powder for Oral Solution (Videx)

Differin

Dilantin 125 (Phenyloin Oral Suspension)

Ditropan

Dorzolamide Hydrochloride Ophthalmic Solution (Trusopt)

Dorzolamide Hydrochloride-Timolol Maleate Ophthalmic Solution (Cosopt)

Dovonex Scalp (Calcipotriene Solution)

Doxycycline Calcium Oral Suspension (Vibramycin Oral)

Efudex

Elaprase (Idursulfase Solution)

Elestat (Epinastine HCl Ophthalmic Solution)

Elocon

Epinastine HCl Ophthalmic Solution (Elestat)

Epivir HBV

Epogen (Epoetin alfa)

Erythromycin Topical Solution 1.5% (Staticin)

Ethiodol (Ethiodized Oil)

Ethosuximide Oral Solution (Zarontin Oral Solution)

Eurax

Extraneal (Icodextrin Peritoneal Dialysis Solution)

Felbatol

Feridex I.V. (Ferumoxides Injectable Solution)

Flovent

Floxin Otic (Ofloxacin Otic Solution)

Flo-Pred (Prednisolone Acetate Oral Suspension)

Fluoroplex

Flunisolide Nasal Solution (Flunisolide Nasal Spray 0.025%)

Fluorometholone Ophthalmic Suspension (FML)

Flurbiprofen Sodium Ophthalmic Solution (Ocufen)

FML

Foradil

Formoterol Fumarate Inhalation Solution (Perforomist)

Fosamax

Furadantin (Nitrofurantoin Oral Suspension)

Furoxone

Gammagard Liquid (Immune Globulin Intravenous (Human) 10%)

Gantrisin (Acetyl Sulfisoxazole Pediatric Suspension)

Gatifloxacin Ophthalmic Solution (Zymar)

Gengraf Oral Solution (Cyclosporine Oral Solution)

Glycopyrrolate Oral Solution (Cuvposa)

Halcinonide Topical Solution (Halog Solution)

Halog Solution (Halcinonide Topical Solution)

HEP-LOCK U/P (Preservative-Free Heparin Lock Flush Solution)

Heparin Lock Flush Solution (Hepflush 10

Hexaminolevulinate Hydrochloride Intravesical Solution (Cysview)

Hydrocodone Bitartrate and Acetaminophen Oral Solution (Lortab Elixir)

Hydroquinone 3% Topical Solution (Melquin-3 Topical Solution)

IAP Antagonist

Isopto

Ipratropium Bromide Nasal Spray (Atrovent Nasal Spray)

Itraconazole Oral Solution (Sporanox Oral Solution)

Ketorolac Tromethamine Ophthalmic Solution (Acular LS)

Kaletra

Lanoxin

Lexiva

Leuprolide Acetate for Depot Suspension (Lupron Depot 11.25 mg)

Levobetaxolol Hydrochloride Ophthalmic Suspension (Betaxon)

Levocarnitine Tablets, Oral Solution, Sugar-Free (Carnitor)

Levofloxacin Ophthalmic Solution 0.5% (Quixin)

Lidocaine HCl Sterile Solution (Xylocalne MPF Sterile Solution)

Lok Pak (Heparin Lock Flush Solution)

Lorazepam Intensol

Lortab Elixir (Hydrocodone Bitartrate and Acetaminophen Oral Solution)

Lotemax (Loteprednol Etabonate Ophthalmic Suspension)

Loteprednol Etabonate Ophthalmic Suspension (Alrex)

Low Calcium Peritoneal Dialysis Solutions (Dianeal Low Calcium)

Lumigan (Bimatoprost Ophthalmic Solution 0.03% for Glaucoma)

Lupron Depot 11.25 mg (Leuprolide Acetate for Depot Suspension)

Megestrol Acetate Oral Suspension (Megestrol Acetate Oral Suspension)

MEK Inhibitor

Mepron

Mesnex

Mestinon

Mesalamine Rectal Suspension Enema (Rowasa)

Melquin-3 Topical Solution (Hydroquinone 3% Topical Solution)

MetMab

Methyldopate Hcl (Methyldopate Hydrochloride Injection, Solution)

Methylin Oral Solution (Methylphenidate HCl Oral Solution 5 mg/5 mL and 10 mg/5 mL)

Methylprednisolone Acetate Injectable Suspension (Depo Medrol)

Methylphenidate HCl Oral Solution 5 mg/5 mL and 10 mg/5 mL (Methylin Oral Solution)

Methylprednisolone sodium succinate (Solu Medrol)

Metipranolol Ophthalmic Solution (Optipranolol)

Migranal

Miochol-E (Acetylcholine Chloride Intraocular Solution)

Micro-K for Liquid Suspension (Potassium Chloride Extended Release Formulation for

Liquid Suspension)

Minocin (Minocycline Hydrochloride Oral Suspension)

Nasacort

Neomycin and Polymyxin B Sulfates and Hydrocortisone

Nepafenac Ophthalmic Suspension (Nevanac)

Nevanac (Nepafenac Ophthalmic Suspension)

Nitrofurantoin Oral Suspension (Furadantin)

Noxafil (Posaconazole Oral Suspension)

Nystatin (oral) (Nystatin Oral Suspension)

Nystatin Oral Suspension (Nystatin (oral))

Ocufen (Flurbiprofen Sodium Ophthalmic Solution)

Ofloxacin Ophthalmic Solution (Ofloxacin Ophthalmic Solution)

Ofloxacin Otic Solution (Floxin Otic)

Olopatadine Hydrochloride Ophthalmic Solution (Pataday)

Opticrom (Cromolyn Sodium Ophthalmic Solution)

Optipranolol (Metipranolol Ophthalmic Solution)

Patanol

Pediapred

PerioGard

Phenyloin Oral Suspension (Dilantin

     125)

Phisohex

Posaconazole Oral Suspension (Noxafil)

Potassium Chloride Extended Release Formulation for Liquid Suspension (Micro-K for

Liquid Suspension)

Pataday (Olopatadine Hydrochloride Ophthalmic Solution)

Patanase Nasal Spray (Olopatadine Hydrochloride Nasal Spray)

PEG Electrolytes Solution (CoLyte)

Pemirolast Potassium Ophthalmic Solution (Alamast)

Penlac (C_1-clopirox Topical Solution)

PENNSAID (Diclofenac Sodium Topical Solution)

Perforomist (Formoterol Fumarate Inhalation Solution)

Peritoneal Dialysis Solution

Phenylephrine Hydrochloride Ophthalmic Solution (Neo-Synephrine)

Phospholine Iodide (Echothiophate Iodide for Ophthalmic Solution)

Podofilox (Podofilox Topical Solution)

Pred Forte (Prednisolone Acetate Ophthalmic Suspension)

Pralatrexate Solution for Intravenous Injection (Folotyn)

Pred Mild

Prednisone Intensol

Prednisolone Acetate Ophthalmic Suspension (Pred Forte)

Prevacid

PrismaSol Solution (Sterile Hemofiltration Hemodiafiltration Solution)

ProAir

Proglycem

ProHance (Gadoteridol Injection Solution)

Proparacaine Hydrochloride Ophthalmic Solution (Alcaine)

Propine

Pulmicort

Pulmozyme

Quixin (Levofloxacin Ophthalmic Solution 0.5%)

QVAR

Rapamune

Rebetol

Relacon-HC

Rotarix (Rotavirus Vaccine, Live, Oral Suspension)

Rotavirus Vaccine, Live, Oral Suspension (Rotarix)

Rowasa (Mesalamine Rectal Suspension Enema)

Sabril (Vigabatrin Oral Solution)

Sacrosidase Oral Solution (Sucraid)

Sandimmune

Sepra

Serevent Diskus

Solu Cortef (Hydrocortisone Sodium Succinate)

Solu Medrol (Methylprednisolone sodium succinate)

Spiriva

Sporanox Oral Solution (Itraconazole Oral Solution)

Staticin (Erythromycin Topical Solution 1.5%)

Stalevo

Starlix

Sterile Hemofiltration Hemodiafiltration Solution (PrismaSol Solution)

Stimate

Sucralfate (Carafate Suspension)

Sulfacetamide Sodium Ophthalmic Solution 10% (Bleph 10

Synarel Nasal Solution (Nafarelin Acetate Nasal Solution for Endometriosis)

Taclonex Scalp (Calcipotriene and Betamethasone Dipropionate Topical Suspension)

Tamiflu

Tobi

TobraDex

Tobradex ST (Tobramycin/Dexamethasone Ophthalmic Suspension 0.3%/0.05%)

Tobramycin/Dexamethasone Ophthalmic Suspension 0.3%/0.05% (Tobradex ST)

Timolol

Timoptic

Travatan Z

Treprostinil Inhalation Solution (Tyvaso)

Trusopt (Dorzolamide Hydrochloride Ophthalmic Solution)

Tyvaso (Treprostinil Inhalation Solution)

Ventolin

Vfend

Vibramycin Oral (Doxycycline Calcium Oral Suspension)

Videx (Didanosine Pediatric Powder for Oral Solution)

Vigabatrin Oral Solution (Sabril)

Viokase

Viracept

Viramune

Vitamin K1 (Fluid Colloidal Solution of Vitamin K1)

Voltaren Ophthalmic (Diclofenac Sodium Ophthalmic Solution)

Zarontin Oral Solution (Ethosuximide Oral Solution)

Ziagen

Zyvox

Zymar (Gatifloxacin Ophthalmic Solution)

Zymaxid (Gatifloxacin Ophthalmic Solution)

Drug Classes

5-alpha-reductase inhibitors

5-aminosalicylates

5HT3 receptor antagonists

adamantane antivirals

adrenal cortical steroids

adrenal corticosteroid inhibitors

adrenergic bronchodilators

agents for hypertensive emergencies

agents for pulmonary hypertension

aldosterone receptor antagonists

alkylating agents

alpha-adrenoreceptor antagonists

alpha-glucosidase inhibitors

alternative medicines

amebicides

aminoglycosides

aminopenicillins

aminosalicylates

amylin analogs

Analgesic Combinations

Analgesics

androgens and anabolic steroids

angiotensin converting enzyme inhibitors

angiotensin II inhibitors

anorectal preparations

anorexiants

antacids

anthelmintics

anti-angiogenic ophthalmic agents

anti-CTLA-4 monoclonal antibodies

anti-infectives

antiadrenergic agents, centrally acting

antiadrenergic agents, peripherally acting

antiandrogens

antianginal agents

antiarrhythmic agents

antiasthmatic combinations

antibiotics/antineoplastics

anticholinergic antiemetics

anticholinergic antiparkinson agents

anticholinergic bronchodilators

anticholinergic chronotropic agents

anticholinergics/antispasmodics

anticoagulants

anticonvulsants

antidepressants

antidiabetic agents

antidiabetic combinations

antidiarrheals

antidiuretic hormones

antidotes

antiemetic/antivertigo agents

antifungals

antigonadotropic agents

antigout agents

antihistamines

antihyperlipidemic agents

antihyperlipidemic combinations

antihypertensive combinations

antihyperuricemic agents

antimalarial agents

antimalarial combinations

antimalarial quinolines

antimetabolites

antimigraine agents

antineoplastic detoxifying agents

antineoplastic interferons

antineoplastic monoclonal antibodies

antineoplastics

antiparkinson agents

antiplatelet agents

antipseudomonal penicillins

antipsoriatics

antipsychotics

antirheumatics

antiseptic and germicides

antithyroid agents

antitoxins and antivenins

antituberculosis agents

antituberculosis combinations

antitussives

antiviral agents

antiviral combinations

antiviral interferons

anxiolytics, sedatives, and hypnotics

aromatase inhibitors

atypical antipsychotics

azole antifungals

bacterial vaccines

barbiturate anticonvulsants

barbiturates

BCR-ABL tyrosine kinase inhibitors

benzodiazepine anticonvulsants

benzodiazepines

beta-adrenergic blocking agents

beta-lactamase inhibitors

bile acid sequestrants

biologicals

bisphosphonates

bone resorption inhibitors

bronchodilator combinations

bronchodilators

calcitonin

calcium channel blocking agents

carbamate anticonvulsants

carbapenems

carbonic anhydrase inhibitor anticonvulsants

carbonic anhydrase inhibitors

cardiac stressing agents

cardioselective beta blockers

cardiovascular agents

catecholamines

CD₂O monoclonal antibodies

CD33 monoclonal antibodies

CD52 monoclonal antibodies

central nervous system agents

cephalosporins

cerumenolytics

chelating agents

chemokine receptor antagonist

chloride channel activators

cholesterol absorption inhibitors

cholinergic agonists

cholinergic muscle stimulants

cholinesterase inhibitors

CNS stimulants

coagulation modifiers

colony stimulating factors

contraceptives

corticotropin

coumarins and indandiones

cox-2 inhibitors

decongestants

dermatological agents

diagnostic radiopharmaceuticals

dibenzazepine anticonvulsants

digestive enzymes

dipeptidyl peptidase 4 inhibitors

diuretics

dopaminergic antiparkinsonism agents

drugs used in alcohol dependence

echinocandins

EGFR inhibitors

estrogen receptor antagonists

estrogens

expectorants

factor Xa inhibitors

fatty acid derivative anticonvulsants

fibric acid derivatives

first generation cephalosporins

fourth generation cephalosporins

functional bowel disorder agents

gallstone solubilizing agents

gamma-aminobutyric acid analogs

gamma-aminobutyric acid reuptake inhibitors

gamma-aminobutyric acid transaminase inhibitors

gastrointestinal agents

general anesthetics

genitourinary tract agents

GI stimulants

glucocorticoids

glucose elevating agents

glycopeptide antibiotics

glycoprotein platelet inhibitors

glycylcyclines

gonadotropin releasing hormones

gonadotropin-releasing hormone antagonists

gonadotropins

group I antiarrhythmics

group II antiarrhythmics

group III antiarrhythmics

group IV antiarrhythmics

group V antiarrhythmics

growth hormone receptor blockers

growth hormones

H. pylori eradication agents

H2 antagonists

hematopoietic stem cell mobilizer

heparin antagonists

heparins

HER2 inhibitors

herbal products

histone deacetylase inhibitors

hormone replacement therapy

hormones

hormones/antineoplastics

hydantoin anticonvulsants

illicit (street) drugs

immune globulins

immunologic agents

immunosuppressive agents

impotence agents

in vivo diagnostic biologicals

incretin mimetics

inhaled anti-infectives

inhaled corticosteroids

inotropic agents

insulin

insulin-like growth factor

integrase strand transfer inhibitor

interferons

intravenous nutritional products

iodinated contrast media

ionic iodinated contrast media

iron products

ketolides

laxatives

leprostatics

leukotriene modifiers

lincomycin derivatives

lipoglycopeptides

local injectable anesthetics

loop diuretics

lung surfactants

lymphatic staining agents

lysosomal enzymes

macrolide derivatives

macrolides

magnetic resonance imaging contrast media

mast cell stabilizers

medical gas

meglitinides

metabolic agents

methylxanthines

mineralocorticoids

minerals and electrolytes

miscellaneous agents

miscellaneous analgesics

miscellaneous antibiotics

miscellaneous anticonvulsants

miscellaneous antidepressants

miscellaneous antidiabetic agents

miscellaneous antiemetics

miscellaneous antifungals

miscellaneous antihyperlipidemic agents

miscellaneous antimalarials

miscellaneous antineoplastics

miscellaneous antiparkinson agents

miscellaneous antipsychotic agents

miscellaneous antituberculosis agents

miscellaneous antivirals

miscellaneous anxiolytics, sedatives and hypnotics

miscellaneous biologicals

miscellaneous bone resorption inhibitors

miscellaneous cardiovascular agents

miscellaneous central nervous system agents

miscellaneous coagulation modifiers

miscellaneous diuretics

miscellaneous genitourinary tract agents

miscellaneous GI agents

miscellaneous hormones

miscellaneous metabolic agents

miscellaneous ophthalmic agents

miscellaneous otic agents

miscellaneous respiratory agents

miscellaneous sex hormones

miscellaneous topical agents

miscellaneous uncategorized agents

miscellaneous vaginal agents

mitotic inhibitors

monoamine oxidase inhibitors

monoclonal antibodies

mouth and throat products

mTOR inhibitors

mTOR kinase inhibitors

mucolytics

multikinase inhibitors

muscle relaxants

mydriatics

narcotic analgesic combinations

narcotic analgesics

nasal anti-infectives

nasal antihistamines and decongestants

nasal lubricants and irrigations

nasal preparations

nasal steroids

natural penicillins

neuraminidase inhibitors

neuromuscular blocking agents

next generation cephalosporins

nicotinic acid derivatives

nitrates

NNRTIs

non-cardioselective beta blockers

non-iodinated contrast media

non-ionic iodinated contrast media

non-sulfonylureas

nonsteroidal anti-inflammatory agents

norepinephrine reuptake inhibitors

norepinephrine-dopamine reuptake inhibitors

nucleoside reverse transcriptase inhibitors (NRTIs)

nutraceutical products

nutritional products

ophthalmic anesthetics

ophthalmic anti-infectives

ophthalmic anti-inflammatory agents

ophthalmic antihistamines and decongestants

ophthalmic diagnostic agents

ophthalmic glaucoma agents

ophthalmic lubricants and irrigations

ophthalmic preparations

ophthalmic steroids

ophthalmic steroids with anti-infectives

ophthalmic surgical agents

oral nutritional supplements

otic anesthetics

otic anti-infectives

otic preparations

otic steroids

otic steroids with anti-infectives

oxazolidinedione anticonvulsants

parathyroid hormone and analogs

penicillinase resistant penicillins

penicillins

peripheral opioid receptor antagonists

peripheral vasodilators

peripherally acting antiobesity agents

phenothiazine antiemetics

phenothiazine antipsychotics

phenylpiperazine antidepressants

plasma expanders

platelet aggregation inhibitors

platelet-stimulating agents

polyenes

potassium-sparing diuretics

probiotics

progesterone receptor modulators

progestins

prolactin inhibitors

prostaglandin D2 antagonists

protease inhibitors

proton pump inhibitors

psoralens

psychotherapeutic agents

psychotherapeutic combinations

purine nucleosides

pyrrolidine anticonvulsants

quinolones

radiocontrast agents

radiologic adjuncts

radiologic agents

radiologic conjugating agents

radiopharmaceuticals

RANK ligand inhibitors

recombinant human erythropoietins

renin inhibitors

respiratory agents

respiratory inhalant products

rifamycin derivatives

salicylates

sclerosing agents

second generation cephalosporins

selective estrogen receptor modulators

selective serotonin reuptake inhibitors

serotonin-norepinephrine reuptake inhibitors

serotoninergic neuroenteric modulators

sex hormone combinations

sex hormones

skeletal muscle relaxant combinations

skeletal muscle relaxants

smoking cessation agents

somatostatin and somatostatin analogs

spermicides

statins

sterile irrigating solutions

streptomyces derivatives

succinimide anticonvulsants

sulfonamides

sulfonylureas

synthetic ovulation stimulants

tetracyclic antidepressants

tetracyclines

therapeutic radiopharmaceuticals

thiazide diuretics

thiazolidinediones

thioxanthenes

third generation cephalosporins

thrombin inhibitors

thrombolytics

thyroid drugs

tocolytic agents

topical acne agents

topical agents

topical anesthetics

topical anti-infectives

topical antibiotics

topical antifungals

topical antihistamines

topical antipsoriatics

topical antivirals

topical astringents

topical debriding agents

topical depigmenting agents

topical emollients

topical keratolytics

topical steroids

topical steroids with anti-infectives

toxoids

triazine anticonvulsants

tricyclic antidepressants

trifunctional monoclonal antibodies

tumor necrosis factor (TNF) inhibitors

tyrosine kinase inhibitors

ultrasound contrast media

upper respiratory combinations

urea anticonvulsants

urinary anti-infectives

urinary antispasmodics

urinary pH modifiers

uterotonic agents

vaccine

vaccine combinations

vaginal anti-infectives

vaginal preparations

vasodilators

vasopressin antagonists

vasopressors

VEGFNEGFR inhibitors

viral vaccines

viscosupplementation agents

vitamin and mineral combinations

vitamins

Diagnostic Tests

17-Hydroxyprogesterone

ACE (Angiotensin I converting enzyme)

Acetaminophen

Acid phosphatase

ACTH

Activated clotting time

Activated protein C resistance

Adrenocorticotropic hormone (ACTH)

Alanine aminotransferase (ALT)

Albumin

Aldolase

Aldosterone

Alkaline phosphatase

Alkaline phosphatase (ALP)

Alpha1-antitrypsin

Alpha-fetoprotein

Alpha-fetoprotien

Ammonia levels

Amylase

ANA (antinuclear antbodies)

ANA (antinuclear antibodies)

Angiotensin-converting enzyme (ACE)

Anion gap

Anticardiolipin antibody

Anticardiolipin antivbodies (ACA)

Anti-centromere antibody

Antidiuretic hormone

Anti-DNA

Anti-Dnase-B

Anti-Gliadin antibody

Anti-glomerular basement membrane antibody

Anti-HBc (Hepatitis B core antibodies

Anti-HBs (Hepatitis B surface antibody

Antiphospholipid antibody

Anti-RNA polymerase

Anti-Smith (Sm) antibodies

Anti-Smooth Muscle antibody

Antistreptolysin O (ASO)

Antithrombin III

Anti-Xa activity

Anti-Xa assay

Apolipoproteins

Arsenic

Aspartate aminotransferase (AST)

B12

Basophil

Beta-2-Microglobulin Beta-hydroxybutyrate

B-HCG

Bilirubin

Bilirubin, direct

Bilirubin, indirect

Bilirubin, total

Bleeding time

Blood gases (arterial)

Blood urea nitrogen (BUN)

BUN

BUN (blood urea nitrogen)

CA 125

CA 15-3

CA 19-9

Calcitonin

Calcium

Calcium (ionized)

Carbon monoxide (CO)

Carcinoembryonic antigen (CEA)

CBC

CEA

CEA (carcinoembryonic antigen)

Ceruloplasmin

CHSOChloride

Cholesterol

Cholesterol, HDL

Clot lysis time

Clot retraction time

CMP

CO₂

Cold agglutinins

Complement C3

Copper

Corticotrophin releasing hormone (CRH) stimulation test

Cortisol

Cortrosyn stimulation test

C-peptide

CPK (Total)

CPK-MB

C-reactive protein

Creatinine

Creatinine kinase (CK)

Cryoglobulins

DAT (Direct antiglobulin test)

D-Dimer

Dexamethasone suppression test

DHEA-S

Dilute Russell viper venom

Elliptocytes.

Eosinophil

Erythrocyte sedimentation rate (ESR)

Estradiol

Estriol

Ethanol

Ethylene glycol

Euglobulin lysis

Factor V Leiden

Factor VIII inhibitor

Factor VIII level

Ferritin

Fibrin split products

Fibrinogen

Folate

Folate (serum

Fractional excretion of sodium (FENA)

FSH (follicle stimulating factor)

FTA-ABS

Gamma glutamyl transferase (GGT)

Gastrin

GGTP (Gamma glutamyl transferase)

Glucose

Growth hormone

Haptoglobin

HBeAg (Hepatitis Be antigen)

HBs-Ag (Hepatitis B surface antigen)